Friday, September 2, 2011

Nexpro Tablets | Generic Nexium | Esomeprazole | Dosage | Uses | Side effects

Nexpro Tablets (Generic Nexium) - Active Ingredient And Chemical structure

The active ingredient contained in Nexpro Tablets is Esomeprazole Magnesium, a compound that inhibits gastric acid secretion. Esomeprazole Magnesium is a white to slightly colored crystalline powder which is slightly soluble in water. The structure is shown below

Structure Of Esomeprazole


Generic Nexium (Esomeprazole Magnesium) - Uses

Generic Nexium (Esomeprazole Magnesium) in the form of Nexpro Tablets is used in the treatment of Gastroesophageal Reflux Disease (GERD), Risk Reduction of NSAID-Associated Gastric Ulcer, H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence, Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome.


Generic Forms and Brand names of Nexium (Esomeprazole Magnesium)

Nexpro Tablets manufactured by Torrent Pharmaceuticals Ltd., India is an effective treatment for symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. Nexium which has the active ingredient Esomeprazole Magnesium is also sold as Sompraz, Esopral, Lucen, Axagon, Nexiam or Zoleri and under various other brand names.


Nexpro Tablets (Generic Nexium) - Preparations

Nexpro Tablets (Esomeprazole Magnesium) are available as tablets of 20 mg and 40 mg .


Nexpro Tablets - Storage Requirements

Nexpro Tablets (Esomeprazole Magnesium) are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.


Nexpro Tablets (Esomeprazole Magnesium) - Dosage

The recommended dosage of Nexpro tablets for various indications is given below:

Indication Dose Frequency
Gastroesophageal Reflux Disease (GERD)
Healing of Erosive Esophagitis20 mg or 40 mgOnce Daily for 4 to 8 Weeks
Maintenance of Healing of Erosive Esophagitis20 mg Once Daily
Symptomatic Gastroesophageal Reflux Disease20 mgOnce Daily for 4 Weeks
Risk Reduction of NSAID Associated Gastric Ulcer 20 mg or 40 mgOnce Daily for up to 6 months
H.pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence
Triple Therapy:
Nexpro40 mgOnce Daily for 10 Days
Amoxicillin1000 mgTwice Daily for 10 Days
Clarithromycin500 mgTwice Daily for 10 Days
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome40 mgTwice Daily

Nexpro Tablets (Generic Nexium) - Contraindications

Nexpro is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles.


Side Effects Of Nexpro Tablets (Generic Nexium)

The most common side effects of are Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth.


Further Information

Prescribing Information