Tuesday, September 27, 2011

Crocin Tablets | Generic Paracetamol | Acetaminophen | Dosage | Uses | Side effects

Crocin Tablets (Generic Paracetamol) - Active Ingredient And Chemical structure

The active ingredient contained in Crocin Tablets is Paracetamol (Acetaminophen). Paracetamol (Acetaminophen) is a nonopiate, non-salicylate analgesic and antipyretic substance. Paracetamol is a white, odorless, crystalline powder, possessing a slightly bitter taste.The structure is shown below
Structure Of Paracetamol


Generic Forms and Brand names of Paracetamol

Crocin manufactured by GlaxoSmithKline, India is an effective treatment to reduce fever, for the relief of headaches as well as other minor aches and pains. Paracetamol (Acetaminophen) which has is also sold as Paracip, Fepanil, Panadol, Acetaminophen, Acamol, Acephen, Aceta, Actamin, Actimin, Anacin-3, Apacet, Atasol, Banesin, Ben-u-ron, Biogesic, Dafalgan, Dapa, Dolo, Datril, Efferalgan, DayQuil, Depon, Doliprane, Feverall, Fibi, Genapap, Genebs, Lekadol, LemSip, Liquiprin, Lupocet, Milidon, Neopap, Ny-Quil, Oraphen-PD, Ofirmev, Panado, Panadol, Panadrex, Panamax, Paracet, Parol, Panodil, Paratabs, Paralen, Phenaphen, Plicet, PyongSu Cetamol, Redutemp, Snaplets-FR, Suppap, Tactinal, Tachipirina, Tamen, Tapanol, Tempra, Uphamol, Valorin, Vitapap, Xcel and under various other brand names.


Crocin (Acetaminophen) - Uses

Acetaminophen is available as Generic Paracetamol Tablets is used for relief of persistent pain associated with osteoarthritis and muscle aches and pains such as backache. It is also used for reducing fever. Crocin also provides effective, temporary relief of pain and discomfort associated with headache, tension headache, period pain, toothache and pain after dental procedures, cold and flu.


Crocin Tablets (Paracetamol) - Preparations

Crocin (Acetaminophen) is available as tablets of 500 mg .


Crocin (Acetaminophen) - Storage Requirements

Crocin (Acetaminophen) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.


Crocin (Paracetamol) - Dosage

The recommended dosage for adults and children over 12 years is Two tablets of 500 mg swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24hours). The tablets must not be crushed.


Crocin (Paracetamol) - Contraindications

Crocin is contraindicated in persons that have a hypersensitivity to paracetamol or to any of the inactive ingredients. Crocin should be administered with caution to patients with hepatic or renal dysfunction. It is not recommended for children under 12 years of age.


Crocin (Paracetamol) - Overdose

Paracetamol overdose may cause hepatic failure. Immediate medical management is required in the event of overdose, even if symptoms of overdose are not present. Prompt treatment is essential even when there are no obvious symptoms.
In cases of over dosage, prompt administration of activated charcoal 50 g in 150 mL of water and 150 mL sorbitol 50% solution by mouth may reduce absorption. It is recommended that intravenous fluids such as Normal Saline be given concurrently. Gastric lavage is indicated if the patient is unwilling or unable to drink an activated charcoal/sorbitol mixture.


Side Effects Of Crocin (Paracetamol)

Reports of side effects are rare. Dyspepsia, nausea, allergic and haematological reactions have been reported but a causal relationship to the administration of paracetamol has been neither confirmed nor refuted.