Saturday, December 10, 2011

Indocap Capsules | Generic Indocin | Dosage | Uses | Side effects

Indocap Capsules (Generic Indocin) - Active Ingredient And Chemical structure

The active ingredient contained in Indocap Capsules is Indomethacin. Indomethacin is practically insoluble in water and sparingly soluble in alcohol. The structure is shown below

Structure Of Indomethacin


Generic Indocin - Uses

Generic Indocin in the form of Indocap Capsules is used to treat the following:
1.Moderate to severe rheumatoid arthritis including acute flares of chronic disease.
2. Moderate to severe ankylosing spondylitis.
3. Moderate to severe osteoarthritis.
4. Acute painful shoulder (bursitis and/or tendinitis).



Generic Forms and Brand names of Indocin

Indocap Capsules manufactured by Jagsonpal Pharmaceuticals Limited, India is an effective treatment for moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Indocin which has the active ingredient Indomethacin is also sold as Indocid, Indochro and under various other brand names.


Indocap Capsules - Preparations

Indocap is available as Capsules of 25 mg and 75 mg .


Indocap Capsules - Storage Requirements

Indocap Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Indocap Capsules - Contraindications

Indocap Capsules (Indomethacin) capsules are contraindicated in patients with known hypersensitivity to indomethacin or any inactive ingredient present in Indocap capsules.
Indomethacin extended-release capsules should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients. Indocap Capsules (Indomethacin) are contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.


Indocap Capsules - Dosage

The initial dosage of Indomethacin capsules (Indocap Capsules) is 25 mg twice a day or thrice a day. If this is well tolerated, the daily dosage may be increased by 25 or by 50 mg, if required, at weekly intervals until a satisfactory response is obtained or until a total daily dose of 150 to 200 mg is reached. Please consult your doctor for exact dosing instructions. The dosage is individualized.


Side Effects Of Indocap Capsules (Generic Indocin)

The most common side effects of are stomach pain, constipation, diarrhea gas, heartburn, nausea, vomiting, dizziness . Serious side effects that may occur are heart attack, stroke, high blood pressure, heart failure from body swelling (fluid retention), kidney problems including kidney failure,bleeding and ulcers in the stomach and intestine low red blood cells (anemia), life-threatening skin reactions, life-threatening allergic reactions, liver problems including liver failure and asthma attacks in people who have asthma.


Further Information

Additional Info: Prescribing Information

Friday, December 9, 2011

Naprosyn Tablets | Generic Aleve | Dosage | Uses | Side effects

Naprosyn Tablets (Generic Aleve) - Active Ingredient And Chemical structure

The active ingredient contained in Naprosyn Tablets is Naproxen Sodium. Naproxen is an odorless, white to off-white crystalline substance. It is lipid soluble, practically insoluble in water at low pH and freely soluble in water at high pH.. The structure is shown below

Structure Of Naproxen


Generic Forms and Brand names of Aleve (Naproxen Sodium)

Naprosyn Tablets are manufactured by RPG Lifesciences Ltd., India under license of F. Hoffmann- La Roche Ltd. Switzerland. Aleve which has the active ingredient is also sold as Anaprox Naprelan. Antalgin, Feminax Ultra, Flanax, Inza, Midol Extended Relief, Miranax, Nalgesin,Naposin, Naprogesic, Naprosyn, Narocin, Proxen, Synflex, Xenobid and under various other brand names.


Generic Aleve (Naprosyn Tablets) - Uses

Generic Aleve in the form of Naprosyn Tablets is used to treat signs and symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and juvenile arthritis.


Naprosyn Tablets (Generic Aleve) - Preparations

Naprosyn is available as tablets of 250 mg, 375 mg and 500 mg for oral administration.


Naprosyn Tablets (Generic Aleve) - Storage Requirements

Naprosyn Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Naprosyn Tablets - Dosage

The lowest effective dose for the shortest possible duration should be used. After observing the response to initial therapy with Naprosyn Tablets, the dose and frequency should be adjusted to suit an individual patient’s needs. For the treatment of Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis the adult dose is 250 mg or 375 mg or 500 mg twice daily.


Side Effects Of Naprosyn Tablets (Generic Aleve)

The most common side effects of are stomach pain, constipation, diarrhea, gas, heartburn, nausea, vomiting and dizziness.
Serious side effects include heart attack, stroke, high blood pressure, heart failure from body swelling (fluid retention), kidney problems including kidney failure, bleeding and ulcers in the stomach and intestine, low red blood cells (anemia), life-threatening skin reactions, life-threatening allergic reactions, liver problems including liver failure, asthma attacks in people who have asthma


Further Information

Additional Info: Prescribing Information

Saturday, December 3, 2011

Depo-Provera Contraceptive Injection | Dosage | Uses | Side effects

Depo-Provera Contraceptive Injection - Active Ingredient And Chemical structure

The active ingredient contained in Depo-Provera is medroxyprogesterone acetate, which is a a derivative of progesterone. Medroxyprogesterone acetate is a white to off-white odorless crystalline powder. It is freely soluble in chloroform, soluble in acetone and dioxane, sparingly soluble in alcohol and methanol, slightly soluble in ether, and insoluble in water. The structure is shown below
Structure Of Medroxyprogesterone acetate


Depo-Provera (Medroxyprogesterone Acetate) - Uses

Depo-Provera in the form of Depo-Provera Contraceptive Injection is used for the prevention of pregnancy. Depo-Provera is also used as adjunctive therapy and palliative treatment of inoperable, recurrent, and metastatic endometrial or renal carcinoma.


Generic Forms and Brand names of Depo-Provera (Medroxyprogesterone Acetate)

Depo-Provera Contraceptive Injection manufactured by Pfizer, Belgium is an effective treatment for the prevention of pregnancy.


Depo-Provera Contraceptive Injection - Preparations

Depo-Provera for intramuscular (IM) injection is available in vials and prefilled syringes. Each vial contains 1 mL of medroxyprogesterone acetate sterile aqueous suspension 150 mg/mL.


Depo-Provera Contraceptive Injection - Contraindication

Depo-Provera is contraindicated in known or suspected cases pregnancy or if the patient has known hypersensitivity to medroxyprogesterone acetate or any other inactive ingredients present in Depo-Provera. It is also contraindicated in patients that have active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease. Other cases where Depo-Provera is contrindicated include Known or suspected malignancy of breast, Significant liver disease and Undiagnosed vaginal bleeding.


Depo-Provera Contraceptive Injection - Storage Requirements

Depo-Provera Contraceptive Injection is be stored upright at controlled room temperature at (20°C to 25°C). Store away from heat, moisture, and light.


Warnings and Precautions When Using Depo-Provera Contraceptive Injection

Below are mentioned the warnings and precautions when Using Depo-Provera Contraceptive Injection:
Depo-Provera Contraceptive Injection (CI) use reduces serum estrogen levels and is associated with significant loss of bone mineral density (BMD).
Depo-Provera CI should be discontinued in patients who develop thrombosis
Women with breast nodules or a strong family history of breast cancer should be monitored carefully.
Consider ectopic pregnancy if a woman using Depo-Provera CI becomes pregnant or complains of severe abdominal pain.
Provide emergency medical treatment in case a patient develops Anaphylaxis and Anaphylactoid Reaction.
Depo-Provera CI should be discontinued if jaundice or disturbances of liver function develop.
There have been a few reported cases of convulsions in patients who were treated with Depo-Provera CI.
Diabetic patients should be monitored carefully for Carbohydrate Metabolism as a decrease in glucose tolerance has been observed in some patients .


Depo-Provera Contraceptive Injection - Dosage

The recommended dose is 150 mg of Depo-Provera Contraceptive Injection every 3 months (13 weeks) administered by deep Intramuscular injection in the gluteal or deltoid muscle.


Side Effects Of Depo-Provera Contraceptive Injection (Medroxyprogesterone Acetate)

The most common side effects of Depo-Provera Contraceptive Injection are menstrual irregularities (bleeding or spotting), abdominal pain/discomfort, weight gain, dizziness, headache, nervousness and decreased libido.


Further Information

Prescribing Information