Predmet Tablets (Generic Medrol) - Active Ingredient And Chemical structure
The active ingredient contained in Predmet Tablets is Methylprednisolone which is a glucocorticoid. Methylprednisolone is a white, odourless, crystalline powder that is insoluble in water, sparingly soluble in alcohol, slightly soluble in acetone, and in chloroform, and very slightly soluble in ether. The structure is shown below
Generic Forms and Brand names of Medrol
Predmet Tablets manufactured by Sun Pharmaceutical Industries Ltd, India is an effective treatment for inflammatory effects in disorders of different parts of the body. Medrol which has the active ingredient Methylprednisolone Sodium Succinate is also sold as Solu-Medrol, Melpred and under various other brand names.
Predmet Tablets - Preparations
Predmet is available as tablets of 4 mg, 8 mg and 16 mg tablets. Each Medrol tablet contains 4 mg 8 mg or 16 mg of methylprednisolone.
Predmet Tablets - Storage Requirements
Predmet Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.
Generic Medrol (Methylprednisolone Sodium Succinate) - Uses
Generic Medrol in the form of Predmet Tablets is primarily used to treat inflammatory conditions in various organ systems of the body. It is also used for varrious other indications as detailed below:
Endocrine Disorders: Primary or secondary adrenocortical insufficiency, Congenital adrenal hyperplasia. Nonsuppurative thyroiditis. Hypercalcemia associated with cancer.
Rheumatic Disorders: As adjunctive therapy for short-term administration in: psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis, ankylosing spondylitis;acute and subacute bursitis; acute non specific tenosynovitis; acute gouty arthritis; post-traumatic osteoarthritis; synovitis of osteoarthritis; epicondylitis.
Collagen Diseases: During an exacerbation or as maintenance therapy in selected cases of: systemic lupus erythematosus; systemic dermatomyositis (polymyositis); acute rheumatic carditis; polymyalgia rheumatica; giant cell arteritis.
Dermatologic Diseases: pemphigus; bullous dermatitis herpetiformis; severe erythema multiforme (Stevens-Johnson syndrome); exfoliative dermatitis; mycosis fungoides; severe psoriasis; severe seborrheic dermatitis.
Allergic State: Control of severe of incapacitating allergic conditions intractable to adequate trials of conventional treatment.
Ophthalmic Diseases: Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa.
Respiratory Diseases: symptomatic sarcoidosis; Loeffler’s syndrome not manageable by other means; berylliosis; fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy; aspiration pneumonitis.
Hematologic Disorders: idiopathic thrombocytopenic purpura in adults; secondary thrombocytopenia in adults; acquired (autoimmune) hemolytic anemia; erythroblastopenia (RBC anemia); congenital (erythroid) hypoplastic anemia.
Neoplastic Disorders: For palliative management of: leukemias and lymphomas in adults; acute leukemia of childhood.
Edematous States: To induce a diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus.
Gastrointestinal Diseases: To tide the patient over a critical period of the disease in: ulcerative colitis; regional enteritis.
Nervous System: acute exacerbations of multiple sclerosis; management of edema associated with brain tumour.
Miscellaneous: Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy. Trichinosis with neurologic or myocardial involvement.
Predmet Tablets - Dosage
The initial recommended dosage of Predmet Tablets (methylprednisolone) may vary from 4 to 48 mg per day depending on the specific indication being treated.
Predmet Tablets - Contraindications
Predmet (methylprednisolone) Tablets are contraindicated in patients that have Systemic fungal infections. It is also contraindicated in persons that have a known hypersensitivity to methylprednisolone or any other component of the tablets.
Side Effects Of Predmet Tablets ( Methylprednisolone)
The side effects of Methylprednisolone tablets are given below:
Fluid and Electrolyte Disturbances: