Licab Tablets | Generic Eskalith | Dosage | Uses | Side effects

Licab Tablets (Generic Eskalith) - Active Ingredient And Chemical structure

The active ingredient contained in Licab Tablets (Generic Eskalith) is lithium carbonate, a white, light alkaline powder with molecular formula Li₂CO₃.

Licab Tablets (Generic Eskalith) - Uses

Generic Eskalith (Lithium Carbonate) in the form of Licab Tablets is used in the treatment of manic episodes of manic depressive illness. Licab Maintenance therapy prevents or diminishes the intensity of subsequent episodes in those manic-depressive patients with a history of mania. Typical mania symptoms include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness and possibly hostility.

Generic Forms and Brand names of Eskalith (Lithium Carbonate)

Licab Tablets manufactured by Torrent Pharmaceuticals Ltd., India is an effective treatment for mood stabilizing, primarily in the treatment of bipolar disorder, treatment of depression and particularly of mania, both acutely and in the long term. Eskalith which has the active ingredient Lithium Carbonate is also sold as Lithane, Lithonate, Lithotabs, Lithobid and under various other brand names.

Licab Tablets (Generic Eskalith) - Preparations

Licab Tablets are available as tablets of 300mg and 400 mg (extended controlled release) .

Licab Tablets (Generic Eskalith) - Storage Requirements

Licab Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.

Licab Tablets (Generic Eskalith) - Warnings

Licab (Lithium Carbonate) should generally not be given to persons with significant renal or cardiovascular disease, severe debilitation or dehydration, or sodium depletion, since the risk of lithium toxicity is very high in such patients.
It should also be kept in mind that the ability to tolerate lithium is greater during the acute manic phase and decreases when manic symptoms subside. Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity.

Licab Tablets (Generic Eskalith) - Dosage

The dosage of Licab tablets is individualized as per the serum levels and the patients clinical response. For the treatment of Acute Mania, Optimal patient response to Licab can usually be established and maintained with 1,800 mg per day in divided doses.

Side Effects Of Licab Tablets (Generic Eskalith)

The most common side effects of Licab that may occur during initial therapy for the acute manic phase, and may persist throughout treatment are Fine hand tremor, polyuria, and mild thirst. Transient and mild nausea and general discomfort may also occur during the first few days of lithium administration. These side effects usually subside with continued treatment or a temporary reduction or cessation of dosage. Less common side effects that may occur at lithium levels below 2.0 mEq/L are Diarrhea, vomiting, drowsiness, muscular weakness, and lack of coordination.

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Prescribing Information

Syndopa Tablets | Generic Sinemet | Dosage | Syndopa Side effects

Syndopa ( Generic Sinemet) - Active Ingredient And Chemical structure

Syndopa ( Generic Sinemet) is a combination of carbidopa and levodopa for the treatment of Parkinson's disease and syndrome.The active ingredient contained in Syndopa are Carbidopa and Levodopa. Carbidopa is is a white, crystalline compound which is slightly soluble in water. Levodopa which is a white crystalline compound is an aromatic amino acid, that is also slightly soluble in water. The structures are shown below


Structure Of Carbidopa


Structure Of Levodopa

Syndopa Tablets ( Generic Sinemet) - Uses

Generic Sinemet in the form of Syndopa Tablets is used to treat the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication. Syndopa is indicated in these conditions to permit the administration of lower doses of levodopa with reduced nausea and vomiting, with more rapid dosage titration, with a somewhat smoother response, and with supplemental pyridoxine (vitamin B6).

Syndopa Tablets ( Generic Sinemet) - Contraindications

Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with Syndopa Tablets . They (MAO inhibitors) must be discontinued at least two weeks prior to initiating therapy with Syndopa.Syndopa is contraindicated in patients with known hypersensitivity to any component of this drug, and in patients with narrow-angle glaucoma.
Because levodopa may activate a malignant melanoma, Syndopa should not be used in patients with suspicious, undiagnosed skin lesions or a history of melanoma.

Generic Forms and Brand names of Sinemet (combination of Carbidopa and Levodopa)

Syndopa manufactured by SUN Pharmaceuticals , India is an effective treatment for the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication. Sinemet which has the active ingredients Carbidopa and Levodopa is also sold as Stalevo, Parcopa, Atamet and under various other brand names.

Syndopa Tablets ( Generic Sinemet) - Preparations

Syndopa Tablets are available in tablets which are a combination of Levodopa 100 mg & Carbidopa 10 mg, Levodopa 100 mg & Carbidopa 25 mg, Levodopa 200 mg & Carbidopa 50 mg and Levodopa 250 mg & Carbidopa 25 mg.

Syndopa Tablets ( Generic Sinemet) - Storage Requirements

Syndopa Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Syndopa Tablets ( Generic Sinemet) - Dosage

The optimum daily dosage of Syndopa Tablets must be determined by careful titration in each patient. Syndopa tablets are available in a 1:4 ratio of carbidopa to levodopa (Syndopa 25-100) as well as 1:10 ratio (Syndopa 25-250 and Syndopa 10-100).
Dosage is best initiated with one tablet of Syndopa 25-100 three times a day. This dosage schedule provides 75 mg of carbidopa per day. Dosage may be increased by one tablet every day or every other day, as necessary, until a dosage of eight tablets of Syndopa 25-100 a day is reached. If Syndopa 10-100 is used, dosage may be initiated with one tablet three or four times a day. Dosage may be increased by one tablet every day or every other day until a total of eight tablets (2 tablets, four times a day) is reached.

Syndopa Side Effects

The most common side effects of Syndopa Tablets ( Generic Sinemet) include dyskinesias, such as choreiform, dystonic, and other involuntary movements and nausea. Less common side effects that may occur during Syndopa Therapy are:
Body as a Whole: chest pain, asthenia.
Cardiovascular: cardiac irregularities, hypotension, orthostatic effects including orthostatic hypotension, hypertension, syncope, phlebitis, palpitation.
Gastrointestinal: dark saliva, gastrointestinal bleeding, development of duodenal ulcer, anorexia, vomiting, diarrhea, constipation, dyspepsia, dry mouth, taste alterations.
Hematologic: agranulocytosis, hemolytic and non-hemolytic anemia, thrombocytopenia, leukopenia.
Hypersensitivity: angioedema, urticaria, pruritus, Henoch-Schonlein purpura, bullous lesions (including pemphigus-like reactions).
Musculoskeletal: back pain, shoulder pain, muscle cramps.
Nervous System/Psychiatric: psychotic episodes including delusions, hallucinations, and paranoid ideation, neuroleptic malignant syndrome , bradykinetic episodes ("on-off" phenomenon), confusion, agitation, dizziness, somnolence, dream abnormalities including nightmares, insomnia, paresthesia, headache, depression with or without development of suicidal tendencies, dementia, pathological gambling, increased libido including hypersexuality, impulse control symptoms.
Respiratory: dyspnea, upper respiratory infection.
Skin: rash, increased sweating, alopecia, dark sweat.
Urogenital: urinary tract infection, urinary frequency, dark urine.

Further Information

Prescribing Information

Gravol Tablets | Dimenhydrinate | Dosage | Uses | Side effects

Gravol Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Gravol Tablets is Dimenhydrinate. Dimenhydrinate is a salt of two medications namely diphenhydramine, and 8-chlorotheophylline. The structures are shown below


Structure Of Diphenhydramine


Structure Of 8-chlorotheophylline

Generic Forms and Brand names of Gravol

Gravol Tablets is manufactured by Wallace Pharmaceuticals Pvt. Ltd, India. Gravol is an antihistamine which is recommended for the prevention and relief of nausea, vertigo and vomiting in motion sickness. Gravol which has the active ingredient Dimenhydrinate is also sold as Dramamine, Driminate, Gravol, Gravamin, Vomex, Vertirosan, Viabom,Dramin, Anautin and Daedalon and under various other brand names.

Gravol Tablets - Preparations

Gravol is available as tablets of 50 mg .

Gravol Tablets - Storage Requirements

Gravol Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Gravol Tablets - Uses

Dimenhydrinate in the form of Gravol Tablets is used for the prevention and treatment of various forms of motion sickness, Meniere's syndrome, vertigo due to other labyrinthine disorders, postoperative vomiting, medication induced nausea and vomiting associated with radiation therapy, and migraine.

Gravol Tablets - Dosage

The recommended adult dose of the tablets is 50 mg to 100 mg taken every 4 to 6 hours as needed. Do not take more than 400 mg in a 24-hour period. For prevention of motion sickness, you have to take the first dose of Gravol 30 minutes to 1 hour before you travel.

Side Effects Of Gravol Tablets

The most common side effects of are drowsiness, excitement or hyperactivity (especially in children), headache, new or worsening dizziness, blurred vision, ringing in the ears, dry mouth, nose, or throat, problems with coordination, fainting, dizziness, nausea. Less common but serious side effects that may occur are fast, pounding, or irregular heartbeat. In case of a serious side effect please inform your doctor immediately.