Friday, August 12, 2011

Fluvoxin Tablets | Generic Luvox | Dosage | Uses | Side effects

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Fluvoxin Tablets (Generic Luvox) - Active Ingredient And Chemical structure

The active ingredient contained in is Fluvoxamine maleate. Fluvoxamine maleate is a white to off white, odorless, crystalline powder which is sparingly soluble in water, freely soluble in ethanol and chloroform. The structure is shown below

Structure Of Fluvoxamine


Generic Forms and Brand names of Luvox (Fluvoxamine Maleate)

Fluvoxin Tablets manufactured by SUN Pharmaceuticals, India is an effective treatment for obsessions and compulsions in patients with obsessive compulsive disorder (OCD). Luvox which has the active ingredient Fluvoxamine maleate is also sold under various other brand names.


Fluvoxin Tablets (Generic Luvox) Preparations

Fluvoxin Tablets (Fluvoxamine Maleate) Tablets are available in 25 mg, 50 mg and 100 mg tablets for oral administration.


Fluvoxin Tablets - Contraindications

The contraindications of Fluvoxin Tablets (Generic Luvox) are as follows:
Coadministration of tizanidine, thioridazine, alosetron, or pimozide with LUVOX Tablets is contraindicated.The use of MAOI's concomitantly with or within 14 days of treatment with LUVOX Tablets is contraindicated.


Fluvoxin Tablets - Storage Requirements

Fluvoxin Tablets (Generic Luvox) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.



Fluvoxin Tablets (Generic Luvox) - Uses

Generic Luvox in the form of Fluvoxin Tablets is used to treat obsessions and compulsions in patients with obsessive compulsive disorder (OCD). Fluvoxin Tablets (Fluvoxamine Maleate) is also prescribed to treat major depressive disorder (MDD) and anxiety disorders, such as generalized anxiety disorder (GAD), panic disorder, and post-traumatic stress disorder (PTSD).



Fluvoxin Tablets - Dosage

The recommended starting dose of Fluvoxin Tablets for Adults is 50 mg at bedtime, with increases of 50 mg every 4 to 7 days as tolerated until maximum therapeutic effect is obtained. Dosage is not to exceed 300 mg/day. The Daily doses over 100mg should be divided. When discontinuing Generic Luvox Gradual dose reduction is recommended. Please consult your doctor for exact dosing instructions.



Side Effects Of Fluvoxin Tablets (Generic Luvox)

The most common side effects of are nausea, somnolence, insomnia, asthenia, nervousness, dyspepsia, abnormal ejaculation, sweating ,anorexia, tremor, and vomiting. Other side effects that may occur are anorgasmia, decreased libido, dry mouth, rhinitis, taste perversion, and urinary frequency in patients with OCD; and agitation, depression, dysmenorrhea, flatulence, hyperkinesia, and rash in pediatric patients with OCD.


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Thursday, August 11, 2011

Pramipex Tablets | Generic Mirapex | Dosage | Uses | Side effects

Pramipex Tablets (Generic Mirapex) - Active Ingredient And Chemical structure

The active ingredient contained in Pramipex Tablets is Pramipexole Dihydrochloride. Pramipexole dihydrochloride is a white to off-white powder that is more than 20% soluble in water. The structure is shown below
Structure Of Pramipexole


Generic Forms and Brand names of Mirapex (Pramipexole Dihydrochloride)

Pramipex Tablets manufactured by SUN Pharmaceuticals, India is an effective treatment for idiopathic Parkinson's disease and moderate-to-severe primary Restless Legs Syndrome (RLS). Mirapex which has the active ingredient Pramipexole Dihydrochloride is also sold as Pramipexin, Sifrol and under various other brand names.


Pramipex Tablets (Generic Mirapex) - Preparations

Pramipex Tablets is available as tablets of 0.125 mg, 0.25 mg, 0.5 mg, 1 mg and 1.5 mg. Pramipex Tablets for oral administration, contain 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, or 1.5 mg of pramipexole dihydrochloride monohydrate.


Pramipex Tablets (Generic Mirapex) - Storage Requirements

Pramipex Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Mirapex (Pramipexole Dihydrochloride) - Uses

Generic Mirapex (Pramipexole Dihydrochloride) in the form of Pramipex Tablets is used to treat the signs and symptoms of idiopathic Parkinson's disease and for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).


Pramipex Tablets (Generic Mirapex) - Contraindications

Pramipex Tablets are contraindicated in patients who have demonstrated hypersensitivity to Pramipexole Dihydrochloride or any of the inactive ingredients.


Pramipex Tablets (Generic Mirapex) - Dosage

For the treatment of Parkinson's disease the recommended starting dose is 0.375 mg/day given in three divided doses and should not be increased more frequently than every 5 to 7 days. For maintenance treatment Pramipex Tablets (pramipexole dihydrochloride) were effective and well tolerated over a dosage range of 1.5 to 4.5 mg/day administered in equally divided doses three times per day. In the case of Restless Legs Syndrome the recommended starting dose of Pramipex Tablets is 0.125 mg taken once daily 2 to 3 hours before bedtime.


Side Effects Of Pramipex Tablets (Generic Mirapex)

The most common side effects of are Pramipex Tablets nausea, dizziness, somnolence, insomnia, constipation, asthenia, and hallucinations.


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Tuesday, August 9, 2011

Attentrol Capsules | Generic Strattera | Dosage | Uses | Side effects

Attentrol Capsules (Generic Strattera) - Active Ingredient And Chemical structure

The active ingredient contained in Attentrol Capsules is Atomoxetine Hydrochloride . Atomoxetine HCl is a white to practically white solid, which has a solubility of 27.8 mg/mL in water. The structure is shown below

Structure Of Atomoxetine Hydrochloride


Attentrol Capsules (Generic Strattera)- Uses

Atomoxetine Hydrochloride in the form of Generic Strattera Capsules (Attentrol Capsules) is a selective norepinephrine reuptake inhibitor used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).


Generic Forms and Brand names of Strattera (Atomoxetine Hydrochloride)

Attentrol manufactured by Sun Pharmaceutical Industries Ltd., India is an effective treatment for treatment of Attention Deficit Hyperactivity Disorder (ADHD). Strattera which has the active ingredient Atomoxetine Hydrochloride is also sold as Attentin, Tomoxetin and under various other brand names. Strattera (Atomoxetine HCl) is a selective norepinephrine reuptake inhibitor.


Attentrol Capsules (Generic Strattera) - Preparations

Attentrol is available as Capsules of 10 mg, 18 mg, 25 mg, 40 mg, 60 mg, 80 mg and 100 mg. Each capsule contains atomoxetine HCl equivalent to 10, 18, 25, 40, 60, 80, or 100 mg of atomoxetine.


Attentrol Capsules (Generic Strattera) - Storage Requirements

Attentrol Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Attentrol Capsules (Generic Strattera) - Contraindications

Attentrol Capsules are contraindicated in the following cases:
Hypersensitivity to Atomoxetine HCl or other constituents of product. Use of Attentrol Capsules within 2 weeks after discontinuing MAOI or other drugs that affect brain monoamine concentrations. In patients with Narrow Angle Glaucoma.


Attentrol Capsules (Generic Strattera) - Dosage

The recommended starting dose of Attentrol Capsules for adults as well as Children and adolescents over 70 kg is 40 mg once a day.


Warnings And Precautions When Using Attentrol Capsules (Generic Strattera)


Suicidal Ideation - Monitor for suicidality, clinical worsening, and unusual changes in behavior.
Severe Liver Injury - Attentrol Capsules should be discontinued and not restarted in patients with jaundice or laboratory evidence of liver injury.
Serious Cardiovascular Events - Sudden death, stroke and myocardial infarction have been reported in association with atomoxetine treatment. Generic Strattera generally should not be used in children or adolescents with known serious structural cardiac abnormalities, cardiomyopathy, serious heart rhythm bnormalities, or other serious cardiac problems. Consideration has be given to not using Generic Strattera in adults with clinically significant cardiac abnormalities.
Emergent Cardiovascular Symptoms - Patients should undergo prompt cardiac evaluation.
Effects on Blood Pressure and Heart Rate - Can increase blood pressure and heart rate; orthostasis, syncope and Raynaud's phenomenon may occur. Use with caution in patients with hypertension, tachycardia, or cardiovascular or cerebrovascular disease.
Emergent Psychotic or Manic Symptoms - Discontinuing treatment with Attentrol Capsules should be considered if such new Psychotic or Manic Symptoms symptoms occur.
Bipolar Disorder - Patients should be screened to avoid possible induction of a mixed/manic episode.
Aggressive behavior - Aggressive behavior or hostility in patients undergoing treatment should be monitored.
Possible allergic reactions - Possible allergic reactions including anaphylactic reactions, angioneurotic edema, urticaria, and rash can occur in patients undergoing Attentrol therapy.
Effects on Urine Outflow - Urinary hesitancy and retention may occur.
Priapism - Prompt medical attention is required in the event of suspected priapism.
Growth - Height and weight should be monitored in pediatric patients. Concomitant Use of Potent CYP2D6 Inhibitors or Use in patients known to be CYP2D6 PMs may require dose adjustment of Attentrol.


Side Effects Of Attentrol Capsules (Generic Strattera)

The most common side effects of Attentrol Capsules are:
Child and Adolescent Clinical Trials - Nausea, vomiting, fatigue, decreased appetite, abdominal pain, and somnolence.
Adult Clinical Trials - Constipation, dry mouth, nausea, fatigue, decreased appetite, insomnia, erectile dysfunction, urinary hesitation and/or urinary retention and/or dysuria, dysmenorrhea, and hot flush.
There have been rare cases of clinically significant liver injury that were considered probably or possibly related to Strattera use in postmarketing experience. Generic Strattera (Attentrol Capsules) should be discontinued in patients with jaundice or laboratory evidence of liver injury, and should not be restarted.


Further Information

Prescribing Information