Calutide Tablets | Generic Casodex | Dosage | Uses | Side effects

Calutide Tablets (Generic Casodex) - Active Ingredient And Chemical structure

The active ingredient contained in Calutide Tablets is bicalutamide. Bicalutamide is a fine white to off white powder which is practically insoluble in water but soluble in acetone and tetrahydrofuran. The structure is shown below

Generic Forms and Brand names of Casodex Tablets (Bicalutamide)

Calutide Tablets manufactured by Cipla Ltd., India is an effective treatment for advanced prostate cancer in combination therapy with a luteinizing hormone-releasing hormone (LHRH) analog therapy. Generic Casodex which has the active ingredient Bicalutamide is also sold under various other brand names.

Calutide Tablets - Preparations

Calutide Tablets is available as tablets of 50 mg. Each film-coated tablet contains 50 mg of Bicalutamide.

Calutide Tablets - Storage Requirements

Calutide Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Calutide Tablets (Generic Casodex) - Uses

Generic Casodex in the form of Calutide Tablets is used for the treatment of advanced prostate cancer (D2 metastatic prostate cancer) in combination with LHRH analogue therapy.

Calutide Tablets - Dosage

The recommended dose for Calutide therapy in combination with an LHRH (luteinizing hormone-releasing hormone) analog is one 50 mg tablet once daily (either in the morning or evening), with or without food. It is recommended that Calutide be taken at the same time each day. Treatment with Calutide has to be started at the same time as the treatment with an LHRH analog.

Calutide Tablets - Contraindications

Calutide Tablets is contraindicated in any patient who has shown a hypersensitivity reaction to the medication or any of the tablet's components. It is also is contraindicated in women.

Side Effects Of Calutide Tablets (Generic Casodex)

The most common side effects of Calutide Tablets in combination with a LHRH-A are hot flashes, pain (including general, back, pelvic and abdominal), asthenia, constipation, infection, nausea, peripheral edema, dyspnea, diarrhea, hematuria, nocturia and anemia.

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Antiflu Capsules | Generic Tamiflu | Dosage | Uses | Side effects

Antiflu Capsules (Generic Tamiflu)- Active Ingredient And Chemical structure

The active ingredient contained in Antiflu Capsules is Oseltamivir Phosphate. Oseltamivir phosphate is a white crystalline solid. The structure is shown below

Generic Forms and Brand names of Tamiflu Capsules (Oseltamivir Phosphate)

Antiflu Capsules manufactured by Cipla Ltd, India has been used effectively to treat and prevent influenza A virus and influenza B virus infection. Generic Tamiflu Capsules which has the active ingredient Oseltamivir Phosphate is also sold under various other brand names.

Antiflu Capsules Preparations

Antiflu is available as capsules of 75 mg. Each capsule contains Oseltamivir phosphate equivalent to 75 mg of Oseltamivir.

Antiflu Capsules - Storage Requirements

Antiflu Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep out of reach of children and pets.

Uses of Antiflu Capsules (Generic Tamiflu)

Generic Tamiflu in the form of Antiflu Capsules is used to treat influenza viruses types A and B and against Swine Influenza Virus (SIV - SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H3N1, H3N2, and H2N3).

Antiflu Capsules Dosage

Standard Dosage – Treatment of Influenza

Adults and Adolescents
The recommended oral dose of Antiflu for treatment of influenza in adults and adolescents 13 years and older is 75 mg twice daily for 5 days. Treatment should begin within 2 days of onset of symptoms of influenza.
Pediatric Patients
Antiflu is not indicated for treatment of influenza in pediatric patients younger than 1 year. The recommended oral dose of Antiflu for pediatric patients 1 year and older is shown in Table 1 below.Antiflu oral suspension may also be used by patients who cannot swallow a capsule.

Table 1: Oral Dose of Antiflu for Treatment of Influenza in Pediatric Patients by Weight

Body Weight(kg)	Body Weight(lbs)	Recommended Dose for 5 Days
≤15 kg	≤ 33 lbs	30 mg twice daily
>15 kg to 23 kg	>33 lbs to 51 lbs	45 mg twice daily
>23 kg to 40 kg	>51 lbs to 88 lbs	60 mg twice daily
>40 kg	>88 lbs	75 mg twice daily

Standard Dosage – Prophylaxis of Influenza

Adults and Adolescents
The recommended oral dose of Antiflu for prophylaxis of influenza in adults and adolescents 13 years and older following close contact with an infected individual is 75 mg once daily for at least 10 days. Therapy should begin within 2 days of exposure. The recommended dose for prophylaxis during a community outbreak of influenza is 75 mg once daily. Safety and efficacy have been demonstrated for up to 6 weeks in immunocompetent patients. Safety has been demonstrated for up to 12 weeks in immunocompromised patients.The duration of protection lasts for as long as dosing is continued.
Pediatric Patients
The safety and efficacy of Antiflu for prophylaxis of influenza in pediatric patients younger than 1 year of age have not been established. The recommended oral dose of Antiflu for pediatric patients 1 year and older following close contact with an infected individual is shown in Table 2. Antiflu for oral suspension may also be used by patients who cannot swallow a capsule.

Table 2:Oral Dose of Antiflu for Prophylaxis of Influenza in Pediatric Patients by Weight

Body Weight(kg)	Body Weight(lbs)	Recommended Dose for 10 Days
≤15 kg	≤ 33 lbs	30 mg once daily
>15 kg to 23 kg	>33 lbs to 51 lbs	45 mg once daily
>23 kg to 40 kg	>51 lbs to 88 lbs	60 mg once daily
>40 kg	>88 lbs	75 mg once daily

Side Effects Of Antiflu Capsules

The most common side effects of Antiflu therapy are nausea, vomiting, diarrhea, abdominal pain, and headache. Rare ADRs include: hepatitis and elevated liver enzymes, rash, allergic reactions including anaphylaxis, and Stevens-Johnson syndrome. Less common and rarely occuring side effects that may occur are anaphylaxis and serious skin reactions including toxic epidermal necrolysis, Stevens-Johnson Syndrome,erythema multiforme, toxic epidermal necrolysis, cardiac arrhythmia, seizure, confusion, aggravation of diabetes, and haemorrhagic colitis.

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Megalis Tablets | Generic Cialis | Dosage | Uses | Side effects

Megalis Tablets (Generic Cialis)- Active Ingredient And Chemical structure

The active ingredient contained in Megalis Tablets is Tadalafil . The structure is shown below

Generic Forms and Brand names of Tadalafil Tablets

Megalis Tablets manufactured by Macleods Pharmaceuticals, India is an effective treatment for erectile dysfunction. Generic Cialis which has the active ingredient Tadalafil is also sold as Tadacip manufactured by Cipla Ltd, India and under various other brand names.

Megalis Tablets - Preparations

Megalis Tablets is available as tablets of 10 mg and 20 mg .

Megalis Tablets - Storage Requirements

Megalis Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Store this medicine out of the reach of children and pets.

Megalis Tablets - Uses

Generic Cialis in the form of Megalis Tablets is used for the treatment of erectile dysfunction.

Megalis Tablets - Dosage

The recommended starting dose of Megalis Tablets (Generic Cialis) is is 10 mg, taken prior to anticipated sexual activity. It is to be used as and when required with or without food. The dose may be increased to 20 mg based on individual efficacy and tolerability. The maximum dosing frequency is once per day.

Megalis Tablets - Contraindications

Using Megalis Tablets to treat patients who are using any form of organic nitrate, either regularly and/or intermittently, is contraindicated. Generic Cialis (Megalis) is also contraindicated in patients with hypersensitivity to tadalafil. Treatments for erectile dysfunction, including Megalis, should not be used in men for whom sexual activity is not advisable because of their cardiovascular status.

Precautions And Warnings When Using Megalis Tablets

Patients should seek emergency treatment if an erection lasts for more than 4 hours. Megalis Tablets have to be used with caution in patients predisposed to priapism.

Side Effects Of Megalis Tablets

The most common side effects of Megalis Tablets are Headache, Dyspepsia, Back pain, Myalgia, Nasal congestion , Flushing and Pain in limb.

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