Tuesday, January 3, 2012

A-Ret Gel | Generic Retin-A Cream | Dosage | Uses | Side effects

A-Ret Gel (Generic Retin-A Cream) - Active Ingredient And Chemical structure

The active ingredient contained in A-Ret Gel (Generic Tretinoin Cream) is tretinoin also known as retinoic acid or vitamin A acid in either of two strengths, 0.025% or 0.05% or 0.1% by weight. It is a member of retinoid family of compounds. The structure is shown below

Structure Of Tretinoin


A-Ret Gel ( Generic Retin-A Cream) - Uses

Generic Retin-A Cream in the form of A-Ret Gel is used for the topical application in the treatment of acne vulgaris and on skin that has been damaged by excessive exposure to the sun.


Generic Forms and Brand names of Retin-A Cream

A-Ret Gel manufactured by Shalaks Pharmaceuticals Pvt. Ltd., India is an effective treatment for Acne vulgaris, Photoaging and Melasma. Retin-A Cream which has the active ingredient Tretinoin is also sold as Generic Tretinoin Cream, Retino-A Cream, Renova, Aberela, Avita, Airol, Atralin, Stieva-A, Vesanoid and under various other brand names.


A-Ret Gel - Preparations

A-Ret Gel is available as 20 grams tubes of 0.025% or 0.05% or 0.1% strengths .


A-Ret Gel (Generic Retin-A Cream) - Storage Requirements

A-Ret Gel is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.



A-Ret Gel (Generic Retin-A Cream) - Dosage

A-Ret Gel should be applied once a day, before bedtime, or as directed by your physician. to the skin where acne lesions appear, using enough to cover the entire affected area lightly. Excessive application of gel results in “pilling” of the gel, which minimizes the likelihood of over application by the patient.
Application may cause a transitory feeling of warmth or slight stinging. In cases where it has been necessary to temporarily discontinue therapy or to reduce the frequency of application, therapy may be resumed or frequency of application increased when the patients become able to tolerate the treatment.
Therapeutic results should be noticed after two to three weeks but more than six weeks of therapy may be required before definite beneficial effects are seen.
Squeeze about a half inch or less of medication onto the fingertip. After you gain some experience with A-Ret Gel you may find you need slightly more or less to do the job. The medication should become invisible almost immediately.
If it is still visible, or if dry flaking occurs from the gel within a minute or so, you are using too much. Cover the affected area lightly with A-Ret Gel (tretinoin) by first dabbing it on your forehead, chin and both cheeks, then spreading it over the entire affected area. Smooth gently into the skin.


A-Ret Gel (Generic Retin-A Cream) - Overdose

If A-Ret Gel is applied excessively, rapid or better results will be not be obtained. However marked redness, peeling, or discomfort may occur. Oral ingestion of Generic Retin-A Cream may lead to the same side effects as those associated with excessive oral intake of Vitamin A.


A-Ret Gel (Generic Retin-A Cream) - Contraindications

A-Ret Gel is contraindicated in patients that have a hypersensitivity to Tretinoin or any inactive ingredient present in A-Ret Gel.


Side Effects Of A-Ret Gel (Generic Retin-A Cream)

The most common side effects of A-Ret Gel which may occur in certain sensitive individuals is that the skin may become excessively red, edematous, blistered, or crusted.
If these effects occur, the medication should either be discontinued until the integrity of the skin is restored, or the medication should be adjusted to a level the patient can tolerate. True contact allergy to topical tretinoin is rarely encountered. Hyper- or hypopigmentation of a Temporary nature has been reported with repeated application of Generic Retin-A Cream.
Some individuals have been reported to have heightened susceptibility to sunlight while under treatment with A-Ret Gel. To date, all adverse effects of A-Ret Gel have been reversible upon discontinuance of therapy


Further Information

Prescribing Information