Sirdalud Tablets (Generic Zanaflex) - Active Ingredient And Chemical structure
The active ingredient contained in Sirdalud Tablets (Generic Zanaflex) is Tizanidine Hydrochloride. Tizanidine HCl (tizanidine) is a white to off-white, fine crystalline powder, which is 15 odorless or with a faint characteristic odor. Tizanidine is slightly soluble in water and methanol. The structure is shown below
Generic Forms and Brand names of Zanaflex (Tizanidine HCl)
Sirdalud Tablets manufactured by Novartis is used to help relax certain muscles in your body caused by medical problems. Zanaflex which has the active ingredient Tizanidine Hydrochloride is also sold under various other brand names.
Sirdalud Tablets - Preparations
Sirdalud tablets are available as 2 mg and 4 mg tablets for oral administration. Sirdalud tablets are composed of the active ingredient, tizanidine hydrochloride 29 (2.29 mg equivalent to 2 mg tizanidine base and 4.58 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, silicon dioxide colloidal, stearic acid microcrystalline cellulose and anhydrous lactose.
Sirdalud Tablets - Storage Requirements
Sirdalud Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.
Sirdalud Tablets - Uses
Tizanidine Hydrochloride in the form of Sirdalud Tablets is used to relax certain muscles in your body caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.
Sirdalud Tablets - Contraindications
Concomitant use of Sirdalud Tablets (tizanidine) with fluvoxamine or with ciprofloxacin, is contraindicated. This pharmacokinetic interaction can result in potentially serious adverse events. Sirdalud is also contraindicated in patients with known hypersensitivity to Tizanidine or other inactive ingredients.
Sirdalud Tablets - Dosage
The recommended starting dose of Sirdalud is a single oral dose of 4 mg due to dose related nature of tizanidine’s common adverse effects. The dose has to be gradually increased in 2 to 4 mg steps to optimum effect i.e. To obtain satisfactory reduction of muscle tone at a tolerated dose. Please consult your doctor for exact dosing instructions.
Side Effects Of Sirdalud Tablets
The most common side effects of Sirdalud Tablets are asthenia (weakness, fatigue and/or tiredness) , somnolence , dry mouth , increased spasm or tone , and dizziness . Less common side effects that may occur are were Infection Constipation Liver function tests abnormal, Vomiting, Speech disorder, Amblyopia (blurred vision), Urinary frequency, Flu symptom, SGPT/ALT increased, Dyskinesia ,Nervousness, Pharyngitis and Rhinitis
