Generic Pamelor Capsules - Active Ingredient And Chemical structure
The active ingredient contained in Generic Pamelor Capsules (Sensival) is Nortriptyline Hydrochloride. The structure is shown below
Generic Forms and Brand names of Pamelor Capsules (Nortriptyline Hydrochloride)
The Generic forms of Pamelor (Nortriptyline Hydrochloride) are Primox manufactured by SUN Pharmaceuticals, India and Sensival manufactured by Wallace LifeStyle, India. Generic Pamelor Capsules which has the active ingredient Nortriptyline Hydrochloride is also sold under various other trade names such as Aventyl, Norpress, Allegron, Notrilen and Sensoval.
Generic Pamelor (Nortriptyline HCl) - Preparations
Nortriptyline HCl in the form of Primox and Sensival is available as tablets of 25 mg.
Generic Pamelor (Nortriptyline HCl) - Storage Requirements
Primox and Sensival tablets are to be stored at room temperature (15°C to 25°C). Store away from heat, moisture, and light.
Generic Pamelor (Nortriptyline Hydrochloride) - Uses
Generic Pamelor in the form of Sensival tablets and Primox tablets are used as an effective treatment for major depression. They are also used to treat childhood nocturnal enuresis (bedwetting). In addition, Generic Pamelor is also used sometimes for chronic illnesses such as chronic fatigue syndrome, chronic pain and migraines, and labile affect in some neurological conditions.
Generic Pamelor (Nortriptyline Hydrochloride) Dosage
The usual Adult Dose for generic Pamelor (Sensival and Primox) is 25 mg three or four times daily. The dosage should start at a low level and be increased if necessary. The maximum dose should not exceed 150 mg/day. In case of Elderly or Adolescent Patients, the dosage should be 30 to 50 mg/day, in divided doses, or the total daily dosage may optionally be given once a day.
Side Effects Of Generic Pamelor (Nortriptyline Hydrochloride)
Patients hypersensitive to Nortriptyline HCl should not be given Primox and Sensival.The side effects of Generic Pamelor are
Cardiovascular - Hypotension, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke.
Psychiatric - Confusional states (especially in the elderly) with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; insomnia, panic, nightmares; hypomania; exacerbation of psychosis.
Neurologic - Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors peripheral neuropathy; extrapyramidal symptoms; seizures, alteration in EEG patterns; tinnitus.
Anticholinergic - Dry mouth and, rarely, associated sublingual adenitis; blurred vision, disturbance of accommodation, mydriasis; constipation, paralytic ileus; urinary retention,
delayed micturition, dilation of the urinary tract.
Allergic - Skin rash, petechiae, urticaria, itching, photosensitization (avoid excessive exposure to sunlight); edema (general or of face and tongue), drug fever, crosssensitivity with other tricyclic drugs.
Hematologic - Bone marrow depression, including agranulocytosis; eosinophilia; purpura; thrombocytopenia.
Gastrointestinal - Nausea and vomiting, anorexia, epigastric distress, diarrhea, peculiar taste, stomatitis, abdominal cramps, blacktongue.
Endocrine - Gynecomastia in the male and breast enlargement and galactorrhea in the female. Increased or decreased libido, impotence; testicular swelling; elevation or depression of blood
sugar levels; syndrome of inappropriate ADH (antidiuretic hormone) secretion.
Other Side Effects - Jaundice (simulating obstructive), altered liver function; weight gain or loss; perspiration; flushing; urinary frequency, nocturia; drowsiness, dizziness, weakness, fatigue;headache; parotid swelling; alopecia.
Though the Withdrawal Symptoms do not indicate addiction, abrupt stopping of treatment after prolonged therapy may produce nausea, headache, and malaise.
