Tuesday, July 19, 2011

Atorlip Tablets | Generic Lipitor | Uses | Dosage | Side effects

Atorlip Tablets (Generic Lipitor) - Active Ingredient And Chemical structure

The active ingredient contained in Generic Lipitor Tablets is Atorvastatin Calcium . Atorvastatin calcium is a white to off-white crystalline powder that is is very slightly soluble in distilled water. The structure is shown below

Structure Of Atorvastatin Calcium


Atorlip Tablets (Generic Lipitor) - Uses


Generic Lipitor in the form of Atorlip Tablets is used for
1.Prevention of Cardiovascular Disease
In adult patients who do not have clinically evident coronary heart disease, but have multiple risk factors for coronary heart disease such as age, smoking, hypertension, low HDL-C, or a family history of early coronary heart disease, Atorlip Tablets are indicated to:
•Reduce the risk of myocardial infarction
•Reduce the risk of stroke
•Reduce the risk for revascularization procedures and angina
In patients with type 2 diabetes, and without clinically evident coronary heart disease , but have multiple risk factors for coronary heart disease such as retinopathy, albuminuria, smoking, or hypertension, Atorlip is indicated to:
•Reduce the risk of myocardial infarction
•Reduce the risk of stroke
In patients with clinically evident coronary heart disease, LIPITOR is indicated to:
•Reduce the risk of non-fatal myocardial infarction
•Reduce the risk of fatal and non-fatal stroke
•Reduce the risk for revascularization procedures
•Reduce the risk of hospitalization for CHF
•Reduce the risk of angina
2. Hyperlipidemia
Atorlip Tablets are indicated:
*As an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson Types IIa and IIb);
*As an adjunct to diet for the treatment of patients with elevated serum TG levels (Fredrickson Type IV);
*For the treatment of patients with primary dysbetalipoproteinemia (Fredrickson Type III) who do not respond adequately to diet;
*To reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable;
* As an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the following findings are present:
a.LDL-C remains = 190 mg/dL or
b.LDL-C remains = 160 mg/dL and:
•there is a positive family history of premature cardiovascular disease or
•two or more other CVD risk factors are present in the pediatric patient


Atorlip Tablets (Generic Lipitor) - Preparations

Atorlip is available as tablets of 5 mg, 10 mg, 20 mg and 40 mg. Each film coated tablet contains Atorvastatin calcium equivalent to Atorvastatin 5 mg, 10 mg, 20 mg and 40 mg respectively.



Generic Forms and Brand names of Lipitor (Atorvastatin Calcium)

Atorlip Tablets manufactured by Cipla Ltd., India is an effective treatment for prevention of Cardiovascular Disease in adult patients without clinically evident Coronary heart disease (CHD) , but with multiple risk factors for CHD. It is also used for the treatment of Hypercholesterolemia , and in n patients with type 2 diabetes and In patients with clinically evident CHD to reduce the risk of myocardial infarction. Generic Lipitor which has the active ingredient Atorvastatin Calcium is also sold as Atoris, Lipvas, Sortis, Torvast, Torvacard, Tortalip, Tulip and under various other brand names.



Atorlip Tablets (Generic Lipitor) - Storage Requirements

Atorlip Tablets are to be stored at room temperature (15°C to 30°C). Store away from heat, moisture, and light. Keep away from children and pets.


Atorlip Tablets (Generic Lipitor) - Contraindications

Atorlip Tablets are contraindicated in the following cases:
1.Patients having Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels
2.Women who are pregnant or may become pregnant
3.Nursing mothers
4.Hypersensitivity to any component of this medication


Atorlip Tablets (Generic Lipitor) - Dosage


The Adult Dose range for Generic Lipitor tablets 10 to 80 mg once daily. The recommended starting dose of Atorlip is 10 or 20 mg once daily for most adult patients. The recommended starting dose for Pediatric patients is 10 mg once daily with the maximum recommended dose at 20 mg once daily. Patients which require large LDL-C reduction (>45%) may start at 40 mg once daily.


Side Effects Of Atorlip Tablets (Generic Lipitor)

The most common side effects of Atorlip in patients are nasopharyngitis, arthralgia, diarrhea, pain in extremity, urinary tract infection, Dyspepsia, Nausea, Musculoskeletal pain, Muscle Spasms, Myalgia, Insomnia and Pharyngolaryngeal pain.


Further Information


Prescribing Information