Voveran Tablets | Generic Voltaren | Diclofenac Sodium | Dosage | Uses | Side effects

Voveran Tablets (Generic Voltaren) - Active Ingredient And Chemical structure

Voveran (diclofenac sodium enteric-coated tablets) is a benzene-acetic acid derivative. Voltaren is available as delayed-release (enteric-coated) tablets of 75 mg for oral administration.The active ingredient contained in Voveran is Diclofenac sodium . The structure is shown below

Generic Forms and Brand names of Voltaren (Diclofenac Sodium)

Voveran Tablets manufactured by Novartis, India is is used as an analgesic to treat pain, inflammatory disorders, and dysmenorrhea. Voltaren which has the active ingredient Diclofenac Sodium is also sold as oltaren delo, Voltarol Pain-eze, Voltaren Rapin, Voltaren T, Diclofenac T, Diclofenac-Asteria, Diclofenaco Normon, Morbidic, Voltaflam, Votrex, Cataflam, Abitren, Zipsor and under various other brand names.

Voveran Tablets - Preparations

Voveran is available as tablets of 50 mg and 100 mg .

Voveran Tablets - Storage Requirements

Voveran Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Voveran Tablets (Generic Voltaren) - Uses

Generic Voltaren in the form of Voveran Tablets is used to treat the following indications:
Relief of the signs and symptoms of osteoarthritis
Relief of the signs and symptoms of rheumatoid arthritis
For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis

Voveran Tablets - Contraindications

Voveran Tablets are contraindicated in patients with known hypersensitivity to diclofenac sodium. Voveran should not be given to patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients. Voveran is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.

Voveran Tablets - Dosage

The individual patients dosage should be adjusted after observing the response to initial therapy with Voveran Tablets. For the relief of osteoarthritis, the recommended dosage is 100-150 mg/day in divided doses (50 mg twice a day or thrice a day, or 75 mg twice a day).
For the relief of rheumatoid arthritis, the recommended dosage is 150-200 mg/day in divided doses (50 mg thrice a day or four times a day, or 75 mg twice a day). For the relief of ankylosing spondylitis, the recommended dosage is 100-125 mg/day, administered as 25 mg four times a day, with an extra 25-mg dose at bedtime if necessary.

Side Effects Of Voveran Tablets (Generic Voltaren)

The most common side effects of Voveran Tablets (diclofenac sodium) or other NSAIDs occurring in approximately 1%-10% of patients are Gastrointestinal experiences including: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, gross bleeding/perforation, heartburn, nausea, GI ulcers (gastric/duodenal) and vomiting.Abnormal renal function, anemia, dizziness, edema, elevated liver enzymes, headaches, increased bleeding time, pruritus, rashes and tinnitus. Less common side effects that may occur occasionally include:
Body as a Whole: fever, infection, sepsis
Cardiovascular System: congestive heart failure, hypertension, tachycardia, syncope
Digestive System: dry mouth, esophagitis, gastric/peptic ulcers, gastritis, gastrointestinal bleeding, glossitis, hematemesis, hepatitis, jaundice
Hemic and Lymphatic System: ecchymosis, eosinophilia, leukopenia, melena, purpura, rectal bleeding, stomatitis, thrombocytopenia
Metabolic and Nutritional: weight changes
Nervous System: anxiety, asthenia, confusion, depression, dream abnormalities, drowsiness, insomnia, malaise, nervousness, paresthesia, somnolence, tremors, vertigo
Respiratory System: asthma, dyspnea
Skin and Appendages: alopecia, photosensitivity, sweating increased
Special Senses: blurred vision
Urogenital System: cystitis, dysuria, hematuria, interstitial nephritis, oliguria/polyuria, proteinuria, renal failure
Other adverse reactions, which occur rarely are:
Body as a Whole: anaphylactic reactions, appetite changes, death
Cardiovascular System: arrhythmia, hypotension, myocardial infarction, palpitations, vasculitis
Digestive System: colitis, eructation, fulminant hepatitis with and without jaundice, liver failure, liver necrosis, pancreatitis
Hemic and Lymphatic System: agranulocytosis, hemolytic anemia, aplastic anemia, lymphadenopathy, pancytopenia
Metabolic and Nutritional: hyperglycemia
Nervous System: convulsions, coma, hallucinations, meningitis
Respiratory System: respiratory depression, pneumonia
Skin and Appendages: angioedema, toxic epidermal necrolysis, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, urticaria
Special Senses: conjunctivitis, hearing impairment

Symptoms And Treatment Of Voveran Tablets (Generic Voltaren) Overdose

Symptoms following acute Voveran Tablets or other NSAID overdoses are usually limited to lethargy, drowsiness, nausea,vomiting, and epigastric pain, which are generally reversible with supportive care. Gastrointestinal bleeding can occur. Hypertension, acute renal failure, respiratory depression and coma may occur, but are rare. Anaphylactoid reactions have been reported with therapeutic ingestion of NSAIDs, and may occur following an overdose.
Patients should be managed by symptomatic and supportive care following a NSAID overdose. There are no specific antidotes. Emesis and/or activated charcoal (60 to 100 g in adults, 1 to 2 g/kg in children) and/or osmotic cathartic may be indicated in patients seen within 4 hours of ingestion with symptoms or following a large overdose (5 to 10 times the usual dose).

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Crocin Tablets | Generic Paracetamol | Acetaminophen | Dosage | Uses | Side effects

Crocin Tablets (Generic Paracetamol) - Active Ingredient And Chemical structure

The active ingredient contained in Crocin Tablets is Paracetamol (Acetaminophen). Paracetamol (Acetaminophen) is a nonopiate, non-salicylate analgesic and antipyretic substance. Paracetamol is a white, odorless, crystalline powder, possessing a slightly bitter taste.The structure is shown below

Generic Forms and Brand names of Paracetamol

Crocin manufactured by GlaxoSmithKline, India is an effective treatment to reduce fever, for the relief of headaches as well as other minor aches and pains. Paracetamol (Acetaminophen) which has is also sold as Paracip, Fepanil, Panadol, Acetaminophen, Acamol, Acephen, Aceta, Actamin, Actimin, Anacin-3, Apacet, Atasol, Banesin, Ben-u-ron, Biogesic, Dafalgan, Dapa, Dolo, Datril, Efferalgan, DayQuil, Depon, Doliprane, Feverall, Fibi, Genapap, Genebs, Lekadol, LemSip, Liquiprin, Lupocet, Milidon, Neopap, Ny-Quil, Oraphen-PD, Ofirmev, Panado, Panadol, Panadrex, Panamax, Paracet, Parol, Panodil, Paratabs, Paralen, Phenaphen, Plicet, PyongSu Cetamol, Redutemp, Snaplets-FR, Suppap, Tactinal, Tachipirina, Tamen, Tapanol, Tempra, Uphamol, Valorin, Vitapap, Xcel and under various other brand names.

Crocin (Acetaminophen) - Uses

Acetaminophen is available as Generic Paracetamol Tablets is used for relief of persistent pain associated with osteoarthritis and muscle aches and pains such as backache. It is also used for reducing fever. Crocin also provides effective, temporary relief of pain and discomfort associated with headache, tension headache, period pain, toothache and pain after dental procedures, cold and flu.

Crocin Tablets (Paracetamol) - Preparations

Crocin (Acetaminophen) is available as tablets of 500 mg .

Crocin (Acetaminophen) - Storage Requirements

Crocin (Acetaminophen) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Crocin (Paracetamol) - Dosage

The recommended dosage for adults and children over 12 years is Two tablets of 500 mg swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24hours). The tablets must not be crushed.

Crocin (Paracetamol) - Contraindications

Crocin is contraindicated in persons that have a hypersensitivity to paracetamol or to any of the inactive ingredients. Crocin should be administered with caution to patients with hepatic or renal dysfunction. It is not recommended for children under 12 years of age.

Crocin (Paracetamol) - Overdose

Paracetamol overdose may cause hepatic failure. Immediate medical management is required in the event of overdose, even if symptoms of overdose are not present. Prompt treatment is essential even when there are no obvious symptoms.
In cases of over dosage, prompt administration of activated charcoal 50 g in 150 mL of water and 150 mL sorbitol 50% solution by mouth may reduce absorption. It is recommended that intravenous fluids such as Normal Saline be given concurrently. Gastric lavage is indicated if the patient is unwilling or unable to drink an activated charcoal/sorbitol mixture.

Side Effects Of Crocin (Paracetamol)

Reports of side effects are rare. Dyspepsia, nausea, allergic and haematological reactions have been reported but a causal relationship to the administration of paracetamol has been neither confirmed nor refuted.

Duprost Capsules | Generic Avodart | Dutasteride | Dosage | Uses | Side effects

Duprost Capsules (Generic Avodart) - Active Ingredient And Chemical structure

Dutasteride is a white to pale yellow powder with a melting point of 242°C to 250°C . It is soluble in ethanol (44 mg/mL), methanol (64 mg/mL), and polyethylene glycol 400 (3 mg/mL), but it is insoluble in water. Each Duprost Soft Gelatin Capsule, administered orally, contains 0.5 mg of dutasteride. The structure is shown below

Generic Forms and Brand names of Avodart (Dutasteride)

Duprost Capsules manufactured by Cipla Ltd. , India is an effective for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Avodart which has the active ingredient Dutasteride is also sold as Avidart, Avolve, Duagen, Dutagen, Dutas and under various other brand names.

Duprost Capsules (Generic Avodart) - Preparations

Duprost is available as Capsules of 0.5 mg .

Duprost Capsules (Generic Avodart) - Storage Requirements

Duprost Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Duprost Capsules (Generic Avodart) - Uses

Avodart in the form of Duprost Capsules a 5 alpha-reductase inhibitor indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to:
1) Improve symptoms
2) Reduce the risk of acute urinary retention, and
3) Reduce the risk of the need for BPH-related surgery.
Duprost Capsules in combination with the alpha adrenergic antagonist, tamsulosin, is indicated for the treatment of symptomatic BPH in men with an enlarged prostate.

Duprost Capsules (Generic Avodart) - Dosage

The recommended dosage for Duprost Monotherapy is 0.5 mg once daily. In Combination with tamsulosin: 0.5 mg once daily and tamsulosin 0.4 mg once daily. The capsules have to be swallowed whole. Capsules may be taken with or without food.

Duprost Capsules (Generic Avodart) - Contraindications

Duprost Capsules are contraindicated in the following cases:
Pregnancy and women of childbearing potential.
Pediatric patients.
Patients with previously demonstrated, clinically significant hypersensitivity (e.g., serious skin reactions, angioedema) to Duprost or other 5 alpha-reductase inhibitors.

Side Effects Of Duprost Capsules (Generic Avodart)

The most common side effects of are are impotence, decreased libido, ejaculation disorders, and breast disorders.

Further Information

Prescribing Information