Duprost Capsules (Generic Avodart) - Active Ingredient And Chemical structure
Dutasteride is a white to pale yellow powder with a melting point of 242°C to 250°C . It is soluble in ethanol (44 mg/mL), methanol (64 mg/mL), and polyethylene glycol 400 (3 mg/mL), but it is insoluble in water. Each Duprost Soft Gelatin Capsule, administered orally, contains 0.5 mg of dutasteride. The structure is shown below
Generic Forms and Brand names of Avodart (Dutasteride)
Duprost Capsules manufactured by Cipla Ltd. , India is an effective for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Avodart which has the active ingredient Dutasteride is also sold as Avidart, Avolve, Duagen, Dutagen, Dutas and under various other brand names.
Duprost Capsules (Generic Avodart) - Preparations
Duprost is available as Capsules of 0.5 mg .
Duprost Capsules (Generic Avodart) - Storage Requirements
Duprost Capsules are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light.
Duprost Capsules (Generic Avodart) - Uses
Avodart in the form of Duprost Capsules a 5 alpha-reductase inhibitor indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to:
1) Improve symptoms
2) Reduce the risk of acute urinary retention, and
3) Reduce the risk of the need for BPH-related surgery.
Duprost Capsules in combination with the alpha adrenergic antagonist, tamsulosin, is indicated for the treatment of symptomatic BPH in men with an enlarged prostate.
Duprost Capsules (Generic Avodart) - Dosage
The recommended dosage for Duprost Monotherapy is 0.5 mg once daily. In Combination with tamsulosin: 0.5 mg once daily and tamsulosin 0.4 mg once daily. The capsules have to be swallowed whole. Capsules may be taken with or without food.
Duprost Capsules (Generic Avodart) - Contraindications
Duprost Capsules are contraindicated in the following cases:
Pregnancy and women of childbearing potential.
Pediatric patients.
Patients with previously demonstrated, clinically significant hypersensitivity (e.g., serious skin reactions, angioedema) to Duprost or other 5 alpha-reductase inhibitors.
Side Effects Of Duprost Capsules (Generic Avodart)
The most common side effects of are are impotence, decreased libido, ejaculation disorders, and breast disorders.
