Wednesday, June 29, 2011

Finpecia Tablets | Finpecia Cipla | Dosage | Side effects

Finpecia Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Finpecia Tablets is Finasteride. Finasteride is a white crystalline powder with a melting point near 250°C. It is freely soluble in chloroform and in lower alcohol solvents but is practically insoluble in water. The structure is shown below
Structure Of Finasteride


Generic Forms and Brand names of Propecia

Finpecia manufactured by Cipla Ltd., India is an effective treatment for male pattern hair loss. Generic Propecia which has the active ingredient Finasteride is also sold as Finast, Propecia, Proscar, Finara, Finalo, Prosteride, Gefina, Appecia, Finax, Fincar and under various other brand names.


Finpecia - Preparations

Finpecia manufactured by Cipla is available as film-coated tablets that contain 1 mg of Finasteride for oral administration.


Finpecia Tablets - Storage Requirements

Finpecia Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Finpecia Tablets - Uses

Generic Propecia in the form of Finpecia Tablets is used to treat male pattern hair loss (androgenetic alopecia). Safety and efficacy were demonstrated in men between 18 to 41 years of age with mild to moderate hair loss of the vertex and anterior mid-scalp area.


Finpecia Tablets - Dosage

The recommended dosage of Cipla Finpecia is 1 mg tablet orally once a day. Finpecia may be administered with or without meals.Daily use for three months or more is necessary before benefit is observed. Continued use is recommended to sustain benefit (i.e. Hair growth and prevention of hair loss). Withdrawal of treatment leads to reversal of effect within 12 months.


Side Effects Of Finpecia Tablets

The most common side effects of Finpecia Tablets are Decreased Libido, Erectile Dysfunction, Ejaculation Disorder(Decreased Volume of Ejaculate), Impotence, hypersensitivity reactions, Breast Enlargement, Breast Tenderness, Rash, Pruritus, Urticaria, Swelling of the lips and face and Testicular pain.


Further Information

Prescribing Information

Tuesday, June 28, 2011

Nizral Cream | Generic Ketoconazole Cream | Uses | Dosage | Side Effects

Generic Nizoral Cream (Ketoconazole Cream) - Active Ingredient And Chemical structure

The active ingredient contained in Generic Ketoconazole Cream (Nizoral Cream) is Ketoconazole. The structure is shown below
Structure Of  Ketoconazole


Generic Forms and Brand names of Ketoconazole Cream

Nizral Cream manufactured by Johnson and Johnson, India is an effective topical treatment of tinea corporis, tinea cruris and tinea pedis caused by Trichophyton rubrum, T. mentagrophytes and Epidermophyton floccosum; in the treatment of tinea (pityriasis) versicolor caused by Malassezia furfur (Pityrosporum orbiculare); in the treatment of cutaneous candidiasis caused by Candida spp. and in the treatment of seborrheic dermatitis.


Nizral Cream (Generic Ketoconazole Cream ) - Preparations

Nizral Cream is available as tubes of 15 g .


Nizral Cream - Storage Requirements

Nizral Cream is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Ketoconazole Cream (Nizral Cream) - Uses

Generic Ketoconazole Cream in the form of Nizral Cream is used to treat skin infections.Generic Ketoconazole Cream which has the active ingredient Ketoconazole is also sold as Nizoral Cream and under various other brand names.


Nizral Cream (Generic Ketoconazole Cream)- Dosage

Cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, and tinea (pityriasis) versicolor:
Nizral cream, 2% should be applied once daily to cover the affected and immediate surrounding area.
Seborrheic dermatitis:
Nizral cream, 2% should be applied to the affected area twice daily for four weeks or until clinical clearing.




CONDITIONS FREQUENCYDURATION
Tinea pedisonce daily4-6 weeks
Tinea corporisonce daily 3-4 weeks
Tinea cruris once daily 2-4 weeks
Tinea versicolor once daily 2-3 weeks
Cutaneous candidiasis once daily 2-3 weeks
Seborrheic dermatitistwice daily 4 weeks

More resistant cases may be treated twice daily depending on patient response. The full course of therapy should be followed to reduce the possibility of recurrence.



Side Effects Of Nizral cream

Nizral cream 2% is generally well tolerated by the skin.The most common side effects of are severe irritation, pruritus and stinging. Less common side effects that may occur are painful allergic reactions.

Sunday, June 26, 2011

Lasix Tablets | Furosemide | Lasix Dosage & Uses | Side effects

Furosemide (Lasix Tablets) - Active Ingredient And Chemical structure

The active ingredient contained in Lasix Tablets for oral administration is Furosemide. Furosemide is a white to off-white odorless crystalline powder which is insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions. The structure is shown below
Structure Of Furosemide


Generic Forms and Brand names of Furosemide

Lasix Tablets manufactured by Sanofi-Aventis, India is an effective treatment for edema as well as hypertension.


Lasix Tablets - Preparations

Lasix is available as tablets of 40 mg .


Lasix Tablets - Storage Requirements

Lasix Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Furosemide (Lasix Tablets) - Uses

Furosemide in the form of Lasix Tablets is used in adults and pediatric patients to treat edema that is associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Lasix is extremely useful when a medication with greater diuretic potential is desired.
Lasix may also be used for the treatment of hypertension in adults alone or in combination with other anti hypertensive agents.


Lasix Tablets - Dosage

Lasix dosage varies as per patient response to gain maximal therapeutic response and should be given the minimal dose required to maintain that response.
Edema:
Adult Patients:The usual initial dose of Lasix for Adults is 20 to 80 mg given as a single dose. In case required, the same dose can be administered 6 to 8 hours later or the dose may be increased.The dose may be increased by 20 or 40 mg and given not sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained.Edema may be most efficiently and safely mobilized by giving Lasix on 2 to 4 consecutive days each week.
Pediatric patients:The usual initial dose of oral Lasix in pediatric patients is 2 mg/kg body weight, given as a single dose. If the diuretic response is not satisfactory after the Initial dose, dosage may be increased by 1 or 2 mg/kg no sooner than 6 to 8 hours after the previous dose.
Hypertension:
Therapy should be individualized according to the patient's response to gain maximum therapeutic response and to determine the minimal dose needed to maintain the therapeutic response. In case of adults the usual initial dose of Lasix for hypertension is 80 mg, usually divided into 40 mg twice a day. Dosage should then be adjusted according to response.


Lasix Tablets - Contraindications

Lasix is contraindicated in patients with anuria and in patients with a history of hypersensitivity to furosemlde.


Side Effects Of Lasix Tablets

The most common side effects of are (categorized by Organ System)
Gastro Intestinal System Reactions:

  • hepatic encephalopathy In patients with hepatocellular Insufficiency

  • pancreatitis

  • jaundice (Intrahepatic cholestatic jaundice)

  • Increased liver enzymes

  • anorexia

  • oral and gastric Irritation

  • cramping

  • diarmea

  • constipation

  • nausea

  • vomiting
Systemic Hypersensitivity Reactions:

  • Severe anaphylactic or anaphylactold reactions (e,g. with shock)

  • systemic vasculltis

  • Interstitial nephritis

  • necrotlzing anglltrs

Central Nervous System Reactions
  • tinnitus and hearing loss

  • parestheslas

  • vertigo

  • dizziness

  • headache

  • blurred vision

  • xanthopsia
Hematologic Reactions
  • aplastic anemia

  • thromtaocytopenia

  • agranulocytosis

  • hemolytic anemia

  • leukopenia

  • anemia

  • eosinophilia
Dermatologic-Hypersensitivity Reactions
  • exfoliatlve dermatitis

  • bullous pemphlgoid

  • erythema multiforme

  • purpura

  • photosensitivity

  • urticaria

  • rash

  • pruritus

  • Stevens-Johnson Syndrome

  • toxic epidermal necrolysis
Cardiovascular Reaction
  • Orthostatic hypotension may occur and be aggravated by alcohol, barbiturates or narcotics.
  • Increase in cholesterol and triglyceride serum levels
Other Reactions
  • hyperglycemia

  • glycosuria

  • hyperuricemia

  • muscle spasm

  • weakness

  • restlessness

  • urinary bladder spasm

  • thrombophlebitis

  • fever
Whenever adverse reactions are moderate or severe, LASIX dosage should be reduced or therapy withdrawn



Lasix Tablets - Overdosage

The main signs and symptoms of overdose with Lasix are dehydration, blood volume reduction, hypotension, electrolyte imbalance, hvpokalemia and hvoochloremic alkalosis.


Further Information

Prescribing Information