Cobese Capsules (Generic Xenical) - Active Ingredient And Chemical structure
The active ingredient contained in Cobese Tablets is Orlistat. Orlistat is a white to off-white crystalline powder. Orlistat is practically insoluble in water, freely soluble in chloroform, and very soluble in methanol and ethanol. Orlistat is a lipase inhibitor which is used for obesity management. It acts by inhibiting the absorption of dietary fats. The structure is shown below
Cobese Capsules (Generic Xenical) - Uses
Generic Xenical in the form of Cobese Capsules is used for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet.
Generic Xenical is also used to reduce the risk for regaining weight after prior weight loss. Generic Xenical is indicated for obese patients with an initial body mass index (BMI) of greater than or equal to 30 kg/m2 or greater than or equal to 27 kg/m2 in the presence of other risk factors (eg, hypertension, diabetes, dyslipidemia).
Generic Forms and Brand names of Xenical
Cobese manufactured by Rambaxy Laboratories Ltd., India is an effective treatment for persons suffering from obesity, in its ability to manage adiposis in adult and adolescent patients. Xenical which has the active ingredient Orlistat is also sold as Alli, Orlimac, Vyfat, Orlistat and under various other brand names.
Cobese Capsules (Generic Xenical) - Preparations
Cobese is available as Capsules of 120 mg. Each capsule of Generic Xenical contains a pellet formulation consisting of 120 mg of the active ingredient, orlistat, as well as the inactive ingredients.
Cobese Capsules (Generic Xenical) - Storage Requirements
Cobese Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.
Cobese Capsules (Generic Xenical) - Dosage
The recommended dose of Generic Xenical is one 120 mg capsule three times a day with each main meal containing fat to be taken during or up to 1 hour after the meal. In case a meal is occasionally missed or contains no fat, the dose of Cobese can be omitted.
Cobese Capsules (Generic Xenical) - Contraindications
Cobese Capsules (Generic Xenical) is contraindicated in patients with chronic malabsorption syndrome or cholestasis, and in patients with known hypersensitivity to Orlistat or to any inactive component of this product.
Generic Xenical (Cobese Capsules) - Overdosage
Single doses of 800 mg of Orlistat (Generic Xenical) and multiple doses of up to 400 mg three times a day for 15 days have been studied in normal weight and obese subjects without significant adverse findings.
Side Effects Of Cobese Capsules (Generic Xenical)
The most common side effects of Cobese Capsules (Generic Xenical) are Oily Spotting, Flatus with Discharge, Fecal Urgency, Fatty/Oily Stool, Oily Evacuation, Increased Defecation and Fecal Incontinence.
