Lanzol Capsules | Generic Prevacid | Lansoprazole | Dosage | Uses | Side effects

Lanzol Capsules (Generic Prevacid) - Active Ingredient And Chemical structure

The active ingredient contained in Lanzol Capsules is Lansoprazole. Lansoprazole is a white to brownish white odorless crystalline powder which melts with decomposition at approximately 166°C. Lansoprazole is freely soluble in dimethylformamide; soluble in methanol; sparingly soluble in ethanol; slightly soluble in ethyl acetate, dichloromethane and acetonitrile; very slightly soluble in ether; and practically insoluble in hexane and water. The structure is shown below

Generic Forms and Brand names of Generic Prevacid (Generic Prevacid)

Lanzol Capsule manufactured by Cipla Ltd., India is an effective treatment for used to treat and prevent Duodenal Ulcer and gastric ulcers, Gastroesophageal Reflux Disease (GERD),erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Prevacid which has the active ingredient Lansoprazole is also sold as and under various other brand names.

Lanzol Capsules (Lansoprazole) - Uses

Lansoprazole in the form of Generic Prevacid Capsules (Lanzol Capsules) is used in the treatment of the below listed indications:
Short-Term Treatment of Active Duodenal Ulcer
Lanzol is indicated for short-term treatment (up to 4 weeks) for healing and symptom relief of active duodenal ulcer.
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Lanzol in combination with amoxicillin plus clarithromycin as triple therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.
Lanzol in combination with amoxicillin as dual therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected.
Maintenance of Healed Duodenal Ulcers
Lanzol is indicated to maintain healing of duodenal ulcers. Controlled studies do not extend beyond 12 months.
Short-Term Treatment of Active Benign Gastric Ulcer
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of active benign gastric ulcer.
Healing of NSAID-Associated Gastric Ulcer
Lanzol is indicated for the treatment of NSAID-associated gastric ulcer in patients who continue NSAID use. Controlled studies did not extend beyond 8 weeks.
Risk Reduction of NSAID-Associated Gastric Ulcer
Lanzol is indicated for reducing the risk of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID. Controlled studies did not extend beyond 12 weeks.
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD
Lanzol is indicated for the treatment of heartburn and other symptoms associated with GERD.
Short-Term Treatment of Erosive Esophagitis
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of all grades of erosive esophagitis. For patients who do not heal with Lanzol for 8 weeks (5-10%), it may be helpful to give an additional 8 weeks of treatment. If there is a recurrence of erosive esophagitis an additional 8-week course of Lanzol may be considered.
Maintenance of Healing of Erosive Esophagitis
Lanzol is indicated to maintain healing of erosive esophagitis. Controlled studies did not extend beyond 12 months.
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome
Lanzol is indicated for the long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome.

Lanzol Capsules (Generic Prevacid) - Preparations

Lanzol Capsules(Lansoprazole) is available as tablets of 15 mg and 30 mg .

Lanzol Capsules (Generic Prevacid) - Storage Requirements

Lanzol Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Lanzol Capsules - Dosage

The recommended dosage of Lanzol Capsules (Generic Prevacid) for variuous indications is given below:

Indication	Recommended Adult Dose	Frequency
Duodenal Ulcers
Short-Term Treatment	15 mg	Once daily for 4 weeks
Maintenance of Healed	15 mg	Once daily
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Triple Therapy
Lanzol	30 mg	Twice daily (q12h) for 10 or 14 days
Amoxicillin	1 gram	Twice daily (q12h) for 10 or 14 days
Clarithromycin	500 mg	Twice daily (q12h) for 10 or 14 days
Dual Therapy:
Lanzol	30 mg	Three times daily (q8h) for 14 days
Amoxicillin	1 gram	Three times daily (q8h) for 14 days
Benign Gastric Ulcer
Short-Term Treatment	30 mg	Once daily for up to 8 weeks
NSAID-associated Gastric Ulcer
Healing	30 mg	Once daily for 8 weeks
Risk Reduction	15 mg	Once daily for up to 12 weeks
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD	15 mg	Once daily for up to 8 weeks
Short -Term Treatment of Erosive Esophagitis	30 mg	Once daily for up to 8 weeks

Side Effects Of Lanzol

The most common side effects of are Abdominal Pain, Constipation, Diarrhea, Nausea. There are also some rarely occuring side effects that may occur in less than 1% of the patients undergoing Lanzol therapy.

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Zinetac Tablets | Generic Zantac | Dosage | Uses | Side effects

Zinetac Tablets (Generic Zantac) - Active Ingredient And Chemical structure

The active ingredient contained in Zinetac Tablets is Ranitidine Hydrochloride. Ranitidine HCl is a white to pale yellow, granular substance that is soluble in water. It has a slightly bitter taste and sulfur like odour.The structure is shown below

Generic Zantac (Ranitidine HCl) - Uses

Generic Zantac in the form of Zinetac Tablets is used for the:
1.Short term treatment of active duodenal ulcer. Most patients undergoing treatment heal within 4 weeks of Zinetac therapy.
2.Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.
3.The treatment of pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome and systemic mastocytosis).
4.Short term treatment of active, benign gastric ulcer. Most patients undergoing treatment heal within 6 weeks.
5. Maintenance therapy for gastric ulcer patients at reduced dosage after healing of acute ulcers.
6. Treatment of GERD. Symptomatic relief commonly occurs within 24 hours after starting therapy with Zinetac 150 mg twice a day.
7. Treatment of endoscopically diagnosed erosive esophagitis. Symptomatic relief of heartburn commonly occurs within 24 hours of therapy initiation with Zinetac 150 mg four times a day.
8. Maintenance of healing of erosive esophagitis.
Concomitant antacids should be given as needed for pain relief to patients with active duodenal ulcer; active, benign gastric ulcer; hypersecretory states; GERD; and erosive esophagitis.

Generic Forms and Brand names of Zantac (Ranitidine HCl)

Zinetac Tablets manufactured by GlaxoSmithKline, India is an effective treatment for the conditions that cause your body to make too much stomach acid. Zantac which has the active ingredient Ranitidine Hydrochloride is also sold under various other brand names.

Zinetac Tablets (Generic Zantac) - Preparations

Zinetac Tablets is available as tablets of 150 mg and 300 mg . Each Zinetac 150 mg Tablet for oral administration contains 168 mg of ranitidine HCl equivalent to 150 mg of ranitidine.

Zinetac Tablets (Generic Zantac) - Storage Requirements

Zinetac Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.

Zinetac Tablets (Generic Zantac) - Dosage

The recommended dosage for the various conditions being treated is given below. Please consult your doctor for exact dosing instructions.
Active Duodenal Ulcer: The recommended adult oral dosage of Zinetac Tablets for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The recommended adult oral dosage is 150 mg twice a day.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice a day.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice a day.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg 4 times a day.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice a day.

Zinetac Tablets (Generic Zantac) - Contraindications

Zinetac Tablets is contraindicated for patients known to have hypersensitivity to Ranitidine Hydrochloride or any inactive ingredient present in the medication.

Side Effects Of Zinetac Tablets (Generic Zantac)

The most common side effects of Zinetac Tablets (Ranitidine HCl) are
Central Nervous System: Rarely, malaise, dizziness, somnolence, insomnia, and vertigo. Rare cases of reversible mental confusion, agitation, depression, and hallucinations have been reported, predominantly in severely ill elderly patients. Rare cases of reversible blurred vision as well as of reversible involuntary motor disturbances have also been received.
Cardiovascular: As with other H2-blockers, rare reports of arrhythmias such as tachycardia, bradycardia, atrioventricular block, and premature ventricular beats.
Gastrointestinal: Constipation, diarrhea, nausea/vomiting, abdominal discomfort/pain, and rare reports of pancreatitis.
Hepatic: There have been occasional reports of hepatocellular, cholestatic, or mixed hepatitis, with or without jaundice. In such circumstances, ranitidine should be immediately discontinued. These events are usually reversible, but in rare circumstances death has occurred. Rare cases of hepatic failure have also been reported.
Musculoskeletal: Rare reports of arthralgias and myalgias.
Hematologic: Blood count changes (leukopenia, granulocytopenia, and thrombocytopenia) that were usually reversible have occurred in a few patients. There were rare cases of agranulocytosis, pancytopenia, sometimes with marrow hypoplasia, and aplastic anemia and exceedingly rare cases of acquired immune hemolytic anemia that have been reported.
Endocrine: Controlled studies in animals and man have shown no stimulation of any pituitary hormone by Ranitidine HCl and no antiandrogenic activity, and cimetidine-induced gynecomastia and impotence in hypersecretory patients have resolved when Zinetac has been substituted. However, occasional cases of gynecomastia, impotence, and loss of libido have been reported in male patients receiving Zinetac , but the incidence did not differ from that in the general population.
Integumentary: Rash, including rare cases of erythema multiforme. Rare cases of alopecia and vasculitis.
Other Side Effects: The other side effects reported with Zinetac (Ranitidine HCl) use are Rare cases of hypersensitivity reactions (e.g., bronchospasm, fever, rash, eosinophilia), anaphylaxis, angioneurotic edema, and small increases in serum creatinine.

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Evalon Tablets | Estriol | Ovestin | Dosage | Uses | Side effects

Evalon Tablets (Estriol) - Active Ingredient And Chemical structure

The active ingredient contained in Evalon Tablets is Estriol. Estriol is a white odorless crystalline powder with a melting point of 282&ndeg;C . It is insoluble in water, sparingly soluble in ethanol and completely soluble in acetone, dioxane, diethyl ether, and vegetable oils. The structure is shown below

Generic Forms and Brand names of Estriol (Ovestin)

Evalon Tablets manufactured by Organon, India (a subsidiary of Schering-Plough Corporation, Part of Merck & Co. Inc.) is an effective treatment for distressing symptoms during menopause. Ovestin which has the active ingredient Estriol is also sold as Lynoral and under various other brand names.

Evalon Tablets (Estriol) - Uses

Evalon Tablets are prescribed as Hormone replacement therapy (HRT) for menopausal symptoms due to the loss of oestrogen production in postmenopausal women . Estriol is also used for treating Infertility due to cervical hostility.

Evalon Tablets (Estriol) - Preparations

Evalon Tablets is available as tablets of 1 mg and 2 mg.

Evalon Tablets (Estriol) - Storage Requirements

Evalon Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Evalon Tablets (Estriol) - Dosage

Treatment of estrogen deficiency symptoms:
The recommended dosage is 4-8 mg per day during the first weeks, followed by a gradual reduction. The lowest effective dosage of Estriol should be used. In case of long term Evalon therapy in women with an intact uterus, monitoring of the endometrium or, alternatively, concomitant use of a progestagen is recommended.
Infertility due to cervical hostility:
The recommended dosage in general is 1-2 mg per day on days 6-15 of the menstrual cycle. However, for some patients dosages as low as 1 mg per day are sufficient, whereas others may need up to 8 mg per day. Therefore, the dosage should be increased each month until an optimal effect on the cervical mucus is obtained.
Please consult your doctor for your exact dosing schedule.

Evalon Tablets (Estriol) - Contraindications

Hypersensitivity to the active ingredient Estriol or any other inactive ingredient present in Evalon Tablets
Known, past or suspected breast cancer
Known or suspected estrogen-dependent malignant tumors (e.g. endometrial cancer)
Undiagnosed genital bleeding
Untreated endometrial hyperplasia
Previous idiopathic or current venous thromboembolism (deep venous thrombosis, pulmonary embolism)
Active or recent arterial thromboembolic disease (e.g. angina, myocardial infarction)
Acute liver disease, or a history of liver disease as long as liver function tests failed to return to normal
Porphyria (Rare inherited disorders in which an important part of hemoglobin, called heme, is not made properly)
Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption

Side Effects Of Evalon Tablets (Estriol)

The most common side effects of Estriol are Breast discomfort and pain,Postmenopausal spotting,Cervical discharge,Nausea and Fluid retention. Estriol Therapy should be discontinued if any of the following situations arise: Jaundice or deterioration in liver function, Significant increase in blood pressure, New onset of migraine-type headache, Pregnancy or Endometrial hyperplasia.