Flonida Cream (Generic Carac) - Active Ingredient And Chemical structure
Flonida (Fluorouracil) 1% and 5% Topical Cream is an antineoplastic/antimetabolite medication for dermatological use. The active ingredient contained in Flonida Cream is Fluorouracil. It is sparingly soluble in water and slightly soluble in alcohol. The structure is shown below
Generic Forms and Brand names of Fluorouracil Cream (Generic Carac)
Flonida Cream manufactured by Shalaks, India is an effective treatment for for the topical treatment of multiple actinic (solar) keratoses. Carac Cream which has the active ingredient Fluorouracil is also sold as Fluorouracil Topical, Efudex, Fluoroplex and under various other brand names.
Flonida Cream - Preparations
Flonida Cream is available as 10 g tubes of 1% and 5% concentration.
Flonida Cream (Fluorouracil) - Uses
Fluorouracil in the form of Flonida Cream is used for the topical treatment of multiple actinic or solar keratoses of the face and anterior scalp. It is also used to treat other conditions such as basal cell carcinomas of the skin, Bowen's disease (a type of skin cancer), psoriasis, genital warts and porokeratosis (an unusual inherited skin condition causing dry patches on the arms and legs).
Flonida Cream - Storage Requirements
Flonida Cream is to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep out of the reach of children and pets.
Flonida Cream (Generic Carac) - Warninngs and Precautions
There exists the possibility for a delayed hypersensitivity reaction to Fluorouracil Cream. Hence patch testing for hypersensitivity may be inconclusive. The patient should avoid prolonged exposure to sunlight or any other forms of ultraviolet irradiation during treatment with Flonida Cream, as the intensity of the reaction may be increased.
Possibility exists of increased absorption through ulcerated or inflamed skin. Flonida Cream has to be applied with care near the eyes, nose, and mouth. Excessive reaction may occur in these areas due to irritation from accumulation of the medication. Flonida Cream is applied with the fingers, and the hands should be washed thouroughly soon afterwards. Patients should discontinue therapy with Fluorouracil Cream if symptoms of DPD enzyme deficiency develop. In rare cases, unexpected, systemic toxicity (e.g. stomatitis, diarrhea, neutropenia, and neurotoxicity) associated with parenteral administration of fluorouracil has been attributed to deficiency of DihydroPyrimidine Dehydrogenase "DPD" activity.
Flonida Cream (Fluorouracil) - Overdosage
Normally, overdosage of Flonida Cream will not cause acute problems. If Flonida Cream accidentally comes in contact with the eyes, flush the eyes with water or normal saline. If Flonida Cream is accidentally ingested, induce emesis and gastric lavage.
Flonida Cream (Generic Carac) - Dosage
Clean the affected area properly and wait 10 minutes before applying Flonida Cream (Generic Carac). Sufficient quantity of the medication has to be applied to cover the entire face or any other affected areas. Avoid contact with the eyes, eyelids, nostrils, and mouth. Apply the medication twice daily with fingertips and wash hands immediately afterwards. Normally a treatment period of two to six weeks is usually required. Increasing the frequency of application and a longer period of administration with Flonida Cream may be required on areas other than the head and neck.
Flonida Cream (Generic Carac) - Contraindications
Fluorouracil, the active ingredient in Flonida Cream may cause fetal harm when administered to a pregnant woman. Hence, Flonida Cream (Generic Carac) is contraindicated in women who are or may become pregnant. This medication should not be used by patients who are allergic to Fluorouracil or to any of the inactive components present in Flonida Cream.
Side Effects Of Flonida Cream (Fluorouracil Cream)
The most common side effects of are Pain, Pruritus, Burning, Irritation, Inflammation, allergic contact dermatitis and telangiectasia. Rarely, hyperpigmentation and scarring have also been reported.
