Virovir Tablets | Generic Famvir | Famciclovir | Dosage | Uses | Side effects

Virovir Tablets (Generic Famvir) - Active Ingredient And Chemical structure

The active ingredient contained in Virovir Tablets is Famciclovir. Famciclovir is a white to pale yellow solid. It is freely soluble in acetone and methanol, and sparingly soluble in ethanol and isopropanol. The structure is shown below

Generic Forms and Brand names of Famvir

Virovir Tablets manufactured by FDC Ltd. , India is an effective treatment for Herpes labialis (cold sores), Genital herpes and Herpes zoster (shingles) in adult patients. Famvir which has the active ingredient Famciclovir is also sold under various other brand names.

Virovir Tablets - Preparations

Virovir is available as tablets of 250 mg .

Virovir Tablets - Storage Requirements

Virovir Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Generic Famvir (Famciclovir) - Uses

Generic Famvir in the form of Virovir Tablets is used to treat Herpes labialis (cold sores) Genital herpes and Herpes zoster (shingles) in adult patients.

Warnings and Precautions when using Virovir Tablets (Generic Famvir)

Acute renal failure cases have been reported in patients with underlying renal disease who have received inappropriately high doses of Virovir for their level of renal function. Dosage reduction is recommended when administering Virovir to patients with renal impairment.

Virovir Tablets (Generic Famvir) - Contraindications

Virovir Tablets is contraindicated in patients with known hypersensitivity to Famciclovir, its inactive components, or Denavir.

Virovir Tablets (Generic Famvir) - Dosage

Below are the recommended Dosage recommendation in Immunocompetent Adult Patients
Herpes labialis (cold sores):
The recommended dosage of FAMVIR for the treatment of recurrent herpes labialis is 1500 mg as a single dose. Therapy should be initiated at the first sign or symptom of herpes labialis (e.g., tingling, itching, burning, pain, or lesion).
Genital herpes:
Recurrent episodes: The recommended dosage of FAMVIR for the treatment of recurrent episodes of genital herpes is 1000 mg twice daily for 1 day. Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion).
Suppressive therapy: The recommended dosage of FAMVIR for chronic suppressive therapy of recurrent episodes of genital herpes is 250 mg twice daily.
Herpes zoster (shingles):
The recommended dosage of FAMVIR for the treatment of herpes zoster is 500 mg every 8 hours for 7 days. Therapy should be initiated as soon as herpes zoster is diagnosed.

Side Effects Of Virovir Tablets (Famciclovir)

The most common side effects of Virovir Tablets (Famciclovir) are headache and nausea. Less common side effects that may occur are Paresthesia, Migraine, Diarrhea, Vomiting, Flatulence, Abdominal Pain, Fatigue, Pruritus, Rash and Dysmenorrhea.

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Zovirax Tablets | Acyclovir | Dosage | Uses | Side effects

Zovirax Tablets (Acyclovir) - Active Ingredient And Chemical structure

The active ingredient contained in Zovirax Tablets is Acyclovir . Acyclovir is a white, crystalline powder with a molecular weight of 225. The maximum solubility in water at 37 °C is 2.5 mg/mL.The structure is shown below

Generic Forms and Brand names of Zovirax

Zovirax manufactured by GlaxoSmithKline (GSK), India is an effective treatment for chickenpox (varicella) or shingles (herpes zoster) and treating or suppressing genital herpes infections. Zovirax which has the active ingredient Acyclovir is also sold as Cyclovir, Herpex, Acivirax, Zovir, Acyclovir, Aciclovir, Zelitrex, Valtrex, Acyclovir and under various other brand names.

Zovirax Tablets (Acyclovir) - Uses

Acyclovir in the form of Zovirax Tablets is used to treat Herpes Zoster Infections (shingles), for the treatment of initial episodes and the management of recurrent episodes of genital herpes, treatment of chickenpox (varicella).

Zovirax Tablets - Contraindications

Zovirax is contraindicated in patients that have a hypersensitivity to acyclovir or valacyclovir. Dosage adjustment is recommended when administering Zovirax tablets to patients with renal impairment.
Caution should also be exercised when administering Zovirax to patients receiving potentially nephrotoxic agents since this may increase the risk of renal dysfunction and/or the risk of reversible central nervous system symptoms

Zovirax Tablets - Preparations

Zovirax Tablets is available as tablets of 200 mg, 400 mg and 800 mg. Each 200 mg tablet of Zovirax contains 200 mg of acyclovir and the inactive ingredients magnesium stearate, microcrystalline cellulose, povidone, and sodium starch glycolate.

Zovirax Tablets - Storage Requirements

Zovirax Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Zovirax Tablets - Symptoms Of Overdosage

The Adverse effects due to that have been reported in association with overdosage due to ingestion of up to 100 capsules (20 g)include agitation, coma, seizures, and lethargy. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored.

Zovirax Tablets - Dosage

Acute Treatment of Herpes Zoster:
800 mg every 4 hours orally, 5 times daily for 7 to 10 days.
Genital Herpes:
Treatment of Initial Genital Herpes:
200 mg every 4 hours, 5 times daily for 10 days.
Chronic Suppressive Therapy for Recurrent Disease:
400 mg 2 times daily for up to 12 months, followed by re-evaluation. Alternative regimens have included doses ranging from 200 mg 3 times daily to 200 mg 5 times daily. The frequency and severity of episodes of untreated genital herpes may change over time. After 1 year of therapy, the frequency and severity of the patient’s genital herpes infection should be reevaluated to assess the need for continuation of therapy with Zovirax.
Intermittent Therapy:
200 mg every 4 hours, 5 times daily for 5 days. Therapy should be initiated at the earliest sign or symptom (prodrome) of recurrence.
Treatment of Chickenpox:
Children (2 years of age and older):
20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. Children over 40 kg should receive the adult dose for chickenpox.
Adults and Children over 40 kg:
800 mg 4 times daily for 5 days. Intravenous Zovirax is indicated for the treatment of varicella-zoster infections in immunocompromised patients. When therapy is indicated, it should be initiated at the earliest sign or symptom of chickenpox.

Side Effects Of Zovirax Tablets

The most common side effects of Zovirax Tablets are were nausea,vomiting, diarrhea, headache and malaise.

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Azee Tablets | Generic Zithromax | Azithromycin | Dosage | Uses | Side effects

Azee Tablets (Generic Zithromax) - Active Ingredient And Chemical structure

The active ingredient contained in Azee is Azithromycin an azalide, a subclass of macrolide antibiotics, for oral administration. The structure is shown below

Generic Zithromax (Azithromycin) - Uses

Generic Zithromax in the form of Azee Tablets is used to treat Upper respiratory tract infections (including ear, nose and throat infections), Lower respiratory tract infections, Genitourinary tract infections (including sexually transmitted diseases), Skin and skin structure infections, Prophylaxis and treatment of malaria, Treatment of acne, Treatment of chlamydial conjunctivitis.

Azee Tablets (Generic Zithromax) - Preparations

Azee is available as tablets of 250 mg, 500 mg and 1000 mg. Each tablet contains Azithromycin Dihydrate equivalent to Azithromycin (anhydrous) USP 250 mg, 500 mg and 1000 mg respectively.

Generic Forms and Brand names of Zithromax (Azithromycin)

Azee manufactured by Cipla Ltd., India is used to treat or prevent bacterial infections like upper and lower genitourinary tract infections, respiratory tract infections(including ear, nose and throat infections), skin and skin structure infections. Zithromax which has the active ingredient Azithromycin is also sold as Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax and under various other brand names.

Azee Tablets (Generic Zithromax) - Storage Requirements

Azee Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Azee Tablets (Generic Zithromax) - Dosage

Below is given the recommended adult dosage to treat various indications:
Mild to moderate lower respiratory tract infections, upper respiratory tract infections and uncomplicated skin and soft tissue infections:
Adults Dosage:500 mg as a single dose on the first day followed by 250 mg once daily on days 2 to 5 for a total dose of 1.5 g or 500 mg once daily for 3 days.
Sexually transmitted diseases:
– Gonorrhoea: 2 gm as a stat dose
– Chancroid: 1 gm as a stat dose
– Non-gonococcal urethritis and cervicitis due to C. trachomatis –1 gm as a stat dose
– Syphilis: 1 gm o.d. for 5 days or 500 mg o.d. for 10 days.
Malaria:
– Prophylaxis: 500 mg on first day followed by 250 mg/day for 7 days.
– Treatment: 1000-1500 mg once daily for 3 days with usual doses of chloroquine.
Acne:
250-500 mg on 3 consecutive days in a week for 12 weeks.

Azee Tablets - Contraindications

Azee is contraindicated in patients which are allergic to azithromycin, erythromycin, or any other macrolide or ketolide antibiotics.

Side Effects Of Azee Tablets (Generic Zithromax)

The most common side effects of Azee tablets are nausea, vomiting, diarrhea, or abdominal pain. Rarely occuring side effects are Palpitations, chest pain, Dyspepsia, flatulence, vomiting, melena and cholestatic jaundice, Monilia, vaginitis and nephritis, Dizziness, headache, vertigo and somnolence, Fatigue, Rash, pruritus, photosensitivity and angioedema.

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Neotrexate Tablets | Generic Rheumatrex | Methotrexate | Dosage | Uses | Side effects

Neotrexate Tablets (Generic Rheumatrex) - Active Ingredient And Chemical structure

The active ingredient contained in Neotrexate Tablets is Methotrexate. Neotrexate is an antimetabolite used in the treatment of certain neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis. The structure is shown below

Neotrexate Tablets (Generic Rheumatrex) - Uses

Methotrexate in the form of Neotrexate Tablets is used to treat cancer, autoimmune diseases, ectopic pregnancy, Eczema, Lymphoma and Trophoblastic Disease.

Generic Forms and Brand names of Rheumatrex

Neotrexate Tablets manufactured by GlaxoSmithKline, India is an effective treatment for neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis. Rheumatrex which has the active ingredient Methotrexate is also sold as Trexall, MTX, Amethopterin, Generic Methotrexate and under various other brand names.

Neotrexate Tablets (Generic Rheumatrex) - Preparations

Neotrexate (Methotrexate) is available as tablets of 2.5 mg.

Neotrexate Tablets (Generic Rheumatrex) - Storage Requirements

Neotrexate Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Neotrexate Tablets (Generic Rheumatrex)- Dosage

Choriocarcinoma and similar trophoblastic diseases:
Neotrexate Tablets (Methotrexate) is administered orally in doses of 15 to 30 mg daily for a five-day course. Such courses are usually repeated for 3 to 5 times as required, with rest periods of one or more weeks interposed between courses, until any manifesting toxic symptoms subside.
Psoriasis, Rheumatoid Arthritis, and Juvenile Rheumatoid Arthritis
The Recommended Starting Dosage schedules for Neotrexate Tablets (Generic Rheumatrex) to treat Adult Rheumatoid Arthritisis is
1. Single oral doses of 7.5 mg once weekly.
2. Divided oral dosages of 2.5 mg at 12 hour intervals for 3 doses given as a course once weekly.
The Recommended Starting Dosage schedules for Polyarticular-Course Juvenile Rheumatoid Arthritis:
The recommended starting dose is 10 mg/m2 given once weekly.

Neotrexate Tablets (Generic RMethotrexate) - Contraindications

Neotrexate Tablets (Methotrexate) is contraindicated in pregnant women with psoriasis or rheumatoid arthritis and should be used in the treatment of neoplastic diseases only when the potential benefit outweighs the risk to the fetus.
Pregnancy should be avoided if either partner is receiving methotrexate; during and for a minimum of three months after therapy for male patients, and during and for at least one ovulatory cycle after therapy for female patients. Patients with psoriasis or rheumatoid arthritis with alcoholism, alcoholic liver disease or other chronic liver disease should not receive methotrexate. Patients with psoriasis or rheumatoid arthritis who have overt or laboratory evidence of immunodeficiency syndromes should not receive methotrexate.
Patients with psoriasis or rheumatoid arthritis who have preexisting blood dyscrasias, such as bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anemia, should not receive methotrexate.
Since Neotrexate has the potential for serious adverse reactions from methotrexate in breast fed infants, it is contraindicated in nursing mothers.
Patients with a known hypersensitivity to methotrexate or any inactive ingredient present in Neotrexate should not be administered the drug.

Side Effects Of Neotrexate Tablets (Generic Rheumatrex)

The most frequently occurring side effects of Neotrexate Tablets include ulcerative stomatitis, leukopenia, nausea, and abdominal distress. Other frequently reported side effects are malaise, undue fatigue, chills and fever, dizziness and decreased resistance to infection.

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Fertomid Tablets | Generic Clomid | Clomiphene Citrate | Dosage | Uses | Side effects

Fertomid Tablets (Generic Clomid) - Active Ingredient And Chemical structure

The active ingredient contained in Fertomid Tablets is Clomiphene Citrate. Clomiphene citrate is a white to pale yellow crystalline powder which is essentially odorless. It is freely soluble in methanol; soluble in ethanol; slightly soluble in acetone, water, and chloroform. The structure is shown below

Generic Forms and Brand names of Clomid (Clomiphene Citrate)

Fertomid Tablets manufactured by Cipla Ltd., India is an effective treatment for patients with persistent ovulatory dysfunction. Clomid which has the active ingredient Clomiphene Citrate is also sold as Serophene, Milophene, Clomifert and under various other brand names.

Clomiphene Citrate - Uses

Clomiphene Citrate in the form of Fertomid Tablets is used for induction of ovulation in patients with persistent ovulatory dysfunction who desire pregnancy. Fertomid can be used to make an irregularly ovulating woman ovulate regularly.
Fertomid is useful in the treatment of oligomenorrhoea, dysfunctional uterine bleeding, amenorrhoea, post pill menorrhoea, Stein Leventhal syndrome (polycystic ovarian diseases), and Chiari Frommel syndrome.

Fertomid Tablets - Preparations

Fertomid (Generic Clomid) is available as tablets of 25 mg and 50 mg.

Fertomid Tablets (Clomiphene Citrate) - Storage Requirements

Fertomid Tablets are to be stored at room temperature (15°C to 30°C). Store Clomiphene away from heat, moisture, and light.

Contraindications Of Fertomid Tablets

Fertomid Tablets (Generic Clomid) are contraindicated in patients with a known hypersensitivity or allergy to clomiphene citrate or to any of its inactive ingredients.

Fertomid Tablets - Dosage

For the treatment of Female infertility One tablet of Fertomid 50 mg is to be administered daily for five days starting on the 5th day of the menstrual cycle. If ovulation does not appear to have occurred, a second course of two tablets of Fertomid 50 mg daily (in a single dose) for five days should be administered starting from the fifth day of the next cycle.

Side Effects Of Fertomid Tablets

The most common side effects of Fertomid Tablets (Clomiphene Citrate) are Ovarian Enlargement, Vasomotor Flushes, Abdominal-Pelvic Discomfort/Distention/Bloating, Nausea and Vomiting, Breast Discomfort, Blurred vision, lights, floaters, waves, unspecified visual complaints, photophobia, diplopia, scotomata, phosphenes, Headache, Abnormal Uterine Bleeding, Intermenstrual spotting, menorrhagia. Less common side effects that may occur are Acute abdomen, appetite increase, constipation, dermatitis or rash, depression, diarrhoea, dizziness, fatigue, hair loss/dry hair, increased urinary frequency/volume, insomnia, light-headedness, nervous tension, vaginal dryness, vertigo, weight gain/loss.

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Ciplox Tablets | Generic Cipro | Ciprofloxacin Hydrochloride | Dosage | Uses | Side effects

Ciplox Tablets (Generic Cipro) - Active Ingredient And Chemical structure

Ciplox (Generic Cipro) is a synthetic broad spectrum antimicrobial agents for oral administration. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8. The active ingredient contained in Ciplox Tablets is Ciprofloxacin Hydrochloride. The structure is shown below

Generic Forms and Brand names of Cipro (Ciprofloxacin Hydrochloride)

Ciplox manufactured by Cipla Ltd., India is an effective treatment of certain infections caused by susceptible bacteria. Cipro which has the active ingredient Ciprofloxacin Hydrochloride is also sold as Ciloxan, Proquin Baycip, Ciloxan, Ciflox, Cipro XL, Ciproxin, Prociflor, Proquin and under various other brand names.

Generic Cipro (Ciprofloxacin Hydrochloride) - Uses

Ciprofloxacin Hydrochloride in the form of Ciplox Tablets is used to treat the below mentioned indications in Adult Patients:
Urinary Tract Infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, methicillin-susceptible Staphylococcus epidermidis, Staphylococcus saprophyticus, or Enterococcus faecalis. Acute Uncomplicated Cystitis in females caused by Escherichia coli or Staphylococcus saprophyticus.
Chronic Bacterial Prostatitis caused by Escherichia coli or Proteus mirabilis.
Lower Respiratory Tract Infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Pseudomonas aeruginosa, Haemophilus influenzae, Haemophilus parainfluenzae, or penicillin-susceptible Streptococcus pneumoniae. Also, Moraxella catarrhalis for the treatment of acute exacerbations of chronic bronchitis.
Skin and Skin Structure Infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Morganella morganii, Citrobacter freundii, Pseudomonas aeruginosa, methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, or Streptococcus pyogenes.
Bone and Joint Infections caused by Enterobacter cloacae, Serratia marcescens, or Pseudomonas aeruginosa.
Complicated Intra-Abdominal Infections (used in combination with metronidazole) caused by Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, or Bacteroides fragilis.
Infectious Diarrhea caused by Escherichia coli (enterotoxigenic strains), Campylobacter jejuni, Shigella boydii, Shigella dysenteriae, Shigella flexneri or Shigella sonnei when antibacterial therapy is indicated.
Typhoid Fever (Enteric Fever) caused by Salmonella typhi.
Uncomplicated cervical and urethral gonorrhea due to Neisseria gonorrhoeae.

Ciplox Tablets (Generic Cipro) - Preparations

Ciplox is available as tablets of 100 mg, 250 mg, 500 mg and 750 mg .

Ciplox Tablets - Storage Requirements

Ciplox Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.

Ciplox Tablets (Generic Cipro) - Dosage

Ciplox tablets should be swallowed whole with adequate amount of liquid.
Ciplox tablets can be taken with or without meals. Antacids should not be taken concomitantly or within two hours of dosing. Below are the recommended dosages for adults for the specific indications.
Respiratory tract, bone and joint infections
Mild/moderate 500 mg twice daily/or 1000 mg once daily
Severe/complicated 750 mg twice daily
Urinary tract infections
Acute uncomplicated 500 mg od for 3 days
Mild/moderate 250 mg twice daily / 500 mg once daily
Severe/complicated 500 mg twice daily/or 1000 mg once daily
Infectious diarrhoea
Mild/moderate/severe 500 mg twice daily/or 1000 mg once daily
Gonorrhoea 250 mg single dose
Non-gonococcal urethritis 750 mg twice daily
Chancroid 500 mg twice daily/1000 mg once daily
Other infections 500-750 mg twice daily
Chronic Bacterial prostatitis: 1000 mg o.d. for 28 days

Ciplox Tablets (Generic Cipro) - Contraindications

Ciplox is contraindicated in persons with a hypersensitivity to ciprofloxacin, any member of the quinolone class of antimicrobial agents, or any of the product inactive components.

Side Effects Of Ciplox Tablets (Generic Cipro)

Ciplox (Ciprofloxacin)is generally well tolerated. The most common side effects of are Diarrhoea, vomiting, abdominal pain, headache, restlessness and rash, have been reported. Other side effects which have been reported very rarely include myalgia, tendonitis/rupture, exacerbation of myasthenia gravis and increases in serum transaminase levels.

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