Wednesday, August 31, 2011

Penegra Tablets | Sildenafil Citrate | Dosage | Penegra Side effects

Penegra Tablets (Generic Viagra) - Active Ingredient And Chemical structure

Generic Viagra is an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). The active ingredient contained in Penegra tablets is Sildenafil citrate .Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water. The structure is shown below

Sildenafil Citrate structure


Generic Forms and Brand names of Viagra (Sildenafil citrate)

Penegra manufactured by Zydus Cadila, India is an effective treatment for erectile dysfunction, also known as male impotence .Viagra which has the active ingredient Sildenafil citrate is also sold as Kamagra, Caverta, Silagra, Revatio and under various other brand names.


Penegra Tablets (Sildenafil citrate) - Uses

Sildenafil citrate in the form of Penegra Tablets is used to treat erectile dysfunction, also known as male impotence. Penegra is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes of oral dosing in the fasted state. When Penegra is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in Time to reach maximum concentration of 60 minutes and a mean reduction in Concentration of 29%.


Penegra Tablets (Sildenafil citrate)- Preparations

Penegra is available as tablets of 25 mg, 50 mg and 100 mg . Each tablet of penegra (sildenafil citrate) is equivalent to 25 mg, 50 mg and 100 mg of sildenafil respectively for oral administration.


Penegra Tablets (Sildenafil citrate) - Storage Requirements

Penegra Tablets are to be stored at room temperature (25°C to 30°C). Store away from heat, moisture, and light.


Penegra Tablets - Dosage

For most patients, the recommended dose of Penegra is 50 mg taken, as needed, approximately 1 hour before sexual activity. Penegra may however be taken anywhere from 4 hours to half an hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once a day.


Penegra Tablets (Sildenafil citrate) - Contraindications

Penegra is contraindicated in patients with a known hypersensitivity to Sildenafil citrate or to any inactive component of the tablet. Penegra (Sildenafil citrate) was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using organic nitrates, either regularly and/or intermittently, in any form is therefore contraindicated. There is a potential for cardiac risk of sexual activity in patients with preexisting cardiovascular disease. Therefore, treatments for erectile dysfunction, including Sildenafil citrate, should not be generally used in men for whom sexual activity is inadvisable because of their underlying cardiovascular status.


Side Effects Of Penegra Tablets (Sildenafil citrate)

The most common side effects of Penegra are Headache, Flushing,Dyspepsia, Nasal Congestion, Urinary Tract Infection, Abnormal Vision (Mild and transient, predominantly color tinge to vision, but also increased sensitivity to light or blurred vision), Diarrhea, Dizziness and Rash.


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Tuesday, August 30, 2011

Lanzol Capsules | Generic Prevacid | Lansoprazole | Dosage | Uses | Side effects

Lanzol Capsules (Generic Prevacid) - Active Ingredient And Chemical structure

The active ingredient contained in Lanzol Capsules is Lansoprazole. Lansoprazole is a white to brownish white odorless crystalline powder which melts with decomposition at approximately 166°C. Lansoprazole is freely soluble in dimethylformamide; soluble in methanol; sparingly soluble in ethanol; slightly soluble in ethyl acetate, dichloromethane and acetonitrile; very slightly soluble in ether; and practically insoluble in hexane and water. The structure is shown below

Structure Of Lansoprazole


Generic Forms and Brand names of Generic Prevacid (Generic Prevacid)

Lanzol Capsule manufactured by Cipla Ltd., India is an effective treatment for used to treat and prevent Duodenal Ulcer and gastric ulcers, Gastroesophageal Reflux Disease (GERD),erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Prevacid which has the active ingredient Lansoprazole is also sold as and under various other brand names.


Lanzol Capsules (Lansoprazole) - Uses

Lansoprazole in the form of Generic Prevacid Capsules (Lanzol Capsules) is used in the treatment of the below listed indications:
Short-Term Treatment of Active Duodenal Ulcer
Lanzol is indicated for short-term treatment (up to 4 weeks) for healing and symptom relief of active duodenal ulcer.
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Lanzol in combination with amoxicillin plus clarithromycin as triple therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.
Lanzol in combination with amoxicillin as dual therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected.
Maintenance of Healed Duodenal Ulcers
Lanzol is indicated to maintain healing of duodenal ulcers. Controlled studies do not extend beyond 12 months.
Short-Term Treatment of Active Benign Gastric Ulcer
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of active benign gastric ulcer.
Healing of NSAID-Associated Gastric Ulcer
Lanzol is indicated for the treatment of NSAID-associated gastric ulcer in patients who continue NSAID use. Controlled studies did not extend beyond 8 weeks.
Risk Reduction of NSAID-Associated Gastric Ulcer
Lanzol is indicated for reducing the risk of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID. Controlled studies did not extend beyond 12 weeks.
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD
Lanzol is indicated for the treatment of heartburn and other symptoms associated with GERD.
Short-Term Treatment of Erosive Esophagitis
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of all grades of erosive esophagitis. For patients who do not heal with Lanzol for 8 weeks (5-10%), it may be helpful to give an additional 8 weeks of treatment. If there is a recurrence of erosive esophagitis an additional 8-week course of Lanzol may be considered.
Maintenance of Healing of Erosive Esophagitis
Lanzol is indicated to maintain healing of erosive esophagitis. Controlled studies did not extend beyond 12 months.
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome
Lanzol is indicated for the long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome.


Lanzol Capsules (Generic Prevacid) - Preparations

Lanzol Capsules(Lansoprazole) is available as tablets of 15 mg and 30 mg .


Lanzol Capsules (Generic Prevacid) - Storage Requirements

Lanzol Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Lanzol Capsules - Dosage

The recommended dosage of Lanzol Capsules (Generic Prevacid) for variuous indications is given below:

IndicationRecommended Adult Dose Frequency
Duodenal Ulcers
Short-Term Treatment15 mg Once daily for 4 weeks
Maintenance of Healed 15 mg Once daily
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Triple Therapy
Lanzol30 mgTwice daily (q12h) for 10 or 14 days
Amoxicillin 1 gram Twice daily (q12h) for 10 or 14 days
Clarithromycin500 mgTwice daily (q12h) for 10 or 14 days
Dual Therapy:
Lanzol 30 mgThree times daily (q8h) for 14 days
Amoxicillin1 gramThree times daily (q8h) for 14 days
Benign Gastric Ulcer
Short-Term Treatment30 mgOnce daily for up to 8 weeks
NSAID-associated Gastric Ulcer
Healing30 mgOnce daily for 8 weeks
Risk Reduction15 mgOnce daily for up to 12 weeks
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD 15 mgOnce daily for up to 8 weeks
Short -Term Treatment of Erosive Esophagitis 30 mgOnce daily for up to 8 weeks

Side Effects Of Lanzol

The most common side effects of are Abdominal Pain, Constipation, Diarrhea, Nausea. There are also some rarely occuring side effects that may occur in less than 1% of the patients undergoing Lanzol therapy.


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Friday, August 26, 2011

Zinetac Tablets | Generic Zantac | Dosage | Uses | Side effects

Zinetac Tablets (Generic Zantac) - Active Ingredient And Chemical structure

The active ingredient contained in Zinetac Tablets is Ranitidine Hydrochloride. Ranitidine HCl is a white to pale yellow, granular substance that is soluble in water. It has a slightly bitter taste and sulfur like odour.The structure is shown below

Structure Of Ranitidine


Generic Zantac (Ranitidine HCl) - Uses

Generic Zantac in the form of Zinetac Tablets is used for the:
1.Short term treatment of active duodenal ulcer. Most patients undergoing treatment heal within 4 weeks of Zinetac therapy.
2.Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.
3.The treatment of pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome and systemic mastocytosis).
4.Short term treatment of active, benign gastric ulcer. Most patients undergoing treatment heal within 6 weeks.
5. Maintenance therapy for gastric ulcer patients at reduced dosage after healing of acute ulcers.
6. Treatment of GERD. Symptomatic relief commonly occurs within 24 hours after starting therapy with Zinetac 150 mg twice a day.
7. Treatment of endoscopically diagnosed erosive esophagitis. Symptomatic relief of heartburn commonly occurs within 24 hours of therapy initiation with Zinetac 150 mg four times a day.
8. Maintenance of healing of erosive esophagitis.
Concomitant antacids should be given as needed for pain relief to patients with active duodenal ulcer; active, benign gastric ulcer; hypersecretory states; GERD; and erosive esophagitis.


Generic Forms and Brand names of Zantac (Ranitidine HCl)

Zinetac Tablets manufactured by GlaxoSmithKline, India is an effective treatment for the conditions that cause your body to make too much stomach acid. Zantac which has the active ingredient Ranitidine Hydrochloride is also sold under various other brand names.


Zinetac Tablets (Generic Zantac) - Preparations

Zinetac Tablets is available as tablets of 150 mg and 300 mg . Each Zinetac 150 mg Tablet for oral administration contains 168 mg of ranitidine HCl equivalent to 150 mg of ranitidine.


Zinetac Tablets (Generic Zantac) - Storage Requirements

Zinetac Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.


Zinetac Tablets (Generic Zantac) - Dosage

The recommended dosage for the various conditions being treated is given below. Please consult your doctor for exact dosing instructions.
Active Duodenal Ulcer: The recommended adult oral dosage of Zinetac Tablets for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The recommended adult oral dosage is 150 mg twice a day.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice a day.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice a day.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg 4 times a day.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice a day.

Zinetac Tablets (Generic Zantac) - Contraindications

Zinetac Tablets is contraindicated for patients known to have hypersensitivity to Ranitidine Hydrochloride or any inactive ingredient present in the medication.


Side Effects Of Zinetac Tablets (Generic Zantac)

The most common side effects of Zinetac Tablets (Ranitidine HCl) are
Central Nervous System: Rarely, malaise, dizziness, somnolence, insomnia, and vertigo. Rare cases of reversible mental confusion, agitation, depression, and hallucinations have been reported, predominantly in severely ill elderly patients. Rare cases of reversible blurred vision as well as of reversible involuntary motor disturbances have also been received.
Cardiovascular: As with other H2-blockers, rare reports of arrhythmias such as tachycardia, bradycardia, atrioventricular block, and premature ventricular beats.
Gastrointestinal: Constipation, diarrhea, nausea/vomiting, abdominal discomfort/pain, and rare reports of pancreatitis.
Hepatic: There have been occasional reports of hepatocellular, cholestatic, or mixed hepatitis, with or without jaundice. In such circumstances, ranitidine should be immediately discontinued. These events are usually reversible, but in rare circumstances death has occurred. Rare cases of hepatic failure have also been reported.
Musculoskeletal: Rare reports of arthralgias and myalgias.
Hematologic: Blood count changes (leukopenia, granulocytopenia, and thrombocytopenia) that were usually reversible have occurred in a few patients. There were rare cases of agranulocytosis, pancytopenia, sometimes with marrow hypoplasia, and aplastic anemia and exceedingly rare cases of acquired immune hemolytic anemia that have been reported.
Endocrine: Controlled studies in animals and man have shown no stimulation of any pituitary hormone by Ranitidine HCl and no antiandrogenic activity, and cimetidine-induced gynecomastia and impotence in hypersecretory patients have resolved when Zinetac has been substituted. However, occasional cases of gynecomastia, impotence, and loss of libido have been reported in male patients receiving Zinetac , but the incidence did not differ from that in the general population.
Integumentary: Rash, including rare cases of erythema multiforme. Rare cases of alopecia and vasculitis.
Other Side Effects: The other side effects reported with Zinetac (Ranitidine HCl) use are Rare cases of hypersensitivity reactions (e.g., bronchospasm, fever, rash, eosinophilia), anaphylaxis, angioneurotic edema, and small increases in serum creatinine.


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Evalon Tablets | Estriol | Ovestin | Dosage | Uses | Side effects

Evalon Tablets (Estriol) - Active Ingredient And Chemical structure

The active ingredient contained in Evalon Tablets is Estriol. Estriol is a white odorless crystalline powder with a melting point of 282&ndeg;C . It is insoluble in water, sparingly soluble in ethanol and completely soluble in acetone, dioxane, diethyl ether, and vegetable oils. The structure is shown below

Structure Of Estriol


Generic Forms and Brand names of Estriol (Ovestin)

Evalon Tablets manufactured by Organon, India (a subsidiary of Schering-Plough Corporation, Part of Merck & Co. Inc.) is an effective treatment for distressing symptoms during menopause. Ovestin which has the active ingredient Estriol is also sold as Lynoral and under various other brand names.


Evalon Tablets (Estriol) - Uses

Evalon Tablets are prescribed as Hormone replacement therapy (HRT) for menopausal symptoms due to the loss of oestrogen production in postmenopausal women . Estriol is also used for treating Infertility due to cervical hostility.


Evalon Tablets (Estriol) - Preparations

Evalon Tablets is available as tablets of 1 mg and 2 mg.


Evalon Tablets (Estriol) - Storage Requirements

Evalon Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Evalon Tablets (Estriol) - Dosage

Treatment of estrogen deficiency symptoms:
The recommended dosage is 4-8 mg per day during the first weeks, followed by a gradual reduction. The lowest effective dosage of Estriol should be used. In case of long term Evalon therapy in women with an intact uterus, monitoring of the endometrium or, alternatively, concomitant use of a progestagen is recommended.
Infertility due to cervical hostility:
The recommended dosage in general is 1-2 mg per day on days 6-15 of the menstrual cycle. However, for some patients dosages as low as 1 mg per day are sufficient, whereas others may need up to 8 mg per day. Therefore, the dosage should be increased each month until an optimal effect on the cervical mucus is obtained.
Please consult your doctor for your exact dosing schedule.


Evalon Tablets (Estriol) - Contraindications

Hypersensitivity to the active ingredient Estriol or any other inactive ingredient present in Evalon Tablets
Known, past or suspected breast cancer
Known or suspected estrogen-dependent malignant tumors (e.g. endometrial cancer)
Undiagnosed genital bleeding
Untreated endometrial hyperplasia
Previous idiopathic or current venous thromboembolism (deep venous thrombosis, pulmonary embolism)
Active or recent arterial thromboembolic disease (e.g. angina, myocardial infarction)
Acute liver disease, or a history of liver disease as long as liver function tests failed to return to normal
Porphyria (Rare inherited disorders in which an important part of hemoglobin, called heme, is not made properly)
Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption


Side Effects Of Evalon Tablets (Estriol)

The most common side effects of Estriol are Breast discomfort and pain,Postmenopausal spotting,Cervical discharge,Nausea and Fluid retention. Estriol Therapy should be discontinued if any of the following situations arise: Jaundice or deterioration in liver function, Significant increase in blood pressure, New onset of migraine-type headache, Pregnancy or Endometrial hyperplasia.

Thursday, August 25, 2011

Eltroxin Tablets | Generic Synthroid | Dosage | Uses | Side effects

Eltroxin Tablets (Generic Synthroid) - Active Ingredient And Chemical structure

The active ingredient contained in Eltroxin Tablets is Levothyroxine Sodium . The structure is shown below

Structure Of  Levothyroxine Sodium


Eltroxin (Generic Synthroid) - Uses

Generic Synthroid in the form of Eltroxin Tablets is used as replacement or supplemental therapy in congenital or acquired hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis.
Eltroxin is also used in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules.


Generic Forms and Brand names of Synthroid

Eltroxin Tablets manufactured by GlaxoSmithKline, India is a hormone replacement medication usually given to patients with hypothyroidism and is also used to treat goiter. Synthroid which has the active ingredient Levothyroxine Sodium is also sold as Thyrax, Euthyrox, Levaxin, L-thyroxine, Eltroxin, Thyrax, Duotab, Thyrox, Eutirox, Tirosint, Levoxyl, Levothroid, Unithroid and under various other brand names.


Eltroxin (Generic Synthroid) - Preparations

Eltroxin (Generic Synthroid) is available as tablets of 50 mcg and 100 mcg. Eltroxin (levothyroxine sodium tablets) contains synthetic crystalline levothyroxine (T4) sodium. Synthetic T4 is identical to that produced in the human thyroid gland.


Eltroxin (Generic Synthroid) - Storage Requirements

Eltroxin Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Eltroxin Tablets - Dosage

Eltroxin is administered as a single daily dose, preferably one-half to one hour before breakfast. Eltroxin tablets should be swallowed whole, and taken with a full glass of water. Eltroxin tablets should not be split.
Eltroxin tablets should preferably be taken on an empty stomach. Eltroxin should be taken at least 4 hours apart from drugs that are known to interfere with its absorption. The average full replacement dose of levothyroxine sodium is approximately 1.7 mcg/kg/day (e.g., 100-125 mcg/day for a 70 kg adult). Older patients may require less than 1 mcg/kg/day. Please consult your doctor for exact dosing instructions. Dosage are individualized as per requirement of each patient.


Side Effects Of Eltroxin (Generic Synthroid)

The adverse effects of levothyroxine therapy are primarily those of hyperthyroidism due to therapeutic overdosage. The most common side effects are listed below:
General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating;
Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia;
Musculoskeletal: tremors, muscle weakness;
Cardiovascular: palpitations, tachycardia, arrythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest;
Respiratory: dyspnea;
Gastrointestinal: diarrhea, vomiting, abdominal cramps and elevations in liver function tests;
Dermatologic: hair loss, flushing;
Endocrine: decreased bone mineral density;
Reproductive: menstrual irregularities, impaired fertility.
Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.
Seizures have been reported rarely with the institution of levothyroxine therapy.
Inadequate levothyroxine dosage will produce or fail to ameliorate the signs and symptoms of hypothyroidism.
Hypersensitivity Reactions:Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various GI symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.


Eltroxin Tablets - Contraidications

Eltroxin (Levothyroxine Sodium) is contraindicated in patients with untreated subclinical (suppressed serum TSH level with normal T3 and T4 levels) or overt thyrotoxicosis of any etiology and in patients with acute myocardial infarction. Eltroxin (Levothyroxine Sodium) is contraindicated in patients with uncorrected adrenal insufficiency since thyroid hormones may precipitate an acute adrenal crisis by increasing the metabolic clearance of glucocorticoids. Eltroxin is contraindicated in patients with hypersensitivity to Levothyroxine Sodium or any of the inactive ingredients in Eltroxin tablets.


Eltroxin Tablets - Overdosage And Overdose Symptoms

The signs and symptoms of overdosage Eltroxin Tablets of are those of hyperthyroidism . In addition, confusion and disorientation may occur. Cerebral embolism, shock, coma, and death have been reported. Seizures have occurred in a child ingesting approximately 18 mg of levothyroxine. Symptoms may not necessarily be evident or may not appear until several days after ingestion of levothyroxine sodium.


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Friday, August 19, 2011

Cipla Clopivas Tablets | Clopidogrel | Uses | Clopivas Side effects

Clopivas Tablets (Generic Plavix) - Active Ingredient And Chemical structure

The active ingredient contained in Clopivas Tablets is Clopidogrel Bisulfate. Clopidogrel bisulfate is a white to off-white powder which is practically insoluble in water. The structure is shown below
Structure of Clopidogrel Bisulfate


Clopivas Tablets (Clopidogrel) - Preparations

Clopivas Tablets are available as oral tablets of 75 mg . Each film coated tablet contains 75 mg of Clopidogrel Bisulfate


Generic Forms and Brand names of Plavix (Clopidogrel Bisulfate)

Clopivas manufactured by Cipla Ltd., India is an effective treatment for Acute Coronary Syndrome, Myocardial Infarction, Recent Stroke or Established Peripheral Arterial Disease. Generic Plavix which has the active ingredient Clopidogrel Bisulfate is also sold as Plagril tablets and under various other brand names.


Clopivas Tablets - Storage Requirements

Clopivas Tablets are to be stored at room temperature (15°C to 30°C) in a cool and dry place. Store away from heat, moisture, and light. Keep out of reach of children and pets.


Clopivas Tablets - Uses

Clopivas (Clopidogrel) is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of adenosine diphosphate (ADP) receptors on platelets. Clopivas used to treat:
Acute coronary syndrome
Patients with non-ST-segment elevation ACS
Patients with ST-elevation myocardial infarction (STEMI)
Recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease.


Clopivas Tablets (Clopidogrel Bisulfate) - Dosage

Clopivas Tablets can be administered with or without food. The dosing for Clopivas Tablets is as follows:
Acute coronary syndrome
-For patients with Non-ST-segment elevation ACS (UA/NSTEMI): Initiate Clopivas (clopidogrel) with a single 300 mg oral loading dose followed by 75 mg once daily, in combination with aspirin (75-325 mg once daily)
-For patients with STEMI: The recommended dose of Clopivas (clopidogrel) is 75 mg once daily, in combination with aspirin (75-325 mg once daily), with or without a loading dose and with or without thrombolytics
Recent MI, recent stroke, or established peripheral arterial disease (PAD):The recommended dose of Clopivas is 75 mg once daily orally, with or without food.


Clopivas Tablets (Clopidogrel Bisulfate) - Contraindications

Clopivas Tablets is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage. Clopivas Tablets are also contraindicated in patients with hypersensitivity to Clopidogrel Bisulfate or any any inactive ingredient of the product.


Side Effects Of Clopivas Tablets (Clopidogrel Bisulfate)

Clopivas is generally well tolerated. Side effects of Clopivas Tablets (Clopidogrel) that have been reported include bleeding, including life-threatening and fatal bleeding, thrombotic thrombocytopenic purpura (TTP), gastrointestinal hemorrhage, pruritus, chest pain, headache, upper respiratory tract infection, rash, edema and influenza like symptoms.


Further Information About Cipla Clopivas Tablets

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Wednesday, August 17, 2011

Losacar Tablets | Generic Losartan | Dosage | Uses | Side effects

Losacar Tablets (Generic Losartan) - Active Ingredient And Chemical structure

Losacar (Losartan Potassium) is an angiotensin II receptor (type AT1) antagonist. Losartan Potassium is a white to off-white free-flowing crystalline powder which is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents. The structure is shown below
Structure Of Losartan


Generic Losartan (Losartan Potassium)- Uses

Generic Losartan in the form of Losacar Tablets is used for the treatment of hypertension. It is also used for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio =300 mg/g) in patients with type 2 diabetes and a history of hypertension.


Generic Forms and Brand names of Losartan (Losartan Potassium)

Losacar manufactured by Zydus Cadila, India is an effective treatment for hypertension. Losartan which has the active ingredient Losartan Potassium is also sold as Losacar-A, Hyzaar, Cozaar, Cosart and under various other brand names.


Losacar Tablets (Generic Losartan) - Preparations

The active ingredient contained in Losacar Tablets is losartan potassium. Losacar is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of Losartan Potassium


Losacar Tablets (Generic Losartan) - Storage Requirements

Losacar Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Losacar Tablets (Generic Losartan) - Dosage

For Adult Hypertensive Patients, the recommended starting dose of Losacar Tablets is 50 mg once daily, with 25 mg used in patients with possible depletion of intravascular volume (e.g., patients treated with diuretics) Dosing has to be individualized. Please consult your doctor for exact dosing instructions. Losacar Tablets may be administered with other antihypertensive agents, and with or without food.


Losacar Tablets (Generic Losartan) - Contraindications

Losacar is contraindicated in patients who are hypersensitive to any component of this product.


Side Effects Of Losacar Tablets (Losartan Potassium)

The most common side effects of Losacar Tablets (Losartan Potassium) are Cramps in muscle, Back Pain, LegPain, Dizziness, Nasal Congestion, Infection in upper respiratory tract, Sinusitis. Less common side effects that may occur are asthenia/fatigue, edema/swelling, abdominal pain, chest pain, nausea, headache, pharyngitis, diarrhea, dyspepsia, myalgia, insomnia, cough, sinus disorder.


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Friday, August 12, 2011

Fluvoxin Tablets | Generic Luvox | Dosage | Uses | Side effects

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Fluvoxin Tablets (Generic Luvox) - Active Ingredient And Chemical structure

The active ingredient contained in is Fluvoxamine maleate. Fluvoxamine maleate is a white to off white, odorless, crystalline powder which is sparingly soluble in water, freely soluble in ethanol and chloroform. The structure is shown below

Structure Of Fluvoxamine


Generic Forms and Brand names of Luvox (Fluvoxamine Maleate)

Fluvoxin Tablets manufactured by SUN Pharmaceuticals, India is an effective treatment for obsessions and compulsions in patients with obsessive compulsive disorder (OCD). Luvox which has the active ingredient Fluvoxamine maleate is also sold under various other brand names.


Fluvoxin Tablets (Generic Luvox) Preparations

Fluvoxin Tablets (Fluvoxamine Maleate) Tablets are available in 25 mg, 50 mg and 100 mg tablets for oral administration.


Fluvoxin Tablets - Contraindications

The contraindications of Fluvoxin Tablets (Generic Luvox) are as follows:
Coadministration of tizanidine, thioridazine, alosetron, or pimozide with LUVOX Tablets is contraindicated.The use of MAOI's concomitantly with or within 14 days of treatment with LUVOX Tablets is contraindicated.


Fluvoxin Tablets - Storage Requirements

Fluvoxin Tablets (Generic Luvox) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.



Fluvoxin Tablets (Generic Luvox) - Uses

Generic Luvox in the form of Fluvoxin Tablets is used to treat obsessions and compulsions in patients with obsessive compulsive disorder (OCD). Fluvoxin Tablets (Fluvoxamine Maleate) is also prescribed to treat major depressive disorder (MDD) and anxiety disorders, such as generalized anxiety disorder (GAD), panic disorder, and post-traumatic stress disorder (PTSD).



Fluvoxin Tablets - Dosage

The recommended starting dose of Fluvoxin Tablets for Adults is 50 mg at bedtime, with increases of 50 mg every 4 to 7 days as tolerated until maximum therapeutic effect is obtained. Dosage is not to exceed 300 mg/day. The Daily doses over 100mg should be divided. When discontinuing Generic Luvox Gradual dose reduction is recommended. Please consult your doctor for exact dosing instructions.



Side Effects Of Fluvoxin Tablets (Generic Luvox)

The most common side effects of are nausea, somnolence, insomnia, asthenia, nervousness, dyspepsia, abnormal ejaculation, sweating ,anorexia, tremor, and vomiting. Other side effects that may occur are anorgasmia, decreased libido, dry mouth, rhinitis, taste perversion, and urinary frequency in patients with OCD; and agitation, depression, dysmenorrhea, flatulence, hyperkinesia, and rash in pediatric patients with OCD.


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Thursday, August 11, 2011

Pramipex Tablets | Generic Mirapex | Dosage | Uses | Side effects

Pramipex Tablets (Generic Mirapex) - Active Ingredient And Chemical structure

The active ingredient contained in Pramipex Tablets is Pramipexole Dihydrochloride. Pramipexole dihydrochloride is a white to off-white powder that is more than 20% soluble in water. The structure is shown below
Structure Of Pramipexole


Generic Forms and Brand names of Mirapex (Pramipexole Dihydrochloride)

Pramipex Tablets manufactured by SUN Pharmaceuticals, India is an effective treatment for idiopathic Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome (RLS). Mirapex which has the active ingredient Pramipexole Dihydrochloride is also sold as Pramipexin, Sifrol and under various other brand names.


Pramipex Tablets (Generic Mirapex) - Preparations

Pramipex Tablets is available as tablets of 0.125 mg, 0.25 mg, 0.5 mg, 1 mg and 1.5 mg. Pramipex Tablets for oral administration, contain 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, or 1.5 mg of pramipexole dihydrochloride monohydrate.


Pramipex Tablets (Generic Mirapex) - Storage Requirements

Pramipex Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Mirapex (Pramipexole Dihydrochloride) - Uses

Generic Mirapex (Pramipexole Dihydrochloride) in the form of Pramipex Tablets is used to treat the signs and symptoms of idiopathic Parkinson's disease and for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).


Pramipex Tablets (Generic Mirapex) - Contraindications

Pramipex Tablets are contraindicated in patients who have demonstrated hypersensitivity to Pramipexole Dihydrochloride or any of the inactive ingredients.


Pramipex Tablets (Generic Mirapex) - Dosage

For the treatment of Parkinson's disease the recommended starting dose is 0.375 mg/day given in three divided doses and should not be increased more frequently than every 5 to 7 days. For maintenance treatment Pramipex Tablets (pramipexole dihydrochloride) were effective and well tolerated over a dosage range of 1.5 to 4.5 mg/day administered in equally divided doses three times per day. In the case of Restless Legs Syndrome the recommended starting dose of Pramipex Tablets is 0.125 mg taken once daily 2 to 3 hours before bedtime.


Side Effects Of Pramipex Tablets (Generic Mirapex)

The most common side effects of are Pramipex Tablets nausea, dizziness, somnolence, insomnia, constipation, asthenia, and hallucinations.


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Tuesday, August 9, 2011

Attentrol Capsules | Generic Strattera | Dosage | Uses | Side effects

Attentrol Capsules (Generic Strattera) - Active Ingredient And Chemical structure

The active ingredient contained in Attentrol Capsules is Atomoxetine Hydrochloride . Atomoxetine HCl is a white to practically white solid, which has a solubility of 27.8 mg/mL in water. The structure is shown below

Structure Of Atomoxetine Hydrochloride


Attentrol Capsules (Generic Strattera)- Uses

Atomoxetine Hydrochloride in the form of Generic Strattera Capsules (Attentrol Capsules) is a selective norepinephrine reuptake inhibitor used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).


Generic Forms and Brand names of Strattera (Atomoxetine Hydrochloride)

Attentrol manufactured by Sun Pharmaceutical Industries Ltd., India is an effective treatment for treatment of Attention Deficit Hyperactivity Disorder (ADHD). Strattera which has the active ingredient Atomoxetine Hydrochloride is also sold as Attentin, Tomoxetin and under various other brand names. Strattera (Atomoxetine HCl) is a selective norepinephrine reuptake inhibitor.


Attentrol Capsules (Generic Strattera) - Preparations

Attentrol is available as Capsules of 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg and 100 mg. Each capsule contains atomoxetine HCl equivalent to 10, 18, 25, 40, 60, 80, or 100 mg of atomoxetine.


Attentrol Capsules (Generic Strattera) - Storage Requirements

Attentrol Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Attentrol Capsules (Generic Strattera) - Contraindications

Attentrol Capsules are contraindicated in the following cases:
Hypersensitivity to Atomoxetine HCl or other constituents of product. Use of Attentrol Capsules within 2 weeks after discontinuing MAOI or other drugs that affect brain monoamine concentrations. In patients with Narrow Angle Glaucoma.


Attentrol Capsules (Generic Strattera) - Dosage

The recommended starting dose of Attentrol Capsules for adults as well as Children and adolescents over 70 kg is 40 mg once a day.


Warnings And Precautions When Using Attentrol Capsules (Generic Strattera)


Suicidal Ideation - Monitor for suicidality, clinical worsening, and unusual changes in behavior.
Severe Liver Injury - Attentrol Capsules should be discontinued and not restarted in patients with jaundice or laboratory evidence of liver injury.
Serious Cardiovascular Events - Sudden death, stroke and myocardial infarction have been reported in association with atomoxetine treatment. Generic Strattera generally should not be used in children or adolescents with known serious structural cardiac abnormalities, cardiomyopathy, serious heart rhythm bnormalities, or other serious cardiac problems. Consideration has be given to not using Generic Strattera in adults with clinically significant cardiac abnormalities.
Emergent Cardiovascular Symptoms - Patients should undergo prompt cardiac evaluation.
Effects on Blood Pressure and Heart Rate - Can increase blood pressure and heart rate; orthostasis, syncope and Raynaud's phenomenon may occur. Use with caution in patients with hypertension, tachycardia, or cardiovascular or cerebrovascular disease.
Emergent Psychotic or Manic Symptoms - Discontinuing treatment with Attentrol Capsules should be considered if such new Psychotic or Manic Symptoms symptoms occur.
Bipolar Disorder - Patients should be screened to avoid possible induction of a mixed/manic episode.
Aggressive behavior - Aggressive behavior or hostility in patients undergoing treatment should be monitored.
Possible allergic reactions - Possible allergic reactions including anaphylactic reactions, angioneurotic edema, urticaria, and rash can occur in patients undergoing Attentrol therapy.
Effects on Urine Outflow - Urinary hesitancy and retention may occur.
Priapism - Prompt medical attention is required in the event of suspected priapism.
Growth - Height and weight should be monitored in pediatric patients. Concomitant Use of Potent CYP2D6 Inhibitors or Use in patients known to be CYP2D6 PMs may require dose adjustment of Attentrol.


Side Effects Of Attentrol Capsules (Generic Strattera)

The most common side effects of Attentrol Capsules are:
Child and Adolescent Clinical Trials - Nausea, vomiting, fatigue, decreased appetite, abdominal pain, and somnolence.
Adult Clinical Trials - Constipation, dry mouth, nausea, fatigue, decreased appetite, insomnia, erectile dysfunction, urinary hesitation and/or urinary retention and/or dysuria, dysmenorrhea, and hot flush.
There have been rare cases of clinically significant liver injury that were considered probably or possibly related to Strattera use in postmarketing experience. Generic Strattera (Attentrol Capsules) should be discontinued in patients with jaundice or laboratory evidence of liver injury, and should not be restarted.


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Sirdalud Tablets | Generic Zanaflex | Dosage | Uses | Side effects

Sirdalud Tablets (Generic Zanaflex) - Active Ingredient And Chemical structure

The active ingredient contained in Sirdalud Tablets (Generic Zanaflex) is Tizanidine Hydrochloride. Tizanidine HCl (tizanidine) is a white to off-white, fine crystalline powder, which is 15 odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol. The structure is shown below

Structure Of Tizanidine HCl


Generic Forms and Brand names of Zanaflex (Tizanidine HCl)

Sirdalud Tablets manufactured by Novartis is used to help relax certain muscles in your body caused by medical problems. Zanaflex which has the active ingredient Tizanidine Hydrochloride is also sold under various other brand names.


Sirdalud Tablets - Preparations

Sirdalud tablets are available as 2 mg and 4 mg tablets for oral administration. Sirdalud tablets are composed of the active ingredient, tizanidine hydrochloride 29 (2.29 mg equivalent to 2 mg tizanidine base and 4.58 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, silicon dioxide colloidal, stearic acid microcrystalline cellulose and anhydrous lactose.


Sirdalud Tablets - Storage Requirements

Sirdalud Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Sirdalud Tablets - Uses

Tizanidine Hydrochloride in the form of Sirdalud Tablets is used to relax certain muscles in your body caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.


Sirdalud Tablets - Contraindications

Concomitant use of Sirdalud Tablets (tizanidine) with fluvoxamine or with ciprofloxacin, is contraindicated. This pharmacokinetic interaction can result in potentially serious adverse events. Sirdalud is also contraindicated in patients with known hypersensitivity to Tizanidine or other inactive ingredients.


Sirdalud Tablets - Dosage

The recommended starting dose of Sirdalud is a single oral dose of 4 mg due to dose related nature of tizanidine’s common adverse effects. The dose has to be gradually increased in 2 to 4 mg steps to optimum effect i.e. To obtain satisfactory reduction of muscle tone at a tolerated dose. Please consult your doctor for exact dosing instructions.


Side Effects Of Sirdalud Tablets

The most common side effects of Sirdalud Tablets are asthenia (weakness, fatigue and/or tiredness) , somnolence , dry mouth , increased spasm or tone , and dizziness . Less common side effects that may occur are were Infection Constipation Liver function tests abnormal, Vomiting, Speech disorder, Amblyopia (blurred vision), Urinary frequency, Flu symptom, SGPT/ALT increased, Dyskinesia ,Nervousness, Pharyngitis and Rhinitis


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Wednesday, August 3, 2011

Buspin Tablets | Generic Buspar | Dosage | Uses | Side effects

Buspin Tablets (Generic Buspar) - Active Ingredient And Chemical structure

The active ingredient contained in Buspin Tablets (Generic Buspar) is Buspirone HCl. Buspirone Hydrochloride is a white crystalline compound that is soluble in water. The structure is shown below
Structure Of Buspirone Hydrochloride


Generic Forms and Brand names of Buspar Tablets (Buspirone Hydrochloride)

Buspin Tablets manufactured by Intas Pharmaceuticals Ltd., India is an effective treatment for Generalized Anxiety Disorder (GAD) of very mild to moderate intensity, without any panic attacks. Buspar which has the active ingredient Buspirone Hydrochloride is also sold as Dividose and under various other brand names.


Buspin Tablets (Generic Buspar) - Uses

Generic Buspar Tablets in the form of Buspin Tablets is used for the management of anxiety disorders or for the short term relief of the symptoms of anxiety.


Buspin Tablets (Generic Buspar) - Preparations

Buspin is available as tablets of 5 mg, 10 mg, 15 mg, or 30 mg for oral administration. These tablets contains 5 mg, 10 mg, 15 mg or 30 mg of buspirone hydrochloride.


Buspin Tablets (Generic Buspar) - Storage Requirements

Buspin Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from Children and pets.


Buspin Tablets (Generic Buspar) - Dosage

The recommended initial dose is 15 mg daily (7.5 mg two times a day). Inorder to achieve an optimal therapeutic response, the dosage may be increased 5 mg per day, as needed at intervals of 2 to 3 days. The maximum daily dosage of Buspin should not exceed 60 mg per day.



Buspin Tablets (Generic Buspar) - Contraindications And Warnings


Buspin is contraindicated in patients hypersensitive to buspirone hydrochloride or to any inactive ingredient. Administration of Buspin tablets to a patient taking a monoamine oxidase inhibitor (MAOI) may pose a hazard. Occurrences of high blood pressure when Buspin (buspirone hydrochloride) has been added to a regimen including an MAOI have been reported.


Side Effects Of Buspin Tablets (Generic Buspar)

The most common side effects of Buspin Tablets include dizziness, nausea, headache, nervousness, lightheadedness, and excitement. Rarely occuring side effects that were reported post marketing include allergic reactions (including urticaria), angioedema, cogwheel rigidity, dizziness (rarely reported as vertigo), dystonic reactions (including dystonia), ataxias, extrapyramidal symptoms, dyskinesias (acute and tardive), ecchymosis, emotional lability, serotonin syndrome, transient difficulty with recall, urinary retention, visual changes (including tunnel vision), parkinsonism, akathisia, restless leg syndrome, and restlessness.


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Tuesday, August 2, 2011

Tryptomer Tablets | Generic Elavil | Dosage | Uses | Tryptomer Side effects

Tryptomer Tablets (Generic Elavil) - Active Ingredient And Chemical structure

The active ingredient contained in Tryptomer Tablets (Generic Elavil) is Amitriptyline Hydrochloride. Amitriptyline HCl is a white, odorless, crystalline compound that is freely soluble in water. The structure is shown below

Structure Of  Amitriptyline Hydrochloride


Generic Elavil (Amitriptyline Hydrochloride) - Uses

Amitriptyline Hydrochloride in the form of Generic Elavil Tablets (Tryptomer Tablets) is used to treat depresssion. Generic Elavil is also used aa a sedative, and is useful in depressed patients with insomnia, restlessness, and nervousness.


Generic Forms and Brand names of Elavil Tablets

Tryptomer manufactured by Wockhardt Ltd., India is an effective treatment for depression . It is also used to relive the symptoms of migraines, tension headaches, anxiety attacks and some schizophrenic symptoms. Elavil which has the active ingredient Amitriptyline Hydrochloride is also sold as Tryptizol, Laroxyl, Sarotex, Lentizol and under various other brand names.


Tryptomer Tablets Preparations

Tryptomer Tablets (Generic Elavil) are available as tablets of 10 mg, 25 mg and 75 mg.


Tryptomer Tablets - Storage Requirements

Tryptomer Tablets (Generic Elavil) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Tryptomer Tablets (Generic Elavil) - Dosage


The adult dosage for Tryptomer Tablets is 25 mg three times a day. The dosage may be increased if necessary to a total of 150 mg a day. In the case of adolescent and elderly Patients lower dosages are recommended. 10 mg three times a day or 10 mg twice with 20 mg at bedtime is recommended. Dosage should be started at a low level and increased gradually, after carefully observing the clinical response of the patient to Tryptomer and any evidence of intolerance.


Tryptomer Tablets (Generic Elavil) - Contraindications And Warnings

Tryptomer is contraindicated in patients who have shown prior hypersensitivity to the active ingredient Amitriptyline HCl or to any inactive ingredient.Tryptomer Tablets should not be given along with or within at least 14 days following the discontinuance of a monoamine oxidase inhibitor (MOI). Generic Elavil should not be used during the acute recovery phase following myocardial infarction, and in the presence of acute congestive heart failure.
Tryptomer may block the antihypertensive action of guanethidine or similarly acting compounds. Generic Elavil should be used with caution in patients with a history of seizures and, because of its atropine like action, in patients with a history of urinary retention, angle-closure glaucoma or increased intraocular pressure. In patients with angle-closure glaucoma, even average doses of Generic Elavil may precipitate an attack. Patients with cardiovascular disorders have to be observed closely.


Withdrawal Symptoms

Abrupt cessation of treatment after prolonged administration of Tryptomer Tablets may give rise to nausea, headache, and malaise. Gradual dosage reduction has been reported to produce, within two weeks, transient symptoms including irritability, restlessness, and dream and sleep disturbance.


Side Effects Of Tryptomer Tablets (Generic Elavil)

The most common side effects of Tryptomer Tablets are described below:
Cardiovascular:
Myocardial infarction; stroke; nonspecific EGG changes and changes in AV conduction; heart block; arrhythmias; hypotension, particularly orthostatic hypotension; syncope; hypertension; tachycardia; palpitation.
CNS and Neuromuscular:
Coma; seizures; hallucinations; delusions; confusional states;disorientation; incoordination; ataxia; tremors; peripheral neuropathy; numbness, tingling. and paresthesias of the extremities; extrapyramidal symptoms including abnormal involuntary movements and tardive dyskinesia; dysarthria; disturbed concentration; excitement; anxiety; insomnia; restlessness; nightmares; drowsiness; dizziness; weakness; fatigue; headache; syndrome of inappropriate ADH (antidiuretic hormone) secretion; tinnitus; alteration in EEG patterns.
Anticholinergic:
Paralytic ileus; hyperpyrexia; urinary retention; dilatation of the urinary tract; constipation; blurred vision, disturbance of accommodation, increased ocular pressure, mydriasis; dry mouth.
Allergic:
Skin rash; urticaria; photosensitization; edema of face and tongue.
Hematologic:
Bone marrow depression including agranulocytosis, leukopenia, thrombocytopenia; purpura; eosinophilia.
Gastrointestinal:
Rarely hepatitis (including altered liver function and jaundice); nausea; epigastric distress; vomiting; anorexia; stomatitis' peculiar taste; diarrhea; parotid swelling; black tongue
Endocrine:
Testicular swelling and gynecomastia in the male; breast enlargement and galactorrhea in the female; increased or decreased libido; impotence; elevation and lowering of blood sugar levels.
Other Adverse Reactions:
Alopecia; edema; weight gain or loss; urinary frequency; increased perspiration.