Friday, July 29, 2011

Licab Tablets | Generic Eskalith | Dosage | Uses | Side effects

Licab Tablets (Generic Eskalith) - Active Ingredient And Chemical structure

The active ingredient contained in Licab Tablets (Generic Eskalith) is lithium carbonate, a white, light alkaline powder with molecular formula Li2CO3.


Licab Tablets (Generic Eskalith) - Uses

Generic Eskalith (Lithium Carbonate) in the form of Licab Tablets is used in the treatment of manic episodes of manic depressive illness. Licab Maintenance therapy prevents or diminishes the intensity of subsequent episodes in those manic-depressive patients with a history of mania. Typical mania symptoms include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness and possibly hostility.


Generic Forms and Brand names of Eskalith (Lithium Carbonate)

Licab Tablets manufactured by Torrent Pharmaceuticals Ltd., India is an effective treatment for mood stabilizing, primarily in the treatment of bipolar disorder, treatment of depression and particularly of mania, both acutely and in the long term. Eskalith which has the active ingredient Lithium Carbonate is also sold as Lithane, Lithonate, Lithotabs, Lithobid and under various other brand names.


Licab Tablets (Generic Eskalith) - Preparations

Licab Tablets are available as tablets of 300mg and 400 mg (extended controlled release) .


Licab Tablets (Generic Eskalith) - Storage Requirements

Licab Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.


Licab Tablets (Generic Eskalith) - Warnings

Licab (Lithium Carbonate) should generally not be given to persons with significant renal or cardiovascular disease, severe debilitation or dehydration, or sodium depletion, since the risk of lithium toxicity is very high in such patients.
It should also be kept in mind that the ability to tolerate lithium is greater during the acute manic phase and decreases when manic symptoms subside. Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity.


Licab Tablets (Generic Eskalith) - Dosage

The dosage of Licab tablets is individualized as per the serum levels and the patients clinical response. For the treatment of Acute Mania, Optimal patient response to Licab can usually be established and maintained with 1,800 mg per day in divided doses.


Side Effects Of Licab Tablets (Generic Eskalith)

The most common side effects of Licab that may occur during initial therapy for the acute manic phase, and may persist throughout treatment are Fine hand tremor, polyuria, and mild thirst. Transient and mild nausea and general discomfort may also occur during the first few days of lithium administration. These side effects usually subside with continued treatment or a temporary reduction or cessation of dosage. Less common side effects that may occur at lithium levels below 2.0 mEq/L are Diarrhea, vomiting, drowsiness, muscular weakness, and lack of coordination.


Further Information

Prescribing Information

Syndopa Tablets | Generic Sinemet | Dosage | Syndopa Side effects

Syndopa ( Generic Sinemet) - Active Ingredient And Chemical structure

Syndopa ( Generic Sinemet) is a combination of carbidopa and levodopa for the treatment of Parkinson's disease and syndrome.The active ingredient contained in Syndopa are Carbidopa and Levodopa. Carbidopa is is a white, crystalline compound which is slightly soluble in water. Levodopa which is a white crystalline compound is an aromatic amino acid, that is also slightly soluble in water. The structures are shown below

Structure Of Carbidopa
Structure Of Carbidopa

Structure Of  Levodopa
Structure Of Levodopa



Syndopa Tablets ( Generic Sinemet) - Uses

Generic Sinemet in the form of Syndopa Tablets is used to treat the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication. Syndopa is indicated in these conditions to permit the administration of lower doses of levodopa with reduced nausea and vomiting, with more rapid dosage titration, with a somewhat smoother response, and with supplemental pyridoxine (vitamin B6).



Syndopa Tablets ( Generic Sinemet) - Contraindications

Nonselective monoamine oxidase (MAO) inhibitors are contraindicated for use with Syndopa Tablets . They (MAO inhibitors) must be discontinued at least two weeks prior to initiating therapy with Syndopa.Syndopa is contraindicated in patients with known hypersensitivity to any component of this drug, and in patients with narrow-angle glaucoma.
Because levodopa may activate a malignant melanoma, Syndopa should not be used in patients with suspicious, undiagnosed skin lesions or a history of melanoma.



Generic Forms and Brand names of Sinemet (combination of Carbidopa and Levodopa)

Syndopa manufactured by SUN Pharmaceuticals , India is an effective treatment for the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism, and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication and/or manganese intoxication. Sinemet which has the active ingredients Carbidopa and Levodopa is also sold as Stalevo, Parcopa, Atamet and under various other brand names.


Syndopa Tablets ( Generic Sinemet) - Preparations

Syndopa Tablets are available in tablets which are a combination of Levodopa 100 mg & Carbidopa 10 mg, Levodopa 100 mg & Carbidopa 25 mg, Levodopa 200 mg & Carbidopa 50 mg and Levodopa 250 mg & Carbidopa 25 mg.


Syndopa Tablets ( Generic Sinemet) - Storage Requirements

Syndopa Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Syndopa Tablets ( Generic Sinemet) - Dosage

The optimum daily dosage of Syndopa Tablets must be determined by careful titration in each patient. Syndopa tablets are available in a 1:4 ratio of carbidopa to levodopa (Syndopa 25-100) as well as 1:10 ratio (Syndopa 25-250 and Syndopa 10-100).
Dosage is best initiated with one tablet of Syndopa 25-100 three times a day. This dosage schedule provides 75 mg of carbidopa per day. Dosage may be increased by one tablet every day or every other day, as necessary, until a dosage of eight tablets of Syndopa 25-100 a day is reached. If Syndopa 10-100 is used, dosage may be initiated with one tablet three or four times a day. Dosage may be increased by one tablet every day or every other day until a total of eight tablets (2 tablets, four times a day) is reached.


Syndopa Side Effects

The most common side effects of Syndopa Tablets ( Generic Sinemet) include dyskinesias, such as choreiform, dystonic, and other involuntary movements and nausea. Less common side effects that may occur during Syndopa Therapy are:
Body as a Whole: chest pain, asthenia.
Cardiovascular: cardiac irregularities, hypotension, orthostatic effects including orthostatic hypotension, hypertension, syncope, phlebitis, palpitation.
Gastrointestinal: dark saliva, gastrointestinal bleeding, development of duodenal ulcer, anorexia, vomiting, diarrhea, constipation, dyspepsia, dry mouth, taste alterations.
Hematologic: agranulocytosis, hemolytic and non-hemolytic anemia, thrombocytopenia, leukopenia.
Hypersensitivity: angioedema, urticaria, pruritus, Henoch-Schonlein purpura, bullous lesions (including pemphigus-like reactions).
Musculoskeletal: back pain, shoulder pain, muscle cramps.
Nervous System/Psychiatric: psychotic episodes including delusions, hallucinations, and paranoid ideation, neuroleptic malignant syndrome , bradykinetic episodes ("on-off" phenomenon), confusion, agitation, dizziness, somnolence, dream abnormalities including nightmares, insomnia, paresthesia, headache, depression with or without development of suicidal tendencies, dementia, pathological gambling, increased libido including hypersexuality, impulse control symptoms.
Respiratory: dyspnea, upper respiratory infection.
Skin: rash, increased sweating, alopecia, dark sweat.
Urogenital: urinary tract infection, urinary frequency, dark urine.


Further Information

Prescribing Information

Thursday, July 21, 2011

Gravol Tablets | Dimenhydrinate | Dosage | Uses | Side effects

Gravol Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Gravol Tablets is Dimenhydrinate. Dimenhydrinate is a salt of two medications namely diphenhydramine, and 8-chlorotheophylline. The structures are shown below

Structure Of Diphenhydramine
Structure Of Diphenhydramine

Structure Of  8-chlorotheophylline
Structure Of 8-chlorotheophylline


Generic Forms and Brand names of Gravol

Gravol Tablets is manufactured by Wallace Pharmaceuticals Pvt. Ltd, India. Gravol is an antihistamine which is recommended for the prevention and relief of nausea, vertigo and vomiting in motion sickness. Gravol which has the active ingredient Dimenhydrinate is also sold as Dramamine, Driminate, Gravol, Gravamin, Vomex, Vertirosan, Viabom,Dramin, Anautin and Daedalon and under various other brand names.


Gravol Tablets - Preparations

Gravol is available as tablets of 50 mg .


Gravol Tablets - Storage Requirements

Gravol Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Gravol Tablets - Uses

Dimenhydrinate in the form of Gravol Tablets is used for the prevention and treatment of various forms of motion sickness, Meniere's syndrome, vertigo due to other labyrinthine disorders, postoperative vomiting, medication induced nausea and vomiting associated with radiation therapy, and migraine.


Gravol Tablets - Dosage

The recommended adult dose of the tablets is 50 mg to 100 mg taken every 4 to 6 hours as needed. Do not take more than 400 mg in a 24-hour period. For prevention of motion sickness, you have to take the first dose of Gravol 30 minutes to 1 hour before you travel.


Side Effects Of Gravol Tablets

The most common side effects of are drowsiness, excitement or hyperactivity (especially in children), headache, new or worsening dizziness, blurred vision, ringing in the ears, dry mouth, nose, or throat, problems with coordination, fainting, dizziness, nausea. Less common but serious side effects that may occur are fast, pounding, or irregular heartbeat. In case of a serious side effect please inform your doctor immediately.

Wednesday, July 20, 2011

Betaloc Tablets | Generic Toprol XL | Dosage | Uses | Side effects

Betaloc Tablets (Generic Toprol XL) - Active Ingredient And Chemical structure

The active ingredient contained in Generic Toprol XL is Metoprolol Succinate. Metoprolol succinate is a white crystalline powder which freely soluble in water. The structure is shown below
Structure Of Metoprolol


Generic Forms and Brand names of Toporol-XL


Betaloc Tablets manufactured by Astra Zeneca, India is an effective treatment for Hypertension, Angina Pectoris, Heart Failure(for the treatment of stable, symptomatic (NYHA Class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin). Toprol XL which has the active ingredient Metoprolol Succinate is also sold as Lopressor, Metoprolol Succinate, Prolomet, Metoprolol Tartrate and under various other brand names.


Betaloc Tablets - Preparations

Betaloc is available as tablets of 50 mg and 100 mg .


Betaloc Tablets - Storage Requirements

Betaloc Tablets are to be stored at room temperature (15°C to 30°C). Keep away from heat, moisture, and light.


Betaloc Tablets - Uses

Generic Toprol-XL in the form of Betaloc Tablets, for oral administration, available as extended release tablets is used to treat a number of cardiovascular indications including the treatment of hypertension, angina pectoris, cardiac arrhythmias, as secondary prevention post myocardial infarction and in heart failure.


Betaloc Tablets - Contraindications

Betaloc Tablets (Generic Toprol XL) are contraindicated in persons that have:
Known hypersensitivity to product components.
Severe bradycardia.
Heart block greater than first degree.
Cardiogenic shock.
Decompensated cardiac failure.
Sick sinus syndrome without a pacemaker.


Betaloc Tablets - Dosage

The dose of Betaloc Tablets has to be administered once daily. It is highly recommended that the dosing of Betaloc Tablets (Generic Toporol-XL) should be individualized.
Heart Failure:
The recommended starting dose is 12.5 mg or 25 mg doubled every two weeks to the highest dose tolerated or up to 200 mg.
Hypertension:
The usual initial dosage is 25 to 100 mg once daily. The dosage may be increased at weekly (or longer) intervals until optimum blood pressure reduction is achieved.
Angina Pectoris:
The usual initial dosage is 100 mg once daily. Gradually increase the dosage at weekly intervals until optimum clinical response has been obtained or there is an unacceptable bradycardia.


Side Effects Of Betaloc Tablets (Generic Toporol-XL)

The most common side effects of Betaloc Tablets (Generic Toporol-XL) are tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus, rash.


Further Information


More information on Toprol XL is available in the Prescribing Information

Tuesday, July 19, 2011

Atorlip Tablets | Generic Lipitor | Uses | Dosage | Side effects

Atorlip Tablets (Generic Lipitor) - Active Ingredient And Chemical structure

The active ingredient contained in Generic Lipitor Tablets is Atorvastatin Calcium . Atorvastatin calcium is a white to off-white crystalline powder that is is very slightly soluble in distilled water. The structure is shown below

Structure Of Atorvastatin Calcium


Atorlip Tablets (Generic Lipitor) - Uses


Generic Lipitor in the form of Atorlip Tablets is used for
1.Prevention of Cardiovascular Disease
In adult patients who do not have clinically evident coronary heart disease, but have multiple risk factors for coronary heart disease such as age, smoking, hypertension, low HDL-C, or a family history of early coronary heart disease, Atorlip Tablets are indicated to:
•Reduce the risk of myocardial infarction
•Reduce the risk of stroke
•Reduce the risk for revascularization procedures and angina
In patients with type 2 diabetes, and without clinically evident coronary heart disease , but have multiple risk factors for coronary heart disease such as retinopathy, albuminuria, smoking, or hypertension, Atorlip is indicated to:
•Reduce the risk of myocardial infarction
•Reduce the risk of stroke
In patients with clinically evident coronary heart disease, LIPITOR is indicated to:
•Reduce the risk of non-fatal myocardial infarction
•Reduce the risk of fatal and non-fatal stroke
•Reduce the risk for revascularization procedures
•Reduce the risk of hospitalization for CHF
•Reduce the risk of angina
2. Hyperlipidemia
Atorlip Tablets are indicated:
*As an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson Types IIa and IIb);
*As an adjunct to diet for the treatment of patients with elevated serum TG levels (Fredrickson Type IV);
*For the treatment of patients with primary dysbetalipoproteinemia (Fredrickson Type III) who do not respond adequately to diet;
*To reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable;
* As an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the following findings are present:
a.LDL-C remains = 190 mg/dL or
b.LDL-C remains = 160 mg/dL and:
•there is a positive family history of premature cardiovascular disease or
•two or more other CVD risk factors are present in the pediatric patient


Atorlip Tablets (Generic Lipitor) - Preparations

Atorlip is available as tablets of 5 mg, 10 mg, 20 mg and 40 mg. Each film coated tablet contains Atorvastatin calcium equivalent to Atorvastatin 5 mg, 10 mg, 20 mg and 40 mg respectively.



Generic Forms and Brand names of Lipitor (Atorvastatin Calcium)

Atorlip Tablets manufactured by Cipla Ltd., India is an effective treatment for prevention of Cardiovascular Disease in adult patients without clinically evident Coronary heart disease (CHD) , but with multiple risk factors for CHD. It is also used for the treatment of Hypercholesterolemia , and in n patients with type 2 diabetes and In patients with clinically evident CHD to reduce the risk of myocardial infarction. Generic Lipitor which has the active ingredient Atorvastatin Calcium is also sold as Atoris, Lipvas, Sortis, Torvast, Torvacard, Tortalip, Tulip and under various other brand names.



Atorlip Tablets (Generic Lipitor) - Storage Requirements

Atorlip Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.


Atorlip Tablets (Generic Lipitor) - Contraindications

Atorlip Tablets are contraindicated in the following cases:
1.Patients having Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels
2.Women who are pregnant or may become pregnant
3.Nursing mothers
4.Hypersensitivity to any component of this medication


Atorlip Tablets (Generic Lipitor) - Dosage


The Adult Dose range for Generic Lipitor tablets 10 to 80 mg once daily. The recommended starting dose of Atorlip is 10 or 20 mg once daily for most adult patients. The recommended starting dose for Pediatric patients is 10 mg once daily with the maximum recommended dose at 20 mg once daily. Patients which require large LDL-C reduction (>45%) may start at 40 mg once daily.


Side Effects Of Atorlip Tablets (Generic Lipitor)

The most common side effects of Atorlip in patients are nasopharyngitis, arthralgia, diarrhea, pain in extremity, urinary tract infection, Dyspepsia, Nausea, Musculoskeletal pain, Muscle Spasms, Myalgia, Insomnia and Pharyngolaryngeal pain.


Further Information


Prescribing Information

Friday, July 15, 2011

Aldactone Tablets | Spironolactone | Dosage | Uses | Aldactone Side effects

Aldactone Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Aldactone Tablets is Spironolactone. Spironolactone is practically insoluble in water, soluble in alcohol, and freely soluble in benzene and in chloroform. The structure is shown below
Structure Of  Spironolactone


Generic Forms and Brand names of Spironolactone


Aldactone Tablets manufactured by RPG Life Science Ltd., India is an effective treatment for edema and ascites of congestive heart failure, hepatic cirrhosis, the nephrotic syndrome, and idiopathic edema as well as that due to malignant effusions especially if not responding well to conventional diuretics.
Aldactone is also indicated for lowering blood pressure in essential hypertension, correcting hypokalemic alkalosis in severe hypertension and in the treatment of myasthenia gravis. Aldactone which has the active ingredient Spironolactone is also sold as Novo-Spiroton, Aldactazide, Spiractin, Spirotone, Verospiron, Berlactone and under various other brand names.


Aldactone Tablets Preparations

Aldactone Tablets is available as tablets of 25 mg and 100 mg . Aldactone oral tablets contain 25 mg or 100 mg of the active ingredient spironolactone respectively.


Aldactone Tablets - Storage Requirements

Aldactone Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Aldactone Tablets - Uses

Spironolactone in the form of Aldactone Tablets is used in the short term preoperative treatment of patients with primary hyperaldosteronism. Used for the long term maintenance therapy for patients with discrete aldosterone-producing adrenal adenomas who are judged to be poor operative risks or who decline surgery.
Aldactone (spironolactone) is also used in the management of Edematous conditions for patients with:
Congestive heart failure: For the management of edema and sodium retention when the patient is only partially responsive to, or is intolerant of, other therapeutic measures.
Cirrhosis of the liver accompanied by edema and/or ascites: Aldactone is indicated for maintenance therapy together with bed rest and the restriction of fluid and sodium.
The nephrotic syndrome:For nephrotic patients when treatment of the underlying disease, restriction of fluid and sodium intake, and the use of other diuretics do not provide an adequate response.
Essential hypertension: Usually in combination with other drugs, Aldactone is indicated for patients who cannot be treated adequately with other agents or for whom other agents are considered inappropriate.
Hypokalemia:For the treatment of patients with hypokalemia when other measures are considered inappropriate or inadequate. Aldactone is also indicated for the prophylaxis of hypokalemia in patients taking digitalis when other measures are considered inadequate or inappropriate.
Severe heart failure:To increase survival, and to reduce the need for hospitalization for heart failure when used in addition to standard therapy.


Aldactone Tablets - Contraindications and Warnings

Aldactone is contraindicated for patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, or hyperkalemia.
Potassium supplementation, either in the form of medication or as a diet rich in potassium, should not ordinarily be given in association with Aldactone therapy.
All patients receiving diuretic therapy should be observed for evidence of fluid or electrolyte imbalance, e.g., hypomagnesemia, hyponatremia, hypochloremic alkalosis, and hyperkalemia.



Aldactone Tablets - Dosage


Edema in adults (congestive heart failure, hepatic cirrhosis, or nephrotic syndrome).
An initial daily dosage of 100 mg of Aldactone administered in either single or divided doses is recommended, but may range from 25 to 200 mg daily.
Essential hypertension.
For adults, an initial daily dosage of 50 to 100 mg of Aldactone administered in either single or divided doses is recommended. Aldactone may also be given with diuretics which act more proximally in the renal tubule or with other antihypertensive agents. Treatment with Aldactone should be continued for at least two weeks, since the maximum response may not occur before this time.
Hypokalemia.
Aldactone in a dosage ranging from 25 mg to 100 mg daily is useful in treating a diuretic-induced hypokalemia, when oral potassium supplements or other potassium sparing regimens are considered inappropriate.
Severe heart failure (NYHA class III – IV).
Treatment should be initiated with Aldactone 25 mg once daily if the patient’s serum potassium is =5.0 mEq/L and the patient’s serum creatinine is = 2.5 mg/dL. Patients who tolerate 25 mg once daily may have their dosage increased to 50 mg once daily as clinically indicated. Patients who do not tolerate 25 mg once-daily dose may have their dosage reduced to 25 mg every other day.


Side Effects Of Aldactone Tablets


The most common side effects of Aldactone Tablets are
Digestive: Gastric bleeding, ulceration, gastritis, diarrhea and cramping, nausea, vomiting.
Endocrine: Gynecomastia (see Precautions), inability to achieve or maintain erection, irregular menses or amenorrhea, postmenopausal bleeding. Carcinoma of the breast has been reported in patients taking Aldactone but a cause and effect relationship has not been established.
Hematologic: Agranulocytosis.
Hypersensitivity: Fever, urticaria, maculopapular or erythematous cutaneous eruptions, anaphylactic reactions, vasculitis.
Metabolism: Hyperkalemia.
Nervous system /psychiatric: Mental confusion, ataxia, headache, drowsiness, lethargy.
Liver / biliary: A very few cases of mixed cholestatic/hepatocellular toxicity, with one reported fatality, have been reported with Aldactone administration.
Renal: Renal dysfunction (including renal failure).


Further Information


Physician Prescribing Information

Buscopan Tablets | Buscopan Plus | Dosage | Uses | Side effects

Buscopan Tablets (Hyoscine Butylbromide) - Active Ingredient And Chemical structure

The active ingredient contained in Buscopan Tablets and Buscopan Plus is Hyoscine Butylbromide. (In addition Buscopan Plus also contains Paracetamol). Hyoscine Butylbromide ia a white or almost white, odourless powder which is soluble 1 to 1 in water. The structure is shown below

Structure Of Hyoscine Butylbromide


Generic Forms and Brand names of Buscopan Tablets (Hyoscine Butyl Bromide)

Buscopan Tablets manufactured by German Remedies, India is an effective treatment for the relief of smooth muscle spasm of the gastrointestinal and genitourinary systems. Each 10 mg tablet of Buscopan contains 10 mg of Hyoscine Butylbromide. Buscopan Tablets which has the active ingredient Hyoscine Butylbromide is also sold under various other brand names. Buscopan Plus also manufactured by German Remedies, India contains Buscopan 10 mg and Paracetamol 500 mg.


Buscopan Tablets - Preparations


Buscopan Tablets is available as tablets of 10 mg.


Buscopan Tablets - Storage Requirements


Buscopan Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Buscopan Tablets - Contraindications


Hypersensitivity to hyoscine butylbromide, or atropinics or to any of the product inactive ingredients. Buscopan (hyoscine butylbromide) tablets are also contraindicated in patients with myasthenia gravis, megacolon, glaucoma or obstructive prostatic hypertrophy. Buscopan (hyoscine butylbromide) tablets should be used with caution in patients having prostatic enlargement. Buscopan may precipitate or aggravate urinary retention in patients which have the following conditions: nonobstructive prostatic hypertrophy, urinary retention (or the predisposition to) or obstructive uropathy such as a bladder neck obstruction due to prostatic hypertrophy.
Drugs that may interact with Buscopan include tricyclic antidepressants, antihistamines, quinidine, disopyramide, amantadine, MAO inhibitors, anticholinergics, dopamine antagonists such as metoclopramide, beta-adrenergic agents, antacids or adsorbent antidiarrheals.


Uses of Buscopan Tablets

Hyoscine Butylbromide in the form of Buscopan tablets is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity of the gastrointestinal and genitourinary systems. Buscopan Tablets are also used for preventing bladder spasms.


Buscopan Tablets - Dosage

The response to Buscopan (hyoscine butylbromide) may vary from person to person and therefore doses should be adjusted accordingly.Please ask your doctor for your exact dosing instructions. The normal dose of Buscopan is One to two 10 mg tablets per day up to a maximum of 6 tablets per day. In prolonged illness which requires repeated dosing, 1 tablet 3 to 5 times a day is recommended.Buscopan Tablets should be swallowed whole with a glass of water.


Buscopan Tablets - Missed Dosage

In case you miss a dose of Buscopan, take the next dose as scheduled. Do not double the dose.


Side Effects Of Buscopan Tablets


The most common side effects of Buscopan Tablets are Xerostomia (dry mouth), dyshidrosis, visual accomodation disorders, tachycardia, dyspnea, and urinary retention.
Rare side effects that may occur are dizziness, decrease in blood pressure flushing, Skin reactions and other hypersensitivity, angioedema and fixed drug eruptions. Other undesirable effects reported during therapy with Buscopan Tablets include increased pulse rate, diarrhea, nausea, retinal pigmentation, and glaucoma.


Further Information

Prescribing Information

Wednesday, July 13, 2011

Asprito Tablets | Generic Abilify | Dosage | Uses | Side effects

Generic Abilify Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Generic Abilify Tablets is Aripiprazole. The structure is shown below

Structure Of Aripiprazole


Generic Forms and Brand names of Abilify (Aripiprazole)

Asprito manufactured by Intas Pharmaceuticals Ltd., India is an effective treatment for schizophrenia, certain symptoms of bipolar disorder and clinical depression. Generic Abilify which has the active ingredient Aripiprazole is also sold as Aripiprex and under various other brand names.


Generic Abilify (Asprito Tablets ) - Preparations

Asprito is available as tablets of 10 mg, 15 mg, 20 mg and 30 mg .


Generic Abilify (Asprito Tablets ) - Storage Requirements

Asprito Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture and light.


Generic Abilify (Asprito Tablets) - Uses


Generic Abilify Tablets in the form of Asprito tablets is used for:
Treatment of Schizophrenia in adults and adolescents aged 13 to 17 years
Treatment of manic or mixed episodes associated with Bipolar I Disorder as monotherapy or adjunctive to lithium or valproate in adults and pediatric patients aged 10 to 17 years

Adjunctive treatment of Major Depressive Disorder in adults as an injection for:Treatment of adults with agitation associated with Schizophrenia or Bipolar I Disorder, manic or mixed episodes


Generic Abilify (Asprito Tablets ) - Dosage


The recommended doses for various treatments are given below:
Schizophrenia - adults
Initial Dose: 10-15 mg /day
Recommended Dose: 10-15 mg /day
Maximum Dose: 30 mg /day
Schizophrenia - adolescents
Initial Dose: 2 mg /day
Recommended Dose: 10 mg /day
Maximum Dose: 30 mg /day
Bipolar Mania - adults monotherapy or as an adjunct to lithium or valproate
Initial Dose: 15 mg /day
Recommended Dose: 15 mg /day
Maximum Dose: 30 mg /day
Bipolar Mania - pediatric patients monotherapy or as an adjunct to lithium or valproate
Initial Dose: 2 mg /day
Recommended Dose: 10 mg /day
Maximum Dose: 30 mg /day
As an adjunct to antidepressants for the treatment of Major Depressive Disorder
Initial Dose: 2-5 mg /day
Recommended Dose: 5-10 mg /day
Maximum Dose: 15 mg /day


Generic Abilify (Asprito Tablets ) - Contraindications

Generic Abilify is contraindicated in all persons with a known hypersensitivity to Aripiprazole or any non active ingredient.


Side Effects Of Generic Abilify (Asprito Tablets )

The most common side effects of Asprito Tablets are akathisia, extrapyramidal disorder, somnolence, and tremor, sedation, restlessness, tremor, fatigue, nausea, blurred vision, salivary hypersecretion, constipation and dizziness.


Further Information


Prescribing Information

Generic Tamoxifen Tablets | Tamtero | Nolvadex Tablets | Dosage | Uses | Side effects

Generic Tamoxifen Tablets - Active Ingredient And Chemical structure

The active ingredient contained in Generic Tamoxifen Tablets (also referred to as generic Nolvadex) is Tamoxifen Citrate. The structure is shown below

Structure  Of Tamoxifen Citrate


Generic Forms and Brand names of Nolvadex Tablets

Although Tamoxifen was discovered by ICI Pharmaceuticals (presently AstraZeneca) and is sold under the brand names Nolvadex, Istubal, and Valodex, the medication is still is widely referred to by its generic name "tamoxifen". Tamtero manufactured by Hetero Drugs Ltd, India is effective for treatment and prevention of breast cancer in men and women. Tamtero Tablets (tamoxifen citrate) Tablets, a nonsteroidal antiestrogen, are for oral administration. Generic Tamoxifen which has the active ingredient Tamoxifen Citrate is also sold as Istubal, Valodex, Tamoxifen Apo-Tamox; Gen-Tamoxifen, Novo-Tamoxifen, Tamofen, Tamone, Citofen, Crisafeno, Diemon, Istubol, Kessar, Noltam, Nourytam, Novo-Tamoxifen , Oncomox, PMS-Tamoxifen, Tamoxifene, Tamoxifen, Retaxim, Tamizam, Tamoxasta, Tamoxen, Valodex, Zemide, Tamoxifeno, Soltamox and under various other brand names.


Generic Tamoxifen Preparations

Generic Tamoxifen is available as Tamtero tablets of 10 mg. Each 10 mg tablet of Tamtero contains 15.2 mg of tamoxifen citrate which is equivalent to 10 mg of tamoxifen.


Generic Tamoxifen Tablets (Tamtero) - Storage Requirements

Tamtero Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Tamoxifen Tablets (Tamtero) - Uses


Generic Tamoxifen Tablets in the form of Tamtero Tablets is used to treat metastatic breast cancer adjuvant treatment of breast cancer, ductal carcinoma in situ as well as for reduction in breast cancer incidence in high risk women.
Metastatic Breast Cancer:
Generic Tamoxifen Tablets are effective in the treatment of metastatic breast cancer in women and men. In premenopausal women with metastatic breast cancer, Tamtero is an alternative to oophorectomy or ovarian irradiation.
Adjuvant Treatment of Breast Cancer:
Generic Tamoxifen Tablets are indicated for the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation.
Ductal Carcinoma in Situ (DCIS):
In women with DCIS, following breast surgery and radiation, Generic Tamoxifen Tablets are used to reduce the risk of invasive breast cancer
Reduction in Breast Cancer Incidence in High Risk Women:
Generic Tamoxifen Tablets are used to reduce the incidence of breast cancer in women at high risk for breast cancer.


Tamtero Tablets (Generic Tamoxifen) - Contraindications

Generic Tamoxifen is contraindicated in patients with known hypersensitivity to the drug or any of its ingredients.


Tamtero Tablets (Generic Tamoxifen) - Dosage


The recommended dosages of Tamtero Tablets (Generic Tamoxifen) are given below;
Breast Cancer:
For patients with breast cancer, the recommended daily dose is 20-40 mg. Dosages more than 20 mg per day should be given in divided doses (morning and evening).
Ductal Carcinoma in Situ (DCIS):
The recommended dose is Tamtero Tablets 20 mg daily for 5 years.
Reduction in Breast Cancer Incidence in High Risk Women:
The recommended dose is Tamtero Tablets 20 mg daily for 5 years.


Side Effects Of Generic Tamoxifen Tablets (Tamtero)

The most common side effects of Generic Tamoxifen Tablets are Hot Flashes, Vaginal Discharges, Vaginal Bleeding, Decreased Platelets count, Infection/Sepsis, Constipation, Alopecia, Allergy. Less frequently reported adverse reactions are vaginal bleeding, vaginal discharge, menstrual irregularities, skin rash and headaches. Most of the time these have not been of sufficient severity to require dosage reduction or discontinuation of treatment. Very rare reports of erythema multiforme, Stevens-Johnson syndrome, bullous pemphigoid, interstitial pneumonitis, hypersensitivity reactions including angioedema have been reported by patients undergoing treatment with Generic Tamoxifen.


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Monday, July 11, 2011

Plagril Tablets | Generic Plavix | Dosage | Uses | Side effects

Generic Plavix (Plagril Tablets) - Active Ingredient And Chemical structure

The active ingredient contained in Plagril Tablets is Clopidogrel Bisulfate. Clopidogrel bisulfate is a white to off-white powder. It is practically insoluble in water. The structure is shown below
Structure of Clopidogrel Bisulfate


Generic Forms and Brand names of Generic Plavix

Plagril manufactured by Dr. Reddy's Pharmaceuticals, India is an effective treatment to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Generic Plavix which has the active ingredient Clopidogrel Bisulfate is also sold under various other brand names.


Generic Plavix (Plagril Tablets) - Preparations

Plagril Tablets is available as oral tablets of 75 mg .


Plagril Tablets (Generic Plavix) - Storage Requirements

Plagril Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Generic Plavix (Plagril Tablets) - Uses

Generic Plavix, a P2Y12 platelet inhibitor in the form of Plagril tablets is used to treat:
Acute coronary syndrome
Patients with non-ST-segment elevation ACS
Patients with ST-elevation myocardial infarction (STEMI)
Recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease.


Plagril Tablets (Generic Plavix) - Dosage

The dosing for Generic Plavix is as follows:
Acute coronary syndrome
- Non-ST-segment elevation ACS (UA/NSTEMI): 300 mg loading dose followed by 75 mg once daily, in combination with aspirin (75-325 mg once daily)
- STEMI: 75 mg once daily, in combination with aspirin (75-325 mg once daily), with or without a loading dose and with or without thrombolytics
Recent MI, recent stroke, or established peripheral arterial disease: 75 mg once daily


Plagril Tablets (Generic Plavix) - Contraindications

Generic Plavix is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage. Plagril Tablets are also contraindicated in patients with hypersensitivity to Clopidogrel Bisulfate or any any inactive ingredient of the product.


Side Effects Of Plagril Tablets (Generic Plavix)

The most commonly reported side effects of Plagril Tablets are Bleeding, including life-threatening and fatal bleeding. Less common side effects that may occur are Severe neutropenia (low white blood cells), Thrombotic thrombocytopenic purpura (TTP), skin irritations, respiratory difficulties, bloody stools and vomit, bloating of facial features, limbs and joints, exhaustion.


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Thursday, July 7, 2011

Calutide Tablets | Generic Casodex | Dosage | Uses | Side effects

Calutide Tablets (Generic Casodex) - Active Ingredient And Chemical structure

The active ingredient contained in Calutide Tablets is bicalutamide. Bicalutamide is a fine white to off white powder which is practically insoluble in water but soluble in acetone and tetrahydrofuran. The structure is shown below

Structure Of Bicalutamide


Generic Forms and Brand names of Casodex Tablets (Bicalutamide)

Calutide Tablets manufactured by Cipla Ltd., India is an effective treatment for advanced prostate cancer in combination therapy with a luteinizing hormone-releasing hormone (LHRH) analog therapy. Generic Casodex which has the active ingredient Bicalutamide is also sold under various other brand names.


Calutide Tablets - Preparations

Calutide Tablets is available as tablets of 50 mg. Each film-coated tablet contains 50 mg of Bicalutamide.


Calutide Tablets - Storage Requirements

Calutide Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Calutide Tablets (Generic Casodex) - Uses

Generic Casodex in the form of Calutide Tablets is used for the treatment of advanced prostate cancer (D2 metastatic prostate cancer) in combination with LHRH analogue therapy.


Calutide Tablets - Dosage

The recommended dose for Calutide therapy in combination with an LHRH (luteinizing hormone-releasing hormone) analog is one 50 mg tablet once daily (either in the morning or evening), with or without food. It is recommended that Calutide be taken at the same time each day. Treatment with Calutide has to be started at the same time as the treatment with an LHRH analog.


Calutide Tablets - Contraindications

Calutide Tablets is contraindicated in any patient who has shown a hypersensitivity reaction to the medication or any of the tablet's components. It is also is contraindicated in women.


Side Effects Of Calutide Tablets (Generic Casodex)

The most common side effects of Calutide Tablets in combination with a LHRH-A are hot flashes, pain (including general, back, pelvic and abdominal), asthenia, constipation, infection, nausea, peripheral edema, dyspnea, diarrhea, hematuria, nocturia and anemia.


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Antiflu Capsules | Generic Tamiflu | Dosage | Uses | Side effects

Antiflu Capsules (Generic Tamiflu)- Active Ingredient And Chemical structure


The active ingredient contained in Antiflu Capsules is Oseltamivir Phosphate. Oseltamivir phosphate is a white crystalline solid. The structure is shown below

Structure Of Oseltamivir Phosphate


Generic Forms and Brand names of Tamiflu Capsules (Oseltamivir Phosphate)


Antiflu Capsules manufactured by Cipla Ltd, India has been used effectively to treat and prevent influenza A virus and influenza B virus infection. Generic Tamiflu Capsules which has the active ingredient Oseltamivir Phosphate is also sold under various other brand names.


Antiflu Capsules Preparations

Antiflu is available as capsules of 75 mg. Each capsule contains Oseltamivir phosphate equivalent to 75 mg of Oseltamivir.


Antiflu Capsules - Storage Requirements

Antiflu Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep out of reach of children and pets.


Uses of Antiflu Capsules (Generic Tamiflu)

Generic Tamiflu in the form of Antiflu Capsules is used to treat influenza viruses types A and B and against Swine Influenza Virus (SIV - SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H3N1, H3N2, and H2N3).


Antiflu Capsules Dosage

Standard Dosage – Treatment of Influenza

Adults and Adolescents
The recommended oral dose of Antiflu for treatment of influenza in adults and adolescents 13 years and older is 75 mg twice daily for 5 days. Treatment should begin within 2 days of onset of symptoms of influenza.
Pediatric Patients
Antiflu is not indicated for treatment of influenza in pediatric patients younger than 1 year. The recommended oral dose of Antiflu for pediatric patients 1 year and older is shown in Table 1 below.Antiflu oral suspension may also be used by patients who cannot swallow a capsule.


Table 1: Oral Dose of Antiflu for Treatment of Influenza in Pediatric Patients by Weight


Body Weight(kg)Body Weight(lbs)Recommended Dose for 5 Days
≤15 kg≤ 33 lbs30 mg twice daily
>15 kg to 23 kg>33 lbs to 51 lbs45 mg twice daily
>23 kg to 40 kg>51 lbs to 88 lbs60 mg twice daily
>40 kg>88 lbs75 mg twice daily


Standard Dosage – Prophylaxis of Influenza

Adults and Adolescents
The recommended oral dose of Antiflu for prophylaxis of influenza in adults and adolescents 13 years and older following close contact with an infected individual is 75 mg once daily for at least 10 days. Therapy should begin within 2 days of exposure. The recommended dose for prophylaxis during a community outbreak of influenza is 75 mg once daily. Safety and efficacy have been demonstrated for up to 6 weeks in immunocompetent patients. Safety has been demonstrated for up to 12 weeks in immunocompromised patients.The duration of protection lasts for as long as dosing is continued.
Pediatric Patients
The safety and efficacy of Antiflu for prophylaxis of influenza in pediatric patients younger than 1 year of age have not been established. The recommended oral dose of Antiflu for pediatric patients 1 year and older following close contact with an infected individual is shown in Table 2. Antiflu for oral suspension may also be used by patients who cannot swallow a capsule.


Table 2:Oral Dose of Antiflu for Prophylaxis of Influenza in Pediatric Patients by Weight


Body Weight(kg)Body Weight(lbs)Recommended Dose for 10 Days
≤15 kg≤ 33 lbs30 mg once daily
>15 kg to 23 kg>33 lbs to 51 lbs45 mg once daily
>23 kg to 40 kg>51 lbs to 88 lbs60 mg once daily
>40 kg>88 lbs75 mg once daily

Side Effects Of Antiflu Capsules


The most common side effects of Antiflu therapy are nausea, vomiting, diarrhea, abdominal pain, and headache. Rare ADRs include: hepatitis and elevated liver enzymes, rash, allergic reactions including anaphylaxis, and Stevens-Johnson syndrome. Less common and rarely occuring side effects that may occur are anaphylaxis and serious skin reactions including toxic epidermal necrolysis, Stevens-Johnson Syndrome,erythema multiforme, toxic epidermal necrolysis, cardiac arrhythmia, seizure, confusion, aggravation of diabetes, and haemorrhagic colitis.


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Friday, July 1, 2011

Megalis Tablets | Generic Cialis | Dosage | Uses | Side effects

Megalis Tablets (Generic Cialis)- Active Ingredient And Chemical structure

The active ingredient contained in Megalis Tablets is Tadalafil . The structure is shown below

Structure Of  Tadalafil


Generic Forms and Brand names of Tadalafil Tablets

Megalis Tablets manufactured by Macleods Pharmaceuticals, India is an effective treatment for erectile dysfunction. Generic Cialis which has the active ingredient Tadalafil is also sold as Tadacip manufactured by Cipla Ltd, India and under various other brand names.


Megalis Tablets - Preparations

Megalis Tablets is available as tablets of 10 mg and 20 mg .


Megalis Tablets - Storage Requirements

Megalis Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Store this medicine out of the reach of children and pets.


Megalis Tablets - Uses

Generic Cialis in the form of Megalis Tablets is used for the treatment of erectile dysfunction.


Megalis Tablets - Dosage

The recommended starting dose of Megalis Tablets (Generic Cialis) is is 10 mg, taken prior to anticipated sexual activity. It is to be used as and when required with or without food. The dose may be increased to 20 mg based on individual efficacy and tolerability. The maximum dosing frequency is once per day.


Megalis Tablets - Contraindications

Using Megalis Tablets to treat patients who are using any form of organic nitrate, either regularly and/or intermittently, is contraindicated. Generic Cialis (Megalis) is also contraindicated in patients with hypersensitivity to tadalafil. Treatments for erectile dysfunction, including Megalis, should not be used in men for whom sexual activity is not advisable because of their cardiovascular status.


Precautions And Warnings When Using Megalis Tablets

Patients should seek emergency treatment if an erection lasts for more than 4 hours. Megalis Tablets have to be used with caution in patients predisposed to priapism.


Side Effects Of Megalis Tablets

The most common side effects of Megalis Tablets are Headache, Dyspepsia, Back pain, Myalgia, Nasal congestion , Flushing and Pain in limb.


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