Cobese Capsules | Generic Xenical | Dosage | Uses | Side effects

Cobese Capsules (Generic Xenical) - Active Ingredient And Chemical structure

The active ingredient contained in Cobese Tablets is Orlistat. Orlistat is a white to off-white crystalline powder. Orlistat is practically insoluble in water, freely soluble in chloroform, and very soluble in methanol and ethanol. Orlistat is a lipase inhibitor which is used for obesity management. It acts by inhibiting the absorption of dietary fats. The structure is shown below

Cobese Capsules (Generic Xenical) - Uses

Generic Xenical in the form of Cobese Capsules is used for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet.
Generic Xenical is also used to reduce the risk for regaining weight after prior weight loss. Generic Xenical is indicated for obese patients with an initial body mass index (BMI) of greater than or equal to 30 kg/m2 or greater than or equal to 27 kg/m2 in the presence of other risk factors (eg, hypertension, diabetes, dyslipidemia).

Generic Forms and Brand names of Xenical

Cobese manufactured by Rambaxy Laboratories Ltd., India is an effective treatment for persons suffering from obesity, in its ability to manage adiposis in adult and adolescent patients. Xenical which has the active ingredient Orlistat is also sold as Alli, Orlimac, Vyfat, Orlistat and under various other brand names.

Cobese Capsules (Generic Xenical) - Preparations

Cobese is available as Capsules of 120 mg. Each capsule of Generic Xenical contains a pellet formulation consisting of 120 mg of the active ingredient, orlistat, as well as the inactive ingredients.

Cobese Capsules (Generic Xenical) - Storage Requirements

Cobese Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Cobese Capsules (Generic Xenical) - Dosage

The recommended dose of Generic Xenical is one 120 mg capsule three times a day with each main meal containing fat to be taken during or up to 1 hour after the meal. In case a meal is occasionally missed or contains no fat, the dose of Cobese can be omitted.

Cobese Capsules (Generic Xenical) - Contraindications

Cobese Capsules (Generic Xenical) is contraindicated in patients with chronic malabsorption syndrome or cholestasis, and in patients with known hypersensitivity to Orlistat or to any inactive component of this product.

Generic Xenical (Cobese Capsules) - Overdosage

Single doses of 800 mg of Orlistat (Generic Xenical) and multiple doses of up to 400 mg three times a day for 15 days have been studied in normal weight and obese subjects without significant adverse findings.

Side Effects Of Cobese Capsules (Generic Xenical)

The most common side effects of Cobese Capsules (Generic Xenical) are Oily Spotting, Flatus with Discharge, Fecal Urgency, Fatty/Oily Stool, Oily Evacuation, Increased Defecation and Fecal Incontinence.

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Champix Tablets | Varenicline Tartrate | Dosage | Uses | Side effects

Champix Tablets (Varenicline Tartrate) - Active Ingredient And Chemical structure

The active ingredient contained in Champix Tablets is varenicline tartrate. The structure is shown below

Champix Tablets (Varenicline Tartrate) - Uses

Varenicline Tartrate in the form of Champix Tablets is used to relieve the craving and withdrawal symptoms associated with stopping smoking.

Generic Forms and Brand names of Champix Tablets (Varenicline Tartrate)

Champix Tablets manufactured by Pfizer, India is an effective treatment for help to relieve the craving and withdrawal symptoms associated with stopping smoking. Champix which has the active ingredient varenicline tartrate is also sold as Chantix and under various other brand names.

Champix Tablets - Preparations

Champix Tablets is available as tablets of 0.5 mg and 1 mg.

Champix Tablets - Storage Requirements

Champix Tablets (Varenicline Tartrate) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Champix Tablets Dosage

Day 1 - 3
Take one white Champix 0.5 mg tablet once a day.

Day 4 - 7
Take one white Champix 0.5 mg tablet twice a day, once in the morning and once in the evening, at about the same time each day.

Week 2 (day 8) to the end of treatment: There are two dosing options

Day 8 to end of treatment 0.5 mg twice a day: Continue to take one white Champix 0.5 mg pill in the morning, and one in the evening, at about the same time each day

OR

1.0 mg twice a day

Day 8 to end of treatment

1.0 mg twice a day: Take one light blue CHAMPIX 1.0 mg pill in the morning, and one in the evening, at about the
same time each day

Champix Tablets - Warnings and Precautions

In case you develop any of the below mentioned while undergoing Champix therapy, call your doctor right away:

thoughts about suicide or dying, or attempts to commit suicide
new or worse depression, anxiety or panic attacks
feeling very agitated or restless
acting aggressive, being angry, or violent
acting on dangerous impulses
an extreme increase in activity and talking (mania)
abnormal thoughts or sensations
seeing or hearing things that are not there(hallucinations)
feeling people are against you (paranoia)
feeling confused
other unusual changes in behavior

Tell your doctor if you take: Insulin, Asthma medicines (theophylline) or Blood thinner (warfarin)

An adjustment of the dose of these medicines may be necessary once you are smoke-free.

Champix Tablets - Contraindications

Champix Tablets is contraindicated in individuals with hypersensitivity to varenicline tartrate or any of the other ingredients of the medication.
In Persons using nicotine replacement therapy, such as patches, gum or inhaler.
The combination of Champix Tablets and nicotine replacement therapy is not expected to improve your chances of quitting, and may result in more side effects than with Champix Tablets alone.

Side Effects Of Champix Tablets

Like all medicines, Champix Tablets can cause side effects, although all persons will not get them.The most common side effects of are Nausea, vomiting, Trouble sleeping, Headache, Abnormal dreams (vivid, unusual, or increased dreaming; rarely may include nightmares), Sleepiness, tiredness, dizziness, Constipation, diarrhea, gas.

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A-Ret Gel | Generic Retin-A Cream | Dosage | Uses | Side effects

A-Ret Gel (Generic Retin-A Cream) - Active Ingredient And Chemical structure

The active ingredient contained in A-Ret Gel (Generic Tretinoin Cream) is tretinoin also known as retinoic acid or vitamin A acid in either of two strengths, 0.025% or 0.05% or 0.1% by weight. It is a member of retinoid family of compounds. The structure is shown below

A-Ret Gel ( Generic Retin-A Cream) - Uses

Generic Retin-A Cream in the form of A-Ret Gel is used for the topical application in the treatment of acne vulgaris and on skin that has been damaged by excessive exposure to the sun.

Generic Forms and Brand names of Retin-A Cream

A-Ret Gel manufactured by Shalaks Pharmaceuticals Pvt. Ltd., India is an effective treatment for Acne vulgaris, Photoaging and Melasma. Retin-A Cream which has the active ingredient Tretinoin is also sold as Generic Tretinoin Cream, Retino-A Cream, Renova, Aberela, Avita, Airol, Atralin, Stieva-A, Vesanoid and under various other brand names.

A-Ret Gel - Preparations

A-Ret Gel is available as 20 grams tubes of 0.025% or 0.05% or 0.1% strengths .

A-Ret Gel (Generic Retin-A Cream) - Storage Requirements

A-Ret Gel is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

A-Ret Gel (Generic Retin-A Cream) - Dosage

A-Ret Gel should be applied once a day, before bedtime, or as directed by your physician. to the skin where acne lesions appear, using enough to cover the entire affected area lightly. Excessive application of gel results in “pilling” of the gel, which minimizes the likelihood of over application by the patient.
Application may cause a transitory feeling of warmth or slight stinging. In cases where it has been necessary to temporarily discontinue therapy or to reduce the frequency of application, therapy may be resumed or frequency of application increased when the patients become able to tolerate the treatment.
Therapeutic results should be noticed after two to three weeks but more than six weeks of therapy may be required before definite beneficial effects are seen.
Squeeze about a half inch or less of medication onto the fingertip. After you gain some experience with A-Ret Gel you may find you need slightly more or less to do the job. The medication should become invisible almost immediately.
If it is still visible, or if dry flaking occurs from the gel within a minute or so, you are using too much. Cover the affected area lightly with A-Ret Gel (tretinoin) by first dabbing it on your forehead, chin and both cheeks, then spreading it over the entire affected area. Smooth gently into the skin.

A-Ret Gel (Generic Retin-A Cream) - Overdose

If A-Ret Gel is applied excessively, rapid or better results will be not be obtained. However marked redness, peeling, or discomfort may occur. Oral ingestion of Generic Retin-A Cream may lead to the same side effects as those associated with excessive oral intake of Vitamin A.

A-Ret Gel (Generic Retin-A Cream) - Contraindications

A-Ret Gel is contraindicated in patients that have a hypersensitivity to Tretinoin or any inactive ingredient present in A-Ret Gel.

Side Effects Of A-Ret Gel (Generic Retin-A Cream)

The most common side effects of A-Ret Gel which may occur in certain sensitive individuals is that the skin may become excessively red, edematous, blistered, or crusted.
If these effects occur, the medication should either be discontinued until the integrity of the skin is restored, or the medication should be adjusted to a level the patient can tolerate. True contact allergy to topical tretinoin is rarely encountered. Hyper- or hypopigmentation of a Temporary nature has been reported with repeated application of Generic Retin-A Cream.
Some individuals have been reported to have heightened susceptibility to sunlight while under treatment with A-Ret Gel. To date, all adverse effects of A-Ret Gel have been reversible upon discontinuance of therapy

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