Friday, July 15, 2011

Buscopan Tablets | Buscopan Plus | Dosage | Uses | Side effects

Buscopan Tablets (Hyoscine Butylbromide) - Active Ingredient And Chemical structure

The active ingredient contained in Buscopan Tablets and Buscopan Plus is Hyoscine Butylbromide. (In addition Buscopan Plus also contains Paracetamol). Hyoscine Butylbromide ia a white or almost white, odourless powder which is soluble 1 to 1 in water. The structure is shown below

Structure Of Hyoscine Butylbromide


Generic Forms and Brand names of Buscopan Tablets (Hyoscine Butyl Bromide)

Buscopan Tablets manufactured by German Remedies, India is an effective treatment for the relief of smooth muscle spasm of the gastrointestinal and genitourinary systems. Each 10 mg tablet of Buscopan contains 10 mg of Hyoscine Butylbromide. Buscopan Tablets which has the active ingredient Hyoscine Butylbromide is also sold under various other brand names. Buscopan Plus also manufactured by German Remedies, India contains Buscopan 10 mg and Paracetamol 500 mg.


Buscopan Tablets - Preparations


Buscopan Tablets is available as tablets of 10 mg.


Buscopan Tablets - Storage Requirements


Buscopan Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Buscopan Tablets - Contraindications


Hypersensitivity to hyoscine butylbromide, or atropinics or to any of the product inactive ingredients. Buscopan (hyoscine butylbromide) tablets are also contraindicated in patients with myasthenia gravis, megacolon, glaucoma or obstructive prostatic hypertrophy. Buscopan (hyoscine butylbromide) tablets should be used with caution in patients having prostatic enlargement. Buscopan may precipitate or aggravate urinary retention in patients which have the following conditions: nonobstructive prostatic hypertrophy, urinary retention (or the predisposition to) or obstructive uropathy such as a bladder neck obstruction due to prostatic hypertrophy.
Drugs that may interact with Buscopan include tricyclic antidepressants, antihistamines, quinidine, disopyramide, amantadine, MAO inhibitors, anticholinergics, dopamine antagonists such as metoclopramide, beta-adrenergic agents, antacids or adsorbent antidiarrheals.


Uses of Buscopan Tablets

Hyoscine Butylbromide in the form of Buscopan tablets is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity of the gastrointestinal and genitourinary systems. Buscopan Tablets are also used for preventing bladder spasms.


Buscopan Tablets - Dosage

The response to Buscopan (hyoscine butylbromide) may vary from person to person and therefore doses should be adjusted accordingly.Please ask your doctor for your exact dosing instructions. The normal dose of Buscopan is One to two 10 mg tablets per day up to a maximum of 6 tablets per day. In prolonged illness which requires repeated dosing, 1 tablet 3 to 5 times a day is recommended.Buscopan Tablets should be swallowed whole with a glass of water.


Buscopan Tablets - Missed Dosage

In case you miss a dose of Buscopan, take the next dose as scheduled. Do not double the dose.


Side Effects Of Buscopan Tablets


The most common side effects of Buscopan Tablets are Xerostomia (dry mouth), dyshidrosis, visual accomodation disorders, tachycardia, dyspnea, and urinary retention.
Rare side effects that may occur are dizziness, decrease in blood pressure flushing, Skin reactions and other hypersensitivity, angioedema and fixed drug eruptions. Other undesirable effects reported during therapy with Buscopan Tablets include increased pulse rate, diarrhea, nausea, retinal pigmentation, and glaucoma.


Further Information

Prescribing Information