T-Bact Ointment | Generic Bactroban Cream | Dosage | Uses | Side effects

T-Bact Ointment (Generic Bactroban Cream) - Active Ingredient And Chemical structure

The active ingredient contained in T-Bact Ointment is Mupirocin. Mupirocin is a naturally occurring antibiotic. The structure is shown below

T-Bact Ointment (Generic Bactroban Cream) - Uses

Generic Bactroban Cream in the form of T-Bact Ointment is used for the topical treatment of impetigo due to S. aureus and S. pyogenes.

Generic Forms and Brand names of Bactroban Cream

T-Bact Ointment manufactured by GlaxoSmithKline, India is an effective treatment for impetigo and small wounds which have become infected. These wounds may include small cuts and abrasions or stitches. Bactroban Cream which has the active ingredient Mupirocin is also sold as Centany and under various other brand names.

T-Bact Ointment - Preparations

T-Bact Ointment is available as 5 g tubes containing Mupirocin USP 2.0% w/w. Each gram of T-Bact Ointment (mupirocin ointment, 2%) contains 20 mg mupirocin in a bland water miscible ointment base.

T-Bact Ointment (Generic Bactroban Cream) - Contraindications

T-Bact Ointment is contraindicated in individuals with a history of sensitivity reactions to Mupirocin or any of its inactive ingredients.

T-Bact Ointment (Generic Bactroban Cream) - Storage Requirements

T-Bact Ointment is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

T-Bact Ointment - Dosage

A small amount of T-Bact Ointment should be applied to the affected area three times daily. The area under treatment can be covered with a gauze dressing if desired.

T-Bact Ointment - Pediatric Use

The safety and effectiveness of T-Bact Ointment (mupirocin ointment, 2%) have been established in the age range of 2 months to 16 years. The use of Mupirocin ointment in these age groups is supported by evidence from adequate and well-controlled studies of Bactroban ointment in impetigo in pediatric patients.

T-Bact Ointment - Precautions

If a reaction takes place that suggests sensitivity or chemical irritation occurs with the use of T-Bact Ointment treatment should be discontinued and appropriate alternative therapy for the infection should be instituted. As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi.

Side Effects Of T-Bact Ointment (Generic Bactroban Cream)

The most common side effects of T-Bact Ointment are Burning, stinging, or pain in 1.5% of patients; itching in 1% of patients; rash, nausea, erythema, dry skin, tenderness, swelling, contact dermatitis, and increased exudate in less than 1% of patients. Systemic reactions to T-Bact Ointment have rarely occurred.

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Acetec Capsules | Generic Soriatane | Dosage | Uses | Side effects

Acetec Capsules (Generic Soriatane) - Active Ingredient And Chemical structure

The active ingredient contained in Acetec Capsules (Generic Soriatane) is Acitretin, a retinoid. Acitretin is a yellow to greenish-yellow powder with a molecular weight of 326.44. The structure is shown below

Acetec Capsules (Generic Soriatane) - Uses

Generic Soriatane in the form of Acetec Capsules is used to treat severe psoriasis in adults. As there exists significant adverse effects associated with its use, Soriatane should be prescribed only by those knowledgeable in the systemic use of retinoids. In the case of females of reproductive potential,
Soriatane should be administered only to non-pregnant patients who are not responsive to other medications or whose clinical condition contraindicates the use of other treatments.

Generic Forms and Brand names of Soriatane

Acetec Capsules manufactured by Dr Reddy's Laboratories Ltd., India is an effective treatment for severe resistant psoriasis in adults. Soriatane which has the active ingredient Acitretin is also sold as Generic Acitretin, Soriatane, Aceret or Acitrin and under various other brand names.

Acetec Capsules - Preparations

Acetec is available as Capsules of 10 mg and 25 mg for oral administration.

Acetec Capsules (Generic Soriatane) - Storage Requirements

Acetec Capsules (Generic Soriatane) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Acetec Capsules (Generic Soriatane) - Contraindications

Generic Soriatane must not be used by females who are pregnant, or who intend to become pregnant during therapy or at any time for at least 3 years following discontinuation of therapy.
Acetec Capsules (Generic Soriatane) is contraindicated in patients with severely impaired liver or kidney function and in patients with chronic abnormally elevated blood lipid values. An increased risk of hepatitis has been reported to result from combined use of methotrexate and etretinate. Consequently, the combination of methotrexate with Generic Soriatane is also contraindicated.
Similarly both Soriatane and tetracyclines can cause increased intracranial pressure, their combined use is contraindicated. Acetec Capsules (Generic Soriatane) is contraindicated in cases of hypersensitivity to acitretin or any inactive ingredient present in the medication or to other retinoids.

Acetec Capsules (Generic Soriatane) - Dosage

Acetec Capsules therapy should be initiated for adults at 25 to 50 mg per day, given as a single dose with the main meal. Maintenance doses of 25 to 50 mg per day may be given dependent upon an individual patient’s response to initial treatment. Relapses may be treated as outlined for initial therapy.

Side Effects Of Acetec Capsules (Generic Soriatane)

Hypervitaminosis A produces a wide spectrum of signs and symptoms primarily of the mucocutaneous, musculoskeletal, hepatic, neuropsychiatric, and central nervous systems. Many of the clinical adverse reactions reported to date with Generic Soriatane administration resemble those of the hypervitaminosis A syndrome. The side effects of Acetec Capsules (Generic Soriatane) are listed below:
Cardiovascular: Acute myocardial infarction, thromboembolism, stroke
Nervous System: Myopathy with peripheral neuropathy has been reported during Soriatane therapy. Both conditions improved with discontinuation of the drug.
Psychiatric: Aggressive feelings and/or suicidal thoughts have been reported. These events, including self-injurious behavior, have been reported in patients taking other systemically administered retinoids, as well as in patients taking Soriatane.
Reproductive: Vulvo-vaginitis due to Candida albicans
Skin and Appendages: Thinning of the skin, skin fragility and scaling may occur all over the body, particularly on the palms and soles; nail fragility is frequently observed.
The other reported side effects include:
Central Nervous System
Rigors
Eye Disorders
Xerophthalmia
Mucous Membranes
Cheilitis, Rhinitis, Dry mouth, Epistaxis
Musculoskeletal
Arthralgia
Spinal hyperostosis(progression of existing lesions)
Skin and Appendages
Alopecia, Dry skin, Erythematous rash, Skin peeling, Nail disorder, Hyperesthesia, Pruritus, Paresthesia, Paronychia,Skin atrophy, Sticky skin

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E2 Vaginal Tablets | Generic Vagifem Pessaries | Dosage | Uses | Side effects

E2 Vaginal Tablets (Generic Vagifem Pessaries) - Active Ingredient And Chemical structure

The active ingredient contained in Generic Vagifem Pessaries is Estradiol ( also referred to as oestradiol). Oestradiol which is in Vagifem is a natural type of oestrogen. Estradiol hemihydrate is a white, almost white or colorless crystalline solid. The structure is shown below

E2 Vaginal Tablets (Generic Vagifem) - Uses

Generic Vagifem in the form of E2 Vaginal Tablets is used for the treatment of certain vaginal symptoms which occur after menopause, such as dryness, itchiness and pain during sexual intercourse. This is caused by a drop in the level of a hormone called oestrogen. However, your doctor may prescribe this medicine for another use.

Generic Forms and Brand names of Vagifem Pessaries

E2 Vaginal Tablets manufactured by Sun Pharmaceuticals Ltd., India is an effective treatment for vaginal conditions caused by menopause or a deficiency of estrogen hormone. Vagifem which has the active ingredient Estradiol is also sold as Vagifem Suppository, Estradiol, Estrace, Estring, Femring, Estring Ring and under various other brand names.

E2 Vaginal Tablets - Preparations

E2 Vaginal Tablets are available as tablets of 2 mg.

E2 Vaginal Tablets (Generic Vagifem) - Contraindications

E2 Vaginal Tablets (Generic Vagifem) should not be used in women with any of the following conditions:
(1)Known allergy to oestradiol or any inactive ingredient present in Generic Vagifem
(2)Undiagnosed abnormal genital bleeding
(3)Known, suspected, or history of breast cancer
(4)Known or suspected estrogen-dependent neoplasia
(5)Active deep vein thrombosis, pulmonary embolism or history of these conditions
(6)Active arterial thromboembolic disease (for example, stroke, and myocardial infarction), or a history of these conditions
(7)Known liver dysfunction or disease
(8) Known or suspected pregnancy

E2 Vaginal Tablets (Generic Vagifem) - Storage Requirements

E2 Vaginal Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

E2 Vaginal Tablets (Generic Vagifem) - Warnings and Precautions

The warnings and precautions to be taken when using E2 Vaginal Tablets (Generic Vagifem) are given below:
Estrogens increase the risk of gallbladder disease
Discontinue estrogen if severe hypercalcemia, loss of vision, severe hypertriglyceridemia or cholestatic jaundice occurs
The Vagifem applicator may cause vaginal abrasion
Monitor thyroid function in women on thyroid replacement therapy

E2 Vaginal Tablets (Generic Vagifem) - Dosage

E2 Vaginal Tablets (Generic Vagifem) should be administered intravaginally. The recommended dose is 1 tablet daily for 2 weeks, followed by 1 tablet twice weekly.

Side Effects Of E2 Vaginal Tablets (Generic Vagifem)

The most common side effects of E2 Vaginal Tablets (Generic Vagifem) with an incidence rate of 5% or greater are upper respiratory tract infection, headache, abdominal pain, back pain, genital pruritis, moniliasis, vulvovaginal mycotic infection and diarrhea.

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