Crestor Tablets | Rosuvastatin Calcium | Dosage | Uses | Side effects

Crestor Tablets (Rosuvastatin Calcium) - Active Ingredient And Chemical structure

Crestor (Rosuvastatin Calcium) is a synthetic lipid-lowering agent for oral administration. The active ingredient contained in Crestor is Rosuvastatin Calcium. Rosuvastatin calcium is a white amorphous powder that is sparingly soluble in water and methanol, and slightly soluble in ethanol. The structure is shown below

Generic Forms and Brand names of Crestor Tablets (Rosuvastatin Calcium)

Crestor Tablets manufactured by Astra Zeneca, India is an effective treatment to slow down the production of cholesterol in the body and to prevent cardiovascular disease.

Crestor Tablets (Rosuvastatin Calcium) - Preparations

Crestor is available as tablets of 5 mg, 10 mg and 20 mg.

Crestor Tablets (Rosuvastatin Calcium) - Storage Requirements

Crestor Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Crestor Tablets (Rosuvastatin Calcium) - Uses

Rosuvastatin Calcium in the form of Crestor Tablets is used to treat the below mentioned indications:
Hyperlipidemia and Mixed Dyslipidemia
Crestor is indicated as adjunctive therapy to diet to reduce elevated Total-C, LDL-C, ApoB, nonHDL-C, and triglycerides and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.
Hypertriglyceridemia
Crestor is indicated as adjunctive therapy to diet for the treatment of adult patients with hypertriglyceridemia
Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia)
Crestor is indicated as an adjunct to diet for the treatment of patients with primary dysbetalipoproteinemia (Type III Hyperlipoproteinemia).
Homozygous Familial Hypercholesterolemia
Crestor is indicated as adjunctive therapy to other lipid-lowering treatments (e.g., LDL apheresis) or alone if such treatments are unavailable to reduce LDL-C, Total-C, and ApoB in adult patients with homozygous familial hypercholesterolemia.
Slowing of the Progression of Atherosclerosis
Crestor is indicated as adjunctive therapy to diet to slow the progression of atherosclerosis in adult patients as part of a treatment strategy to lower Total-C and LDL-C to target levels.

Crestor Tablets (Rosuvastatin Calcium) - Dosage

The recommended dose range for Crestor is 5 to 40 mg orally once daily. Crestor can be administered as a single dose at any time of day, with or without food.
Hyperlipidemia, Mixed Dyslipidemia, Hypertriglyceridemia, Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia) and Slowing of the Progression of Atherosclerosis
The recommended starting dose of Crestor is 10 mg once daily. For patients with marked hyperlipidemia (LDL-C > 190 mg/dL) and aggressive lipid targets, a 20 mg starting dose may be considered.
Homozygous Familial Hypercholesterolemia
The recommended starting dose of Crestor is 20 mg once daily.

Crestor Tablets (Rosuvastatin Calcium) - Contraindications

Crestor is contraindicated in patients with a known hypersensitivity to Rosuvastatin Calcium or any inactive component of this medication.

Side Effects Of Crestor Tablets (Rosuvastatin Calcium)

The most common side effects of are headache, myalgia, abdominal pain, asthenia and nausea. Serious side effects include Rhabdomyolysis with myoglobinuria, acute renal failure, myopathy and Liver enzyme abnormalities.

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Distinon Tablets | Generic Mestinon | Pyridostigmine Bromide | Dosage | Uses | Side effects

Distinon Tablets (Pyridostigmine Bromide) - Active Ingredient And Chemical structure

Distinon Tablets (Generic Mestinon) is an orally active cholinesterase inhibitor. The active ingredient contained in Distinon Tablets is Pyridostigmine Bromide. The structure is shown below

Generic Forms and Brand names of Mestinon (Pyridostigmine Bromide)

Distinon manufactured by Samarth Pharma Pvt. Ltd. , India is an effective treatment for myasthenia gravis. Mestinon which has the active ingredient Pyridostigmine Bromide is also sold as Regonol and under various other brand names.

Pyridostigmine Bromide (Generic Mestinon) - Uses

Pyridostigmine Bromide in the form of Generic Mestinon Tablets is used to treat muscle weakness in people with myasthenia gravis as well as counter the effects of curariform drug toxicity.

Distinon Tablets (Pyridostigmine Bromide) - Preparations

Distinon Tablets (Generic Mestinon) is available as tablets of 60 mg .

Distinon Tablets (Pyridostigmine Bromide) - Storage Requirements

Distinon Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Distinon Tablets (Generic Mestinon) - Dosage

The size and frequency of dosage of Distinonmust be adjusted to the needs of the individual patient. The average dose of Distinon is ten 60 mg tablets daily, spaced to provide maximum relief when maximum strength is needed.

Distinon (Generic Mestinon) Tablets (Pyridostigmine Bromide) - Contraindications

Distinon is contraindicated in patients with a hypersensitivity to Pyridostigmine Bromide or any inactive ingredient present in the medication. Mestinon is contraindicated in mechanical intestinal or urinary obstruction, and particular caution should be used in its administration to patients with bronchial asthma.

Side Effects Of Distinon Tablets (Generic Mestinon)

The most common Muscarinic side effects of Generic Mestinon are nausea, vomiting, diarrhea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, miosis and diaphoresis. Nicotinic side effects are comprised chiefly of muscle cramps, fasciculation and weakness.

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Nexpro Tablets | Generic Nexium | Esomeprazole | Dosage | Uses | Side effects

Nexpro Tablets (Generic Nexium) - Active Ingredient And Chemical structure

The active ingredient contained in Nexpro Tablets is Esomeprazole Magnesium, a compound that inhibits gastric acid secretion. Esomeprazole Magnesium is a white to slightly colored crystalline powder which is slightly soluble in water. The structure is shown below

Generic Nexium (Esomeprazole Magnesium) - Uses

Generic Nexium (Esomeprazole Magnesium) in the form of Nexpro Tablets is used in the treatment of Gastroesophageal Reflux Disease (GERD), Risk Reduction of NSAID-Associated Gastric Ulcer, H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence, Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome.

Generic Forms and Brand names of Nexium (Esomeprazole Magnesium)

Nexpro Tablets manufactured by Torrent Pharmaceuticals Ltd., India is an effective treatment for symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. Nexium which has the active ingredient Esomeprazole Magnesium is also sold as Sompraz, Esopral, Lucen, Axagon, Nexiam or Zoleri and under various other brand names.

Nexpro Tablets (Generic Nexium) - Preparations

Nexpro Tablets (Esomeprazole Magnesium) are available as tablets of 20 mg and 40 mg .

Nexpro Tablets - Storage Requirements

Nexpro Tablets (Esomeprazole Magnesium) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.

Nexpro Tablets (Esomeprazole Magnesium) - Dosage

The recommended dosage of Nexpro tablets for various indications is given below:

Indication	Dose	Frequency
Gastroesophageal Reflux Disease (GERD)
Healing of Erosive Esophagitis	20 mg or 40 mg	Once Daily for 4 to 8 Weeks
Maintenance of Healing of Erosive Esophagitis	20 mg	Once Daily
Symptomatic Gastroesophageal Reflux Disease	20 mg	Once Daily for 4 Weeks
Risk Reduction of NSAID Associated Gastric Ulcer	20 mg or 40 mg	Once Daily for up to 6 months
H.pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Triple Therapy:
Nexpro	40 mg	Once Daily for 10 Days
Amoxicillin	1000 mg	Twice Daily for 10 Days
Clarithromycin	500 mg	Twice Daily for 10 Days
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome	40 mg	Twice Daily

Nexpro Tablets (Generic Nexium) - Contraindications

Nexpro is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles.

Side Effects Of Nexpro Tablets (Generic Nexium)

The most common side effects of are Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth.

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