Wednesday, July 13, 2011

Asprito Tablets | Generic Abilify | Dosage | Uses | Side effects

Generic Abilify Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Generic Abilify Tablets is Aripiprazole. The structure is shown below

Structure Of Aripiprazole


Generic Forms and Brand names of Abilify (Aripiprazole)

Asprito manufactured by Intas Pharmaceuticals Ltd., India is an effective treatment for schizophrenia, certain symptoms of bipolar disorder and clinical depression. Generic Abilify which has the active ingredient Aripiprazole is also sold as Aripiprex and under various other brand names.


Generic Abilify (Asprito Tablets ) - Preparations

Asprito is available as tablets of 10 mg, 15 mg, 20 mg and 30 mg .


Generic Abilify (Asprito Tablets ) - Storage Requirements

Asprito Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture and light.


Generic Abilify (Asprito Tablets) - Uses


Generic Abilify Tablets in the form of Asprito tablets is used for:
Treatment of Schizophrenia in adults and adolescents aged 13 to 17 years
Treatment of manic or mixed episodes associated with Bipolar I Disorder as monotherapy or adjunctive to lithium or valproate in adults and pediatric patients aged 10 to 17 years

Adjunctive treatment of Major Depressive Disorder in adults as an injection for:Treatment of adults with agitation associated with Schizophrenia or Bipolar I Disorder, manic or mixed episodes


Generic Abilify (Asprito Tablets ) - Dosage


The recommended doses for various treatments are given below:
Schizophrenia - adults
Initial Dose: 10-15 mg /day
Recommended Dose: 10-15 mg /day
Maximum Dose: 30 mg /day
Schizophrenia - adolescents
Initial Dose: 2 mg /day
Recommended Dose: 10 mg /day
Maximum Dose: 30 mg /day
Bipolar Mania - adults monotherapy or as an adjunct to lithium or valproate
Initial Dose: 15 mg /day
Recommended Dose: 15 mg /day
Maximum Dose: 30 mg /day
Bipolar Mania - pediatric patients monotherapy or as an adjunct to lithium or valproate
Initial Dose: 2 mg /day
Recommended Dose: 10 mg /day
Maximum Dose: 30 mg /day
As an adjunct to antidepressants for the treatment of Major Depressive Disorder
Initial Dose: 2-5 mg /day
Recommended Dose: 5-10 mg /day
Maximum Dose: 15 mg /day


Generic Abilify (Asprito Tablets ) - Contraindications

Generic Abilify is contraindicated in all persons with a known hypersensitivity to Aripiprazole or any non active ingredient.


Side Effects Of Generic Abilify (Asprito Tablets )

The most common side effects of Asprito Tablets are akathisia, extrapyramidal disorder, somnolence, and tremor, sedation, restlessness, tremor, fatigue, nausea, blurred vision, salivary hypersecretion, constipation and dizziness.


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Generic Tamoxifen Tablets | Tamtero | Nolvadex Tablets | Dosage | Uses | Side effects

Generic Tamoxifen Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Generic Tamoxifen Tablets (also referred to as generic Nolvadex) is Tamoxifen Citrate. The structure is shown below

Structure  Of Tamoxifen Citrate


Generic Forms and Brand names of Nolvadex Tablets

Although Tamoxifen was discovered by ICI Pharmaceuticals (presently AstraZeneca) and is sold under the brand names Nolvadex, Istubal, and Valodex, the medication is still is widely referred to by its generic name "tamoxifen". Tamtero manufactured by Hetero Drugs Ltd, India is effective for treatment and prevention of breast cancer in men and women. Tamtero Tablets (tamoxifen citrate) Tablets, a nonsteroidal antiestrogen, are for oral administration. Generic Tamoxifen which has the active ingredient Tamoxifen Citrate is also sold as Istubal, Valodex, Tamoxifen Apo-Tamox; Gen-Tamoxifen, Novo-Tamoxifen, Tamofen, Tamone, Citofen, Crisafeno, Diemon, Istubol, Kessar, Noltam, Nourytam, Novo-Tamoxifen , Oncomox, PMS-Tamoxifen, Tamoxifene, Tamoxifen, Retaxim, Tamizam, Tamoxasta, Tamoxen, Valodex, Zemide, Tamoxifeno, Soltamox and under various other brand names.


Generic Tamoxifen Preparations

Generic Tamoxifen is available as Tamtero tablets of 10 mg. Each 10 mg tablet of Tamtero contains 15.2 mg of tamoxifen citrate which is equivalent to 10 mg of tamoxifen.


Generic Tamoxifen Tablets (Tamtero) - Storage Requirements

Tamtero Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Tamoxifen Tablets (Tamtero) - Uses


Generic Tamoxifen Tablets in the form of Tamtero Tablets is used to treat metastatic breast cancer adjuvant treatment of breast cancer, ductal carcinoma in situ as well as for reduction in breast cancer incidence in high risk women.
Metastatic Breast Cancer:
Generic Tamoxifen Tablets are effective in the treatment of metastatic breast cancer in women and men. In premenopausal women with metastatic breast cancer, Tamtero is an alternative to oophorectomy or ovarian irradiation.
Adjuvant Treatment of Breast Cancer:
Generic Tamoxifen Tablets are indicated for the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation.
Ductal Carcinoma in Situ (DCIS):
In women with DCIS, following breast surgery and radiation, Generic Tamoxifen Tablets are used to reduce the risk of invasive breast cancer
Reduction in Breast Cancer Incidence in High Risk Women:
Generic Tamoxifen Tablets are used to reduce the incidence of breast cancer in women at high risk for breast cancer.


Tamtero Tablets (Generic Tamoxifen) - Contraindications

Generic Tamoxifen is contraindicated in patients with known hypersensitivity to the drug or any of its ingredients.


Tamtero Tablets (Generic Tamoxifen) - Dosage


The recommended dosages of Tamtero Tablets (Generic Tamoxifen) are given below;
Breast Cancer:
For patients with breast cancer, the recommended daily dose is 20-40 mg. Dosages more than 20 mg per day should be given in divided doses (morning and evening).
Ductal Carcinoma in Situ (DCIS):
The recommended dose is Tamtero Tablets 20 mg daily for 5 years.
Reduction in Breast Cancer Incidence in High Risk Women:
The recommended dose is Tamtero Tablets 20 mg daily for 5 years.


Side Effects Of Generic Tamoxifen Tablets (Tamtero)

The most common side effects of Generic Tamoxifen Tablets are Hot Flashes, Vaginal Discharges, Vaginal Bleeding, Decreased Platelets count, Infection/Sepsis, Constipation, Alopecia, Allergy. Less frequently reported adverse reactions are vaginal bleeding, vaginal discharge, menstrual irregularities, skin rash and headaches. Most of the time these have not been of sufficient severity to require dosage reduction or discontinuation of treatment. Very rare reports of erythema multiforme, Stevens-Johnson syndrome, bullous pemphigoid, interstitial pneumonitis, hypersensitivity reactions including angioedema have been reported by patients undergoing treatment with Generic Tamoxifen.


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Monday, July 11, 2011

Plagril Tablets | Generic Plavix | Dosage | Uses | Side effects

Generic Plavix (Plagril Tablets) - Active Ingredient And Chemical structure

The active ingredient contained in Plagril Tablets is Clopidogrel Bisulfate. Clopidogrel bisulfate is a white to off-white powder. It is practically insoluble in water. The structure is shown below
Structure of Clopidogrel Bisulfate


Generic Forms and Brand names of Generic Plavix

Plagril manufactured by Dr. Reddy's Pharmaceuticals, India is an effective treatment to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Generic Plavix which has the active ingredient Clopidogrel Bisulfate is also sold under various other brand names.


Generic Plavix (Plagril Tablets) - Preparations

Plagril Tablets is available as oral tablets of 75 mg .


Plagril Tablets (Generic Plavix) - Storage Requirements

Plagril Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Plavix (Plagril Tablets) - Uses

Generic Plavix, a P2Y12 platelet inhibitor in the form of Plagril tablets is used to treat:
Acute coronary syndrome
Patients with non-ST-segment elevation ACS
Patients with ST-elevation myocardial infarction (STEMI)
Recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease.


Plagril Tablets (Generic Plavix) - Dosage

The dosing for Generic Plavix is as follows:
Acute coronary syndrome
- Non-ST-segment elevation ACS (UA/NSTEMI): 300 mg loading dose followed by 75 mg once daily, in combination with aspirin (75-325 mg once daily)
- STEMI: 75 mg once daily, in combination with aspirin (75-325 mg once daily), with or without a loading dose and with or without thrombolytics
Recent MI, recent stroke, or established peripheral arterial disease: 75 mg once daily


Plagril Tablets (Generic Plavix) - Contraindications

Generic Plavix is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage. Plagril Tablets are also contraindicated in patients with hypersensitivity to Clopidogrel Bisulfate or any any inactive ingredient of the product.


Side Effects Of Plagril Tablets (Generic Plavix)

The most commonly reported side effects of Plagril Tablets are Bleeding, including life-threatening and fatal bleeding. Less common side effects that may occur are Severe neutropenia (low white blood cells), Thrombotic thrombocytopenic purpura (TTP), skin irritations, respiratory difficulties, bloody stools and vomit, bloating of facial features, limbs and joints, exhaustion.


Further Information

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