Sirdalud Tablets | Generic Zanaflex | Dosage | Uses | Side effects

Sirdalud Tablets (Generic Zanaflex) - Active Ingredient And Chemical structure

The active ingredient contained in Sirdalud Tablets (Generic Zanaflex) is Tizanidine Hydrochloride. Tizanidine HCl (tizanidine) is a white to off-white, fine crystalline powder, which is 15 odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol. The structure is shown below

Generic Forms and Brand names of Zanaflex (Tizanidine HCl)

Sirdalud Tablets manufactured by Novartis is used to help relax certain muscles in your body caused by medical problems. Zanaflex which has the active ingredient Tizanidine Hydrochloride is also sold under various other brand names.

Sirdalud Tablets - Preparations

Sirdalud tablets are available as 2 mg and 4 mg tablets for oral administration. Sirdalud tablets are composed of the active ingredient, tizanidine hydrochloride 29 (2.29 mg equivalent to 2 mg tizanidine base and 4.58 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, silicon dioxide colloidal, stearic acid microcrystalline cellulose and anhydrous lactose.

Sirdalud Tablets - Storage Requirements

Sirdalud Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Sirdalud Tablets - Uses

Tizanidine Hydrochloride in the form of Sirdalud Tablets is used to relax certain muscles in your body caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.

Sirdalud Tablets - Contraindications

Concomitant use of Sirdalud Tablets (tizanidine) with fluvoxamine or with ciprofloxacin, is contraindicated. This pharmacokinetic interaction can result in potentially serious adverse events. Sirdalud is also contraindicated in patients with known hypersensitivity to Tizanidine or other inactive ingredients.

Sirdalud Tablets - Dosage

The recommended starting dose of Sirdalud is a single oral dose of 4 mg due to dose related nature of tizanidine’s common adverse effects. The dose has to be gradually increased in 2 to 4 mg steps to optimum effect i.e. To obtain satisfactory reduction of muscle tone at a tolerated dose. Please consult your doctor for exact dosing instructions.

Side Effects Of Sirdalud Tablets

The most common side effects of Sirdalud Tablets are asthenia (weakness, fatigue and/or tiredness) , somnolence , dry mouth , increased spasm or tone , and dizziness . Less common side effects that may occur are were Infection Constipation Liver function tests abnormal, Vomiting, Speech disorder, Amblyopia (blurred vision), Urinary frequency, Flu symptom, SGPT/ALT increased, Dyskinesia ,Nervousness, Pharyngitis and Rhinitis

Further Information

Prescribing Information

Buspin Tablets | Generic Buspar | Dosage | Uses | Side effects

Buspin Tablets (Generic Buspar) - Active Ingredient And Chemical structure

The active ingredient contained in Buspin Tablets (Generic Buspar) is Buspirone HCl. Buspirone Hydrochloride is a white crystalline compound that is soluble in water. The structure is shown below

Generic Forms and Brand names of Buspar Tablets (Buspirone Hydrochloride)

Buspin Tablets manufactured by Intas Pharmaceuticals Ltd., India is an effective treatment for Generalized Anxiety Disorder (GAD) of very mild to moderate intensity, without any panic attacks. Buspar which has the active ingredient Buspirone Hydrochloride is also sold as Dividose and under various other brand names.

Buspin Tablets (Generic Buspar) - Uses

Generic Buspar Tablets in the form of Buspin Tablets is used for the management of anxiety disorders or for the short term relief of the symptoms of anxiety.

Buspin Tablets (Generic Buspar) - Preparations

Buspin is available as tablets of 5 mg, 10 mg, 15 mg, or 30 mg for oral administration. These tablets contains 5 mg, 10 mg, 15 mg or 30 mg of buspirone hydrochloride.

Buspin Tablets (Generic Buspar) - Storage Requirements

Buspin Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from Children and pets.

Buspin Tablets (Generic Buspar) - Dosage

The recommended initial dose is 15 mg daily (7.5 mg two times a day). Inorder to achieve an optimal therapeutic response, the dosage may be increased 5 mg per day, as needed at intervals of 2 to 3 days. The maximum daily dosage of Buspin should not exceed 60 mg per day.

Buspin Tablets (Generic Buspar) - Contraindications And Warnings

Buspin is contraindicated in patients hypersensitive to buspirone hydrochloride or to any inactive ingredient. Administration of Buspin tablets to a patient taking a monoamine oxidase inhibitor (MAOI) may pose a hazard. Occurrences of high blood pressure when Buspin (buspirone hydrochloride) has been added to a regimen including an MAOI have been reported.

Side Effects Of Buspin Tablets (Generic Buspar)

The most common side effects of Buspin Tablets include dizziness, nausea, headache, nervousness, lightheadedness, and excitement. Rarely occuring side effects that were reported post marketing include allergic reactions (including urticaria), angioedema, cogwheel rigidity, dizziness (rarely reported as vertigo), dystonic reactions (including dystonia), ataxias, extrapyramidal symptoms, dyskinesias (acute and tardive), ecchymosis, emotional lability, serotonin syndrome, transient difficulty with recall, urinary retention, visual changes (including tunnel vision), parkinsonism, akathisia, restless leg syndrome, and restlessness.

Further Information

Prescribing Information

Tryptomer Tablets | Generic Elavil | Dosage | Uses | Tryptomer Side effects

Tryptomer Tablets (Generic Elavil) - Active Ingredient And Chemical structure

The active ingredient contained in Tryptomer Tablets (Generic Elavil) is Amitriptyline Hydrochloride. Amitriptyline HCl is a white, odorless, crystalline compound that is freely soluble in water. The structure is shown below

Generic Elavil (Amitriptyline Hydrochloride) - Uses

Amitriptyline Hydrochloride in the form of Generic Elavil Tablets (Tryptomer Tablets) is used to treat depresssion. Generic Elavil is also used aa a sedative, and is useful in depressed patients with insomnia, restlessness, and nervousness.

Generic Forms and Brand names of Elavil Tablets

Tryptomer manufactured by Wockhardt Ltd., India is an effective treatment for depression . It is also used to relive the symptoms of migraines, tension headaches, anxiety attacks and some schizophrenic symptoms. Elavil which has the active ingredient Amitriptyline Hydrochloride is also sold as Tryptizol, Laroxyl, Sarotex, Lentizol and under various other brand names.

Tryptomer Tablets Preparations

Tryptomer Tablets (Generic Elavil) are available as tablets of 10 mg, 25 mg and 75 mg.

Tryptomer Tablets - Storage Requirements

Tryptomer Tablets (Generic Elavil) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Tryptomer Tablets (Generic Elavil) - Dosage

The adult dosage for Tryptomer Tablets is 25 mg three times a day. The dosage may be increased if necessary to a total of 150 mg a day. In the case of adolescent and elderly Patients lower dosages are recommended. 10 mg three times a day or 10 mg twice with 20 mg at bedtime is recommended. Dosage should be started at a low level and increased gradually, after carefully observing the clinical response of the patient to Tryptomer and any evidence of intolerance.

Tryptomer Tablets (Generic Elavil) - Contraindications And Warnings

Tryptomer is contraindicated in patients who have shown prior hypersensitivity to the active ingredient Amitriptyline HCl or to any inactive ingredient.Tryptomer Tablets should not be given along with or within at least 14 days following the discontinuance of a monoamine oxidase inhibitor (MOI). Generic Elavil should not be used during the acute recovery phase following myocardial infarction, and in the presence of acute congestive heart failure.
Tryptomer may block the antihypertensive action of guanethidine or similarly acting compounds. Generic Elavil should be used with caution in patients with a history of seizures and, because of its atropine like action, in patients with a history of urinary retention, angle-closure glaucoma or increased intraocular pressure. In patients with angle-closure glaucoma, even average doses of Generic Elavil may precipitate an attack. Patients with cardiovascular disorders have to be observed closely.

Withdrawal Symptoms

Abrupt cessation of treatment after prolonged administration of Tryptomer Tablets may give rise to nausea, headache, and malaise. Gradual dosage reduction has been reported to produce, within two weeks, transient symptoms including irritability, restlessness, and dream and sleep disturbance.

Side Effects Of Tryptomer Tablets (Generic Elavil)

The most common side effects of Tryptomer Tablets are described below:
Cardiovascular:
Myocardial infarction; stroke; nonspecific EGG changes and changes in AV conduction; heart block; arrhythmias; hypotension, particularly orthostatic hypotension; syncope; hypertension; tachycardia; palpitation.
CNS and Neuromuscular:
Coma; seizures; hallucinations; delusions; confusional states;disorientation; incoordination; ataxia; tremors; peripheral neuropathy; numbness, tingling. and paresthesias of the extremities; extrapyramidal symptoms including abnormal involuntary movements and tardive dyskinesia; dysarthria; disturbed concentration; excitement; anxiety; insomnia; restlessness; nightmares; drowsiness; dizziness; weakness; fatigue; headache; syndrome of inappropriate ADH (antidiuretic hormone) secretion; tinnitus; alteration in EEG patterns.
Anticholinergic:
Paralytic ileus; hyperpyrexia; urinary retention; dilatation of the urinary tract; constipation; blurred vision, disturbance of accommodation, increased ocular pressure, mydriasis; dry mouth.
Allergic:
Skin rash; urticaria; photosensitization; edema of face and tongue.
Hematologic:
Bone marrow depression including agranulocytosis, leukopenia, thrombocytopenia; purpura; eosinophilia.
Gastrointestinal:
Rarely hepatitis (including altered liver function and jaundice); nausea; epigastric distress; vomiting; anorexia; stomatitis' peculiar taste; diarrhea; parotid swelling; black tongue
Endocrine:
Testicular swelling and gynecomastia in the male; breast enlargement and galactorrhea in the female; increased or decreased libido; impotence; elevation and lowering of blood sugar levels.
Other Adverse Reactions:
Alopecia; edema; weight gain or loss; urinary frequency; increased perspiration.