Penegra Tablets | Sildenafil Citrate | Dosage | Penegra Side effects

Penegra Tablets (Generic Viagra) - Active Ingredient And Chemical structure

Generic Viagra is an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). The active ingredient contained in Penegra tablets is Sildenafil citrate .Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water. The structure is shown below

Generic Forms and Brand names of Viagra (Sildenafil citrate)

Penegra manufactured by Zydus Cadila, India is an effective treatment for erectile dysfunction, also known as male impotence .Viagra which has the active ingredient Sildenafil citrate is also sold as Kamagra, Caverta, Silagra, Revatio and under various other brand names.

Penegra Tablets (Sildenafil citrate) - Uses

Sildenafil citrate in the form of Penegra Tablets is used to treat erectile dysfunction, also known as male impotence. Penegra is rapidly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes of oral dosing in the fasted state. When Penegra is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in Time to reach maximum concentration of 60 minutes and a mean reduction in Concentration of 29%.

Penegra Tablets (Sildenafil citrate)- Preparations

Penegra is available as tablets of 25 mg, 50 mg and 100 mg . Each tablet of penegra (sildenafil citrate) is equivalent to 25 mg, 50 mg and 100 mg of sildenafil respectively for oral administration.

Penegra Tablets (Sildenafil citrate) - Storage Requirements

Penegra Tablets are to be stored at room temperature (25°C to 30°C). Store away from heat, moisture, and light.

Penegra Tablets - Dosage

For most patients, the recommended dose of Penegra is 50 mg taken, as needed, approximately 1 hour before sexual activity. Penegra may however be taken anywhere from 4 hours to half an hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum of 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once a day.

Penegra Tablets (Sildenafil citrate) - Contraindications

Penegra is contraindicated in patients with a known hypersensitivity to Sildenafil citrate or to any inactive component of the tablet. Penegra (Sildenafil citrate) was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using organic nitrates, either regularly and/or intermittently, in any form is therefore contraindicated. There is a potential for cardiac risk of sexual activity in patients with preexisting cardiovascular disease. Therefore, treatments for erectile dysfunction, including Sildenafil citrate, should not be generally used in men for whom sexual activity is inadvisable because of their underlying cardiovascular status.

Side Effects Of Penegra Tablets (Sildenafil citrate)

The most common side effects of Penegra are Headache, Flushing,Dyspepsia, Nasal Congestion, Urinary Tract Infection, Abnormal Vision (Mild and transient, predominantly color tinge to vision, but also increased sensitivity to light or blurred vision), Diarrhea, Dizziness and Rash.

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Lanzol Capsules | Generic Prevacid | Lansoprazole | Dosage | Uses | Side effects

Lanzol Capsules (Generic Prevacid) - Active Ingredient And Chemical structure

The active ingredient contained in Lanzol Capsules is Lansoprazole. Lansoprazole is a white to brownish white odorless crystalline powder which melts with decomposition at approximately 166°C. Lansoprazole is freely soluble in dimethylformamide; soluble in methanol; sparingly soluble in ethanol; slightly soluble in ethyl acetate, dichloromethane and acetonitrile; very slightly soluble in ether; and practically insoluble in hexane and water. The structure is shown below

Generic Forms and Brand names of Generic Prevacid (Generic Prevacid)

Lanzol Capsule manufactured by Cipla Ltd., India is an effective treatment for used to treat and prevent Duodenal Ulcer and gastric ulcers, Gastroesophageal Reflux Disease (GERD),erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Prevacid which has the active ingredient Lansoprazole is also sold as and under various other brand names.

Lanzol Capsules (Lansoprazole) - Uses

Lansoprazole in the form of Generic Prevacid Capsules (Lanzol Capsules) is used in the treatment of the below listed indications:
Short-Term Treatment of Active Duodenal Ulcer
Lanzol is indicated for short-term treatment (up to 4 weeks) for healing and symptom relief of active duodenal ulcer.
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Lanzol in combination with amoxicillin plus clarithromycin as triple therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.
Lanzol in combination with amoxicillin as dual therapy is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or one-year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected.
Maintenance of Healed Duodenal Ulcers
Lanzol is indicated to maintain healing of duodenal ulcers. Controlled studies do not extend beyond 12 months.
Short-Term Treatment of Active Benign Gastric Ulcer
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of active benign gastric ulcer.
Healing of NSAID-Associated Gastric Ulcer
Lanzol is indicated for the treatment of NSAID-associated gastric ulcer in patients who continue NSAID use. Controlled studies did not extend beyond 8 weeks.
Risk Reduction of NSAID-Associated Gastric Ulcer
Lanzol is indicated for reducing the risk of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID. Controlled studies did not extend beyond 12 weeks.
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD
Lanzol is indicated for the treatment of heartburn and other symptoms associated with GERD.
Short-Term Treatment of Erosive Esophagitis
Lanzol is indicated for short-term treatment (up to 8 weeks) for healing and symptom relief of all grades of erosive esophagitis. For patients who do not heal with Lanzol for 8 weeks (5-10%), it may be helpful to give an additional 8 weeks of treatment. If there is a recurrence of erosive esophagitis an additional 8-week course of Lanzol may be considered.
Maintenance of Healing of Erosive Esophagitis
Lanzol is indicated to maintain healing of erosive esophagitis. Controlled studies did not extend beyond 12 months.
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome
Lanzol is indicated for the long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome.

Lanzol Capsules (Generic Prevacid) - Preparations

Lanzol Capsules(Lansoprazole) is available as tablets of 15 mg and 30 mg .

Lanzol Capsules (Generic Prevacid) - Storage Requirements

Lanzol Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Lanzol Capsules - Dosage

The recommended dosage of Lanzol Capsules (Generic Prevacid) for variuous indications is given below:

Indication	Recommended Adult Dose	Frequency
Duodenal Ulcers
Short-Term Treatment	15 mg	Once daily for 4 weeks
Maintenance of Healed	15 mg	Once daily
H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Triple Therapy
Lanzol	30 mg	Twice daily (q12h) for 10 or 14 days
Amoxicillin	1 gram	Twice daily (q12h) for 10 or 14 days
Clarithromycin	500 mg	Twice daily (q12h) for 10 or 14 days
Dual Therapy:
Lanzol	30 mg	Three times daily (q8h) for 14 days
Amoxicillin	1 gram	Three times daily (q8h) for 14 days
Benign Gastric Ulcer
Short-Term Treatment	30 mg	Once daily for up to 8 weeks
NSAID-associated Gastric Ulcer
Healing	30 mg	Once daily for 8 weeks
Risk Reduction	15 mg	Once daily for up to 12 weeks
Gastroesophageal Reflux Disease (GERD)
Short-Term Treatment of Symptomatic GERD	15 mg	Once daily for up to 8 weeks
Short -Term Treatment of Erosive Esophagitis	30 mg	Once daily for up to 8 weeks

Side Effects Of Lanzol

The most common side effects of are Abdominal Pain, Constipation, Diarrhea, Nausea. There are also some rarely occuring side effects that may occur in less than 1% of the patients undergoing Lanzol therapy.

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Zinetac Tablets | Generic Zantac | Dosage | Uses | Side effects

Zinetac Tablets (Generic Zantac) - Active Ingredient And Chemical structure

The active ingredient contained in Zinetac Tablets is Ranitidine Hydrochloride. Ranitidine HCl is a white to pale yellow, granular substance that is soluble in water. It has a slightly bitter taste and sulfur like odour.The structure is shown below

Generic Zantac (Ranitidine HCl) - Uses

Generic Zantac in the form of Zinetac Tablets is used for the:
1.Short term treatment of active duodenal ulcer. Most patients undergoing treatment heal within 4 weeks of Zinetac therapy.
2.Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers.
3.The treatment of pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome and systemic mastocytosis).
4.Short term treatment of active, benign gastric ulcer. Most patients undergoing treatment heal within 6 weeks.
5. Maintenance therapy for gastric ulcer patients at reduced dosage after healing of acute ulcers.
6. Treatment of GERD. Symptomatic relief commonly occurs within 24 hours after starting therapy with Zinetac 150 mg twice a day.
7. Treatment of endoscopically diagnosed erosive esophagitis. Symptomatic relief of heartburn commonly occurs within 24 hours of therapy initiation with Zinetac 150 mg four times a day.
8. Maintenance of healing of erosive esophagitis.
Concomitant antacids should be given as needed for pain relief to patients with active duodenal ulcer; active, benign gastric ulcer; hypersecretory states; GERD; and erosive esophagitis.

Generic Forms and Brand names of Zantac (Ranitidine HCl)

Zinetac Tablets manufactured by GlaxoSmithKline, India is an effective treatment for the conditions that cause your body to make too much stomach acid. Zantac which has the active ingredient Ranitidine Hydrochloride is also sold under various other brand names.

Zinetac Tablets (Generic Zantac) - Preparations

Zinetac Tablets is available as tablets of 150 mg and 300 mg . Each Zinetac 150 mg Tablet for oral administration contains 168 mg of ranitidine HCl equivalent to 150 mg of ranitidine.

Zinetac Tablets (Generic Zantac) - Storage Requirements

Zinetac Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.

Zinetac Tablets (Generic Zantac) - Dosage

The recommended dosage for the various conditions being treated is given below. Please consult your doctor for exact dosing instructions.
Active Duodenal Ulcer: The recommended adult oral dosage of Zinetac Tablets for duodenal ulcer is 150 mg twice daily.
Maintenance of Healing of Duodenal Ulcers: The recommended adult oral dosage is 150 mg at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The recommended adult oral dosage is 150 mg twice a day.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg twice a day.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg at bedtime.
GERD: The current recommended adult oral dosage is 150 mg twice a day.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg 4 times a day.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg twice a day.

Zinetac Tablets (Generic Zantac) - Contraindications

Zinetac Tablets is contraindicated for patients known to have hypersensitivity to Ranitidine Hydrochloride or any inactive ingredient present in the medication.

Side Effects Of Zinetac Tablets (Generic Zantac)

The most common side effects of Zinetac Tablets (Ranitidine HCl) are
Central Nervous System: Rarely, malaise, dizziness, somnolence, insomnia, and vertigo. Rare cases of reversible mental confusion, agitation, depression, and hallucinations have been reported, predominantly in severely ill elderly patients. Rare cases of reversible blurred vision as well as of reversible involuntary motor disturbances have also been received.
Cardiovascular: As with other H2-blockers, rare reports of arrhythmias such as tachycardia, bradycardia, atrioventricular block, and premature ventricular beats.
Gastrointestinal: Constipation, diarrhea, nausea/vomiting, abdominal discomfort/pain, and rare reports of pancreatitis.
Hepatic: There have been occasional reports of hepatocellular, cholestatic, or mixed hepatitis, with or without jaundice. In such circumstances, ranitidine should be immediately discontinued. These events are usually reversible, but in rare circumstances death has occurred. Rare cases of hepatic failure have also been reported.
Musculoskeletal: Rare reports of arthralgias and myalgias.
Hematologic: Blood count changes (leukopenia, granulocytopenia, and thrombocytopenia) that were usually reversible have occurred in a few patients. There were rare cases of agranulocytosis, pancytopenia, sometimes with marrow hypoplasia, and aplastic anemia and exceedingly rare cases of acquired immune hemolytic anemia that have been reported.
Endocrine: Controlled studies in animals and man have shown no stimulation of any pituitary hormone by Ranitidine HCl and no antiandrogenic activity, and cimetidine-induced gynecomastia and impotence in hypersecretory patients have resolved when Zinetac has been substituted. However, occasional cases of gynecomastia, impotence, and loss of libido have been reported in male patients receiving Zinetac , but the incidence did not differ from that in the general population.
Integumentary: Rash, including rare cases of erythema multiforme. Rare cases of alopecia and vasculitis.
Other Side Effects: The other side effects reported with Zinetac (Ranitidine HCl) use are Rare cases of hypersensitivity reactions (e.g., bronchospasm, fever, rash, eosinophilia), anaphylaxis, angioneurotic edema, and small increases in serum creatinine.

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