Virovir Tablets | Generic Famvir | Famciclovir | Dosage | Uses | Side effects

Virovir Tablets (Generic Famvir) - Active Ingredient And Chemical structure

The active ingredient contained in Virovir Tablets is Famciclovir. Famciclovir is a white to pale yellow solid. It is freely soluble in acetone and methanol, and sparingly soluble in ethanol and isopropanol. The structure is shown below

Generic Forms and Brand names of Famvir

Virovir Tablets manufactured by FDC Ltd. , India is an effective treatment for Herpes labialis (cold sores), Genital herpes and Herpes zoster (shingles) in adult patients. Famvir which has the active ingredient Famciclovir is also sold under various other brand names.

Virovir Tablets - Preparations

Virovir is available as tablets of 250 mg .

Virovir Tablets - Storage Requirements

Virovir Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Generic Famvir (Famciclovir) - Uses

Generic Famvir in the form of Virovir Tablets is used to treat Herpes labialis (cold sores) Genital herpes and Herpes zoster (shingles) in adult patients.

Warnings and Precautions when using Virovir Tablets (Generic Famvir)

Acute renal failure cases have been reported in patients with underlying renal disease who have received inappropriately high doses of Virovir for their level of renal function. Dosage reduction is recommended when administering Virovir to patients with renal impairment.

Virovir Tablets (Generic Famvir) - Contraindications

Virovir Tablets is contraindicated in patients with known hypersensitivity to Famciclovir, its inactive components, or Denavir.

Virovir Tablets (Generic Famvir) - Dosage

Below are the recommended Dosage recommendation in Immunocompetent Adult Patients
Herpes labialis (cold sores):
The recommended dosage of FAMVIR for the treatment of recurrent herpes labialis is 1500 mg as a single dose. Therapy should be initiated at the first sign or symptom of herpes labialis (e.g., tingling, itching, burning, pain, or lesion).
Genital herpes:
Recurrent episodes: The recommended dosage of FAMVIR for the treatment of recurrent episodes of genital herpes is 1000 mg twice daily for 1 day. Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion).
Suppressive therapy: The recommended dosage of FAMVIR for chronic suppressive therapy of recurrent episodes of genital herpes is 250 mg twice daily.
Herpes zoster (shingles):
The recommended dosage of FAMVIR for the treatment of herpes zoster is 500 mg every 8 hours for 7 days. Therapy should be initiated as soon as herpes zoster is diagnosed.

Side Effects Of Virovir Tablets (Famciclovir)

The most common side effects of Virovir Tablets (Famciclovir) are headache and nausea. Less common side effects that may occur are Paresthesia, Migraine, Diarrhea, Vomiting, Flatulence, Abdominal Pain, Fatigue, Pruritus, Rash and Dysmenorrhea.

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Prescribing Information

Zovirax Tablets | Acyclovir | Dosage | Uses | Side effects

Zovirax Tablets (Acyclovir) - Active Ingredient And Chemical structure

The active ingredient contained in Zovirax Tablets is Acyclovir . Acyclovir is a white, crystalline powder with a molecular weight of 225. The maximum solubility in water at 37 °C is 2.5 mg/mL.The structure is shown below

Generic Forms and Brand names of Zovirax

Zovirax manufactured by GlaxoSmithKline (GSK), India is an effective treatment for chickenpox (varicella) or shingles (herpes zoster) and treating or suppressing genital herpes infections. Zovirax which has the active ingredient Acyclovir is also sold as Cyclovir, Herpex, Acivirax, Zovir, Acyclovir, Aciclovir, Zelitrex, Valtrex, Acyclovir and under various other brand names.

Zovirax Tablets (Acyclovir) - Uses

Acyclovir in the form of Zovirax Tablets is used to treat Herpes Zoster Infections (shingles), for the treatment of initial episodes and the management of recurrent episodes of genital herpes, treatment of chickenpox (varicella).

Zovirax Tablets - Contraindications

Zovirax is contraindicated in patients that have a hypersensitivity to acyclovir or valacyclovir. Dosage adjustment is recommended when administering Zovirax tablets to patients with renal impairment.
Caution should also be exercised when administering Zovirax to patients receiving potentially nephrotoxic agents since this may increase the risk of renal dysfunction and/or the risk of reversible central nervous system symptoms

Zovirax Tablets - Preparations

Zovirax Tablets is available as tablets of 200 mg, 400 mg and 800 mg. Each 200 mg tablet of Zovirax contains 200 mg of acyclovir and the inactive ingredients magnesium stearate, microcrystalline cellulose, povidone, and sodium starch glycolate.

Zovirax Tablets - Storage Requirements

Zovirax Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Zovirax Tablets - Symptoms Of Overdosage

The Adverse effects due to that have been reported in association with overdosage due to ingestion of up to 100 capsules (20 g)include agitation, coma, seizures, and lethargy. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored.

Zovirax Tablets - Dosage

Acute Treatment of Herpes Zoster:
800 mg every 4 hours orally, 5 times daily for 7 to 10 days.
Genital Herpes:
Treatment of Initial Genital Herpes:
200 mg every 4 hours, 5 times daily for 10 days.
Chronic Suppressive Therapy for Recurrent Disease:
400 mg 2 times daily for up to 12 months, followed by re-evaluation. Alternative regimens have included doses ranging from 200 mg 3 times daily to 200 mg 5 times daily. The frequency and severity of episodes of untreated genital herpes may change over time. After 1 year of therapy, the frequency and severity of the patient’s genital herpes infection should be reevaluated to assess the need for continuation of therapy with Zovirax.
Intermittent Therapy:
200 mg every 4 hours, 5 times daily for 5 days. Therapy should be initiated at the earliest sign or symptom (prodrome) of recurrence.
Treatment of Chickenpox:
Children (2 years of age and older):
20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. Children over 40 kg should receive the adult dose for chickenpox.
Adults and Children over 40 kg:
800 mg 4 times daily for 5 days. Intravenous Zovirax is indicated for the treatment of varicella-zoster infections in immunocompromised patients. When therapy is indicated, it should be initiated at the earliest sign or symptom of chickenpox.

Side Effects Of Zovirax Tablets

The most common side effects of Zovirax Tablets are were nausea,vomiting, diarrhea, headache and malaise.

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Azee Tablets | Generic Zithromax | Azithromycin | Dosage | Uses | Side effects

Azee Tablets (Generic Zithromax) - Active Ingredient And Chemical structure

The active ingredient contained in Azee is Azithromycin an azalide, a subclass of macrolide antibiotics, for oral administration. The structure is shown below

Generic Zithromax (Azithromycin) - Uses

Generic Zithromax in the form of Azee Tablets is used to treat Upper respiratory tract infections (including ear, nose and throat infections), Lower respiratory tract infections, Genitourinary tract infections (including sexually transmitted diseases), Skin and skin structure infections, Prophylaxis and treatment of malaria, Treatment of acne, Treatment of chlamydial conjunctivitis.

Azee Tablets (Generic Zithromax) - Preparations

Azee is available as tablets of 250 mg, 500 mg and 1000 mg. Each tablet contains Azithromycin Dihydrate equivalent to Azithromycin (anhydrous) USP 250 mg, 500 mg and 1000 mg respectively.

Generic Forms and Brand names of Zithromax (Azithromycin)

Azee manufactured by Cipla Ltd., India is used to treat or prevent bacterial infections like upper and lower genitourinary tract infections, respiratory tract infections(including ear, nose and throat infections), skin and skin structure infections. Zithromax which has the active ingredient Azithromycin is also sold as Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax and under various other brand names.

Azee Tablets (Generic Zithromax) - Storage Requirements

Azee Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Azee Tablets (Generic Zithromax) - Dosage

Below is given the recommended adult dosage to treat various indications:
Mild to moderate lower respiratory tract infections, upper respiratory tract infections and uncomplicated skin and soft tissue infections:
Adults Dosage:500 mg as a single dose on the first day followed by 250 mg once daily on days 2 to 5 for a total dose of 1.5 g or 500 mg once daily for 3 days.
Sexually transmitted diseases:
– Gonorrhoea: 2 gm as a stat dose
– Chancroid: 1 gm as a stat dose
– Non-gonococcal urethritis and cervicitis due to C. trachomatis –1 gm as a stat dose
– Syphilis: 1 gm o.d. for 5 days or 500 mg o.d. for 10 days.
Malaria:
– Prophylaxis: 500 mg on first day followed by 250 mg/day for 7 days.
– Treatment: 1000-1500 mg once daily for 3 days with usual doses of chloroquine.
Acne:
250-500 mg on 3 consecutive days in a week for 12 weeks.

Azee Tablets - Contraindications

Azee is contraindicated in patients which are allergic to azithromycin, erythromycin, or any other macrolide or ketolide antibiotics.

Side Effects Of Azee Tablets (Generic Zithromax)

The most common side effects of Azee tablets are nausea, vomiting, diarrhea, or abdominal pain. Rarely occuring side effects are Palpitations, chest pain, Dyspepsia, flatulence, vomiting, melena and cholestatic jaundice, Monilia, vaginitis and nephritis, Dizziness, headache, vertigo and somnolence, Fatigue, Rash, pruritus, photosensitivity and angioedema.

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Prescribing Information