Thursday, July 7, 2011

Calutide Tablets | Generic Casodex | Dosage | Uses | Side effects

Calutide Tablets (Generic Casodex) - Active Ingredient And Chemical structure

The active ingredient contained in Calutide Tablets is bicalutamide. Bicalutamide is a fine white to off white powder which is practically insoluble in water but soluble in acetone and tetrahydrofuran. The structure is shown below

Structure Of Bicalutamide


Generic Forms and Brand names of Casodex Tablets (Bicalutamide)

Calutide Tablets manufactured by Cipla Ltd., India is an effective treatment for advanced prostate cancer in combination therapy with a luteinizing hormone-releasing hormone (LHRH) analog therapy. Generic Casodex which has the active ingredient Bicalutamide is also sold under various other brand names.


Calutide Tablets - Preparations

Calutide Tablets is available as tablets of 50 mg. Each film-coated tablet contains 50 mg of Bicalutamide.


Calutide Tablets - Storage Requirements

Calutide Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Calutide Tablets (Generic Casodex) - Uses

Generic Casodex in the form of Calutide Tablets is used for the treatment of advanced prostate cancer (D2 metastatic prostate cancer) in combination with LHRH analogue therapy.


Calutide Tablets - Dosage

The recommended dose for Calutide therapy in combination with an LHRH (luteinizing hormone-releasing hormone) analog is one 50 mg tablet once daily (either in the morning or evening), with or without food. It is recommended that Calutide be taken at the same time each day. Treatment with Calutide has to be started at the same time as the treatment with an LHRH analog.


Calutide Tablets - Contraindications

Calutide Tablets is contraindicated in any patient who has shown a hypersensitivity reaction to the medication or any of the tablet's components. It is also is contraindicated in women.


Side Effects Of Calutide Tablets (Generic Casodex)

The most common side effects of Calutide Tablets in combination with a LHRH-A are hot flashes, pain (including general, back, pelvic and abdominal), asthenia, constipation, infection, nausea, peripheral edema, dyspnea, diarrhea, hematuria, nocturia and anemia.


Further Information

Prescribing Information