Thursday, December 29, 2011

Flutivate Cream | Generic Cutivate | Dosage | Uses | Side effects

Flutivate Cream (Generic Cutivate) - Active Ingredient And Chemical structure

The active ingredient contained in Flutivate Cream is Fluticasone Propionate. Fluticasone propionate is a white powder with a molecular weight of 500.6, It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.The structure is shown below

Structure Of Fluticasone Propionate


Flutivate Cream (Generic Cutivate) - Uses

Generic Cutivate in the form of Flutivate Cream is used to treat inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.



Generic Forms and Brand names of Cutivate

Flutivate Cream manufactured by GlaxoSmithKline, India is an effective treatment for eczema, psoriasis, allergies and rash. Cutivate which has the active ingredient Fluticasone Propionate is also sold under various other brand names.



Flutivate Cream (Generic Cutivate) - Preparations

Flutivate Cream is available as tubes of 20 g tubes containing Fluticasone Propionate IP 0.005% w/w.



Flutivate Cream (Generic Cutivate) - Contraindications

Flutivate Cream (Fluticasone propionate cream, 0.05%) is contraindicated in patients with a hypersensitivity to Fluticasone propionate or any of the inactive ingredients present in Flutivate cream. The preparation also contraindicated in the treatment of rosacea, acne vulgaris, perioral dermatitis, primary cutaneous viral infections (i.e., herpes simplex, chickenpox), perianal and genital pruritus, primarily infected skin lesions caused by infection with fungi or bacteria and dermatoses in children, including dermatitis and diaper rash.



Flutivate Cream (Generic Cutivate) - Storage Requirements

Flutivate Cream is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.



Flutivate Cream (Generic Cutivate) - Overdose

In case of Overdosage , treatment should be discontinued if the symptoms of hypercorticism appear. Topically applied fluticasone propionate cream, 0.05% can be absorbed in sufficient amounts to produce systemic effects.



Flutivate Cream (Generic Cutivate) - Dosage

The dosage of Flutivate cream to treat various indications is given below.
Eczema: Apply a thin film of Flutivate Cream (fluticasone propionate) Cream to the affected skin areas once or twice daily. Rub in gently.
Other Corticosteroid Responsive Dermatoses: Apply a thin film of Flutivate Cream 0.05% to the affected skin areas twice daily . Rub in gently.



Side Effects Of Flutivate Cream (Generic Cutivate)

The total occurence of side effects associated with the use of Flutivate Cream (fluticasone propionate cream, 0.05% ) was approximately 4%. These adverse reactions were mild and self-limiting. For fluticasone propionate cream 0.05%, these reactions consisted primarily of pruritus, dryness, numbness of fingers, and burning.